Methyl propionate preparation method

Abstract

The invention relates to a methyl propionate preparation method, which comprises carrying out a reaction on raw materials including ethylene, carbon monoxide and methanol in a fixed bed reactor at a reaction temperature of 150-250 DEG C, wherein a reaction pipe is filled with a ruthenium-loaded metal oxide catalyst, and the reaction pipe with the catalyst is placed in the fixed bed reactor. According to the present invention, the reaction has the 100% atomic economy, does not produce by-products, and uses the noble metal-loaded metal oxide or the molecular sieve as the catalyst, wherein the catalyst is easily prepared and efficiently catalyzes the reaction, and the yield of methyl propionate can reach over 80% .

Description

technical field [0001] The invention relates to a method for preparing methyl propionate, in particular to the preparation of methyl propionate through the methoxy carbonylation reaction of methanol, carbon monoxide and ethylene. Background technique [0002] Methyl propionate has important uses in medicine, chemical industry, fuel, etc. It is mainly used as alkyl esters and derivatives of alkyl esters, and is also an important pharmaceutical intermediate and organic synthesis intermediate. Methyl propionate can be used to synthesize methyl methacrylate (MMA), and MMA is a monomer for synthesizing polymethyl methacrylate (p-MMA), which is widely used in glass, medical equipment and other fields. [0003] Methods for the preparation of methyl propionate have been reported. Ferreira, A.C et al. (Angew.Chem.Int Ed.2007, 46, 2273), Preparation of methyl propionate by catalyzed methoxycarbonylation of ethylene with boric acid ester as acid promoter in the presence of palladium a...

AI Technical Summary

Problems solved by technology

However, there are problems in the catalytic system used in the preparation of methyl propionate by the methoxycarbonylation reaction: for example: the homogeneous palladium catalyst has high energy consumption for separation, and the preparation of the ionic liquid catalyst is tedious and expensive. In addition, in the reported catalytic system Most of them need to add additional acid additives, etc., so the development of a high-efficiency and low-cost heterogeneous catalytic system to achieve high-efficiency preparation of methyl propionate has important application prospects

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