Medical catheter with copper-containing coating and method for producing the same
A technology of medical catheter, copper coating
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0040] Preparation of coatings with gradient copper-loaded particles on medical catheters by layer-by-layer chemical grafting:
[0041] Copper-loaded microspheres with active functional groups such as hydroxyl and carboxyl groups were immobilized on natural degradable chitosan polymers with amino and hydroxyl groups by layer-by-layer chemical grafting, and the amount of copper loaded in each layer was gradient. Copper ions are released through layer gradient, and the biofunctionalization of copper-containing coatings can be adjusted.
[0042] (1) Preparation of copper-loaded microspheres
[0043] ① Weigh 0.05g, 0.2g and 0.5g CuCl 2 , and were dissolved in 5mL distilled water to prepare three homogeneous solutions;
[0044] ② Dissolve 1.0 g of PACA in a mixed solution of chloroform and acetone (wherein the volume ratio of chloroform: acetone is 3:2), and prepare a PACA organic solution with a mass volume concentration of 100 mg / mL;
[0045] ③Weigh 1.0g of PVA, dissolve it in d...
Embodiment 2
[0061] Preparation of coatings with gradient copper-loaded microspheres on medical catheters by layer-by-layer electrostatic adsorption method:
[0062] (1) Prepare an aqueous solution of negatively charged sodium hyaluronate (concentration 1-5%), and prepare a hyaluronic acid coating on the inner / outer surface of the medical catheter by leaching;
[0063] (2) Preparation of copper-loaded microspheres
[0064] ①Weigh 0.20g of chitosan into a 250mL single-necked round bottom flask, add 250mL of 2% (mass fraction) acetic acid solution, turn on the electric stirring device and stir slowly until the chitosan is completely dissolved.
[0065] ② Add Span-80 0.4mL and Tween-80 0.6mL while stirring, and continue stirring for 30min to form a uniform, transparent and stable microemulsion. Then add 0.05g copper sulfate powder, stir at high speed to make it spread evenly;
[0066] ③ Then, slowly drop 1mol·L -1 NaOH solution, while stirring at a constant speed, use the PHS-3B precision ...
PUM
Property | Measurement | Unit |
---|---|---|
diameter | aaaaa | aaaaa |
size | aaaaa | aaaaa |
thickness | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com