Natural product separation method with improved separation efficiency

Abstract

The invention discloses a natural product separation method with improved separation efficiency. The method comprises steps as follows: a fresh natural product is frozen in the ultra-low temperature environment and soaked in liquid nitrogen; the natural product is crushed in the low-temperature environment; a hydrophobic organic matter, hydrophilic low-molecular organic matter and an inorganic salt solution are added to the crushed natural product in proportion; extraction and ultrasonic extraction are performed; 6) solid-liquid separation is performed. According to the natural product separation method, the fresh plant raw material is subjected to low-temperature freezing and crushing treatment, the crushing mode does not require material drying during conventional crushing, the crushed material is in a vitrification state, cell walls and organelle of cells are damaged simultaneously, the state of the crushed material is greatly different from that of materials obtained by use of an ordinary crushing device, active ingredients inside and outside the cells can be sufficiently released, decomposition and derivation of the active ingredients in the processing process of the natural product are reduced, and the extraction rate is increased.

Description

technical field [0001] The invention relates to a natural product separation method, in particular to a natural product separation method with improved separation efficiency. Background technique [0002] Active ingredients of natural products refer to substances that are biologically active and can be used as medicinal or nutritional health value, generally based on plants, and active ingredients include polysaccharides, proteins, alkaloids, flavonoids, anthraquinones and tea quinones, Terpenes and steroids, saponins, coumarins and lipids, lignans, cardiac glycosides, phenolic acids, glycosides, volatile oils, pigments, etc. [0003] The extraction method of active ingredients of natural products is mainly solvent extraction, and its separation principle is mainly based on the difference in the distribution characteristics of substances in two immiscible liquid phases. For active ingredients with a large difference in polarity, it is often necessary to select different sol...

AI Technical Summary

Problems solved by technology

[0004] The technical problem to be solved by the present invention is that the extraction rate of the active ingredient in the existing natural product separation method is low, it is easy to cause the decomposition of the active ingredient, and the efficiency is low, resulting in waste of the active ingredient. The purpose is to provide a natural product that improves the separation efficiency. The separation method uses low-temperature freezing and pulverization of fresh plant raw materials. This pulverization method does not require drying of the material during conventional pulverization, so that the pulverized material reaches a "vitrified" state, and the cell walls and organelles of the cells At the same time, the crushed material is very different from the state of the material obtained after using ordinary crushing equipment. It can fully release the active ingredients inside and outside the cells, reduce the decomposition and derivation of the active ingredients in the natural product process, and ensure that The active ingredients and relative content in the extract are basically the same as the original natural product, improving the extraction rate