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Traditional Chinese medicine enzyme for treating osteocarcinoma and preparation method thereof

A technology of traditional Chinese medicine and enzymes, applied in the field of biological enzyme preparations, can solve the problems of low utilization rate of traditional Chinese medicine, unpleasant smell, drug toxicity, etc., and achieve the effects of helping rehabilitation, improving bone tissue function, and reducing irritation.

Inactive Publication Date: 2018-05-25
胡广
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most traditional Chinese medicines are in the form of decoctions or granules. Traditional medicines lead to low utilization of Chinese medicines, bitter taste, unpleasant smell, drug toxicity, and pesticide residues.

Method used

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  • Traditional Chinese medicine enzyme for treating osteocarcinoma and preparation method thereof
  • Traditional Chinese medicine enzyme for treating osteocarcinoma and preparation method thereof

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Experimental program
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Effect test

preparation example Construction

[0043] A preparation method of a described Chinese medicine enzyme for the treatment of bone cancer, comprising

[0044] Ultrasonic extraction step: drying the raw materials of traditional Chinese medicine according to the proportion, and then pulverizing them respectively to obtain traditional Chinese medicine powder, adding water to the traditional Chinese medicine powder and stirring evenly, and then ultrasonically extracting each kind of traditional Chinese medicine powder separately to obtain a traditional Chinese medicine extract;

[0045] Enzymatic hydrolysis step: mixing each of the above-obtained traditional Chinese medicine extracts and adding compound enzymes for enzymatic hydrolysis to obtain an enzymatic hydrolysis solution;

[0046] Sterilization step: sterilize the above enzymatic hydrolyzate in a sterilizer;

[0047] Strain activation and culture steps: dissolve yeast powder and acetic acid bacteria in liquid medium respectively, shake to dissolve the bacteria ...

Embodiment 1

[0063] A traditional Chinese medicine enzyme for treating bone cancer is an enzyme prepared by fermenting traditional Chinese medicine raw materials through compound bacteria;

[0064] The traditional Chinese medicine raw materials include: 10 parts by weight of Hedyotis diffusa, 15 parts by weight of Banzhilian, 15 parts by weight of Purple Salvia, 10 parts by weight of Rhizoma Drynariae; 5 parts by weight of rhubarb, 15 parts by weight of Coix seed, 10 parts by weight of Curcuma, 10 parts by weight of bone-seeking wind, 10 parts by weight of Sophora flavescens, 15 parts by weight of Tuckahoe, 10 parts by weight of Sophora japonica, 15 parts by weight of elderberry, 15 parts by weight of red peony root, 15 parts by weight of vine pear root, 15 parts by weight of Agrimony , 10 parts by weight of frankincense, 10 parts by weight of raw ground, 10 parts by weight of Sophora flavescens;

[0065] The compound bacteria include a concentration of 1.0 × 10 8 CFU / mL of yeast and a co...

Embodiment 2

[0074] A traditional Chinese medicine enzyme for treating bone cancer is an enzyme prepared by fermenting traditional Chinese medicine raw materials through compound bacteria;

[0075] The traditional Chinese medicine raw materials include: 20 parts by weight of Hedyotis diffusa, 25 parts by weight of Banzhilian, 25 parts by weight of Purple Salvia, 10 parts by weight of Rhizoma Drynariae; 5 parts by weight of rhubarb, 15 parts by weight of Coix seed, 10 parts by weight of Curcuma, 10 parts by weight of bone-seeking wind, 10 parts by weight of Sophora flavescens, 15 parts by weight of Tuckahoe, 10 parts by weight of Sophora japonica, 15 parts by weight of elderberry, 15 parts by weight of red peony root, 15 parts by weight of vine pear root, 15 parts by weight of Agrimony , 10 parts by weight of frankincense, 10 parts by weight of raw ground, 10 parts by weight of Sophora flavescens;

[0076] The compound bacteria include a concentration of 1.8 × 10 8 CFU / mL of yeast and a co...

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Abstract

The invention discloses a traditional Chinese medicine enzyme for treating osteocarcinoma. The enzyme is prepared by subjecting traditional Chinese medicine raw materials to fermentation through compound bacteria, the traditional Chinese medicine raw materials include hedyotis diffusa, scutellaria barbata, savia miltiorrhiza, rhizoma drynariae, rheum officinale, semen coicis, curcuma zedoary, herba aristolochiae mollissimae, radix sophorae flavescentis, rhizoma smilacis glabrae, fructus sophorae, elderberry, radix paeoniae rubra, radix actinidiae chinenssis, herba agri, frankincense, radix rehmanniae and, and the compound bacteria include yeast and acetic bacteria. The invention further provides a preparation method of the traditional Chinese medicine enzyme. By introducing multi-bacteriumcoexistence technology, the traditional Chinese medicine enzyme is prepared after various Chinese medicinal herbs are fermented, the administration mode of traditional Chinese medicine for treating rectum is improved, a micromolecular traditional Chinese medicine enzyme is obtained, irritation of traditional Chinese medicine to intestines and stomach is lowered, and absorptivity of beneficial ingredients in the traditional Chinese medicine is improved.

Description

technical field [0001] The invention belongs to the technical field of biological enzyme preparations, in particular to a traditional Chinese medicine enzyme for treating bone cancer and a preparation method thereof. Background technique [0002] Cancer pain seriously affects the quality of life of cancer patients and is one of the most common symptoms of cancer patients. The World Health Organization has made aggressive treatment of cancer pain one of four priorities in the Comprehensive Cancer Programme. Cancer pain is one of the most common symptoms in patients with advanced clinical malignant tumors, and 75% to 95% of patients with advanced cancer and metastatic cancer have cancer pain. Bone is the most common metastatic site of advanced malignant tumors. Bone cancer pain is a serious cancer pain, which mainly originates from primary bone tumor or secondary bone metastases such as lung cancer, breast cancer, and prostate cancer. At present, there are about 3 million ne...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/19A61P35/00
CPCA61K9/19A61K36/126A61K36/185A61K36/264A61K36/324A61K36/35A61K36/489A61K36/53A61K36/537A61K36/539A61K36/65A61K36/708A61K36/71A61K36/73A61K36/748A61K36/804A61K36/8888A61K36/896A61K36/8994A61K36/90A61K36/9066A61K2236/19A61K2236/331A61K2236/51A61K2300/00
Inventor 胡广李秋菊胡均霖
Owner 胡广