Traditional Chinese medicinal composition for treating angina pectoris of coronary heart disease and preparation method thereof

A technology of coronary heart disease angina pectoris and composition, which is applied in the field of traditional Chinese medicine composition for treating coronary heart disease angina pectoris and its preparation, which can solve the problems of treating the symptoms but not the root cause, nephrotoxicity, and poor curative effect of drugs, and achieve reasonable compatibility and remarkable therapeutic effect Effect

Inactive Publication Date: 2018-07-20
NANYANG INST OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Although there are many anti-angina pectoris drugs in Western medicine, if taken for a long time, patients will develop tolerance, which will make the efficacy of the d

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] In this embodiment, a traditional Chinese medicine composition for treating angina pectoris of coronary heart disease comprises the following raw materials in parts by weight: 15 g of Puhuang, 15 g of Eupatorium, 10 g of Hawthorn, 20 g of Corydalis Corydalis, 15 g of Millet Spatholobus, 10 g of Peach Kernel, 10 g of Safflower, Leech 15g, earthworm 15g, blood jellyfish 5g, salvia miltiorrhiza 20g, trichosanthes 20g, achyranthes bidentata 10g.

[0047] The preparation method of the above-mentioned traditional Chinese medicine composition comprises the following steps: weighing each raw material according to the above weight, mixing each raw material medicine, adding ethanol equivalent to 5 times the total weight of each raw material medicine, soaking for 1.0 h, and then heating and extracting at 80°C 3 times, 1 hour each time, combine the extracts; take the supernatant after standing still, then filter through 140 mesh, and then ultrafilter through an ultrafiltration colum...

Embodiment 2

[0049] In this embodiment, a traditional Chinese medicine composition for treating angina pectoris of coronary heart disease comprises the following raw materials in parts by weight: 20 g of Puhuang, 18 g of Eupatorium, 15 g of Hawthorn, 20 g of Corydalis Corydalis, 20 g of Millet Spatholobus, 15 g of Peach Kernel, 15 g of Safflower, Leech 15g, earthworm 15g, blood dried fruit 8g, salvia miltiorrhiza 20g, trichosanthes 25g, achyranthes bidentata 15g.

[0050] The preparation method of the above-mentioned traditional Chinese medicine composition comprises the following steps: weighing each raw material according to the above weight, mixing each raw material drug, adding ethanol equivalent to 6 times the total weight of each raw material drug, soaking for 1.5 hours, and then heating and extracting at 80°C 2 times, 1.5 hours each time, combine the extracts; take the supernatant after standing still, then filter through 120 mesh, and then ultrafilter through an ultrafiltration colu...

Embodiment 3

[0052] In this embodiment, a traditional Chinese medicine composition for treating angina pectoris of coronary heart disease comprises the following raw materials in parts by weight: 25g of Puhuang, 25g of Eupatorium, 18g of Hawthorn, 25g of Corydalis Corydalis, 30g of Millet Spatholobus, 20g of Peach Kernel, 20g of Safflower, Leeches 20g, Earthworm 25g, Dracaena 10g, Salvia miltiorrhiza 25g, Trichosanthes 30g, and Achyranthes bidentata 20g.

[0053] The preparation method of the above-mentioned traditional Chinese medicine composition comprises the following steps: weighing each raw material according to the above weight, mixing each raw material medicine, adding ethanol equivalent to 6 times the total weight of each raw material medicine, soaking for 1.0 h, and then heating and extracting at 80°C 3 times, 1.0 h each time, combine the extracts; take the supernatant after standing still, then filter through 140 mesh, and then ultrafilter through an ultrafiltration column with a...

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Abstract

The invention discloses a traditional Chinese medicinal composition for treating the angina pectoris of coronary heart disease and a preparation method thereof. The traditional Chinese medicinal composition is prepared from the following bulk drugs in parts by weight: 15 to 30 parts of pollen typhae, 15 to 35 parts of herba lycopi, 10 to 30 parts of fructus crataegi, 20 to 30 parts of rhizoma corydalis, 15 to 45 parts of caulis spatholobi, 10 to 30 parts of semen persicae, 10 to 30 parts of flos carthami, 15 to 25 parts of hirudo, 15 to 30 parts of pheretima, 5 to 20 parts of sangusis draconis, 20 to 45 parts of radix salviae miltiorrhizae, 20 to 35 parts of fructus trichosanthis and 10 to 35 parts of radix cyathulae. The traditional Chinese medicinal composition provided by the inventionhas the functions of activating blood circulation, relieving pain, eliminating phlegm, removing blood stasis, clearing and activating channels and collaterals, invigorating the kidney and nourishing the heart, and is applicable to treating patients suffered from a coronary heart disease with the symptoms of blood stasis, phlegm obstruction and heart and kidney deficiencies at the same time and theangina pectoris.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating coronary heart disease angina pectoris and a preparation method thereof. Background technique [0002] Coronary atherosclerotic heart disease, referred to as coronary heart disease, also known as ischemic heart disease, includes myocardial ischemic diseases caused by coronary atherosclerosis that narrows or blocks it, or its functional changes and spasms. According to modern medicine, angina pectoris of coronary heart disease is a clinical syndrome mainly manifested by episodic chest pain or chest discomfort caused by coronary atherosclerosis leading to lumen stenosis or coronary artery spasm, myocardial transient ischemia and hypoxia. The disease mostly occurs in people over the age of 40, more men than women, and most of them are mental workers. In recent years, the incidence of coronary heart diseas...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61K36/889A61P9/10A61K35/62
CPCA61K35/62A61K36/21A61K36/286A61K36/428A61K36/486A61K36/53A61K36/537A61K36/66A61K36/734A61K36/736A61K36/88A61K36/889A61K36/896A61K2236/33A61K2236/331A61K2236/39A61K2236/51A61K2236/55A61K2300/00
Inventor 杨雷刘暖毛秉豫张培华张千一李星赵威
Owner NANYANG INST OF TECH
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