A kind of traditional Chinese medicine composition, gel and its preparation method and application

Abstract

The invention discloses a traditional Chinese medicine composition gel for treating eczema and a preparation method thereof. The traditional Chinese medicine composition gel is extracted from three kinds of traditional Chinese medicines, comfrey root, mountain bean root and coptis chinensis, respectively, and then mixed with Carbomer 940 and sodium carboxymethyl cellulose in a certain proportion after vacuum concentration and freeze-drying. , ethanol, cosolvent, preservative, penetration enhancer, acid-base regulator, and deionized water to form a traditional Chinese medicine composition gel. According to the theory of traditional Chinese medicine, the freeze-dried powder of the three kinds of extracts is mixed with Litsea cubeba essential oil, blue eucalyptus leaf oil and natural borneol according to the prescription ratio to form a traditional Chinese medicine extract. Guided by the theory of traditional Chinese medicine, the invention selects pure natural traditional Chinese medicine raw materials as raw materials, has few medicinal flavors, scientific compatibility, little toxic and side effects, and no drug resistance. Through clinical verification, the gel prepared by the invention has the characteristics of definite curative effect, difficult recurrence, controllable quality and low cost.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparation, in particular to a traditional Chinese medicine composition, a gel and a preparation method and application thereof. Background technique [0002] Eczema is a skin inflammatory reaction with pleomorphic skin lesions and exudative tendency, and is a commonly encountered and frequently-occurring disease. Can happen all year round. Clinically, the affected area is characterized by severe itching, exudate, hypertrophy, lichenification, easy chronicity, and recurrent attacks, which seriously affect the daily life and study work of patients. Especially for patients whose diseased part is on the face, their physical and mental health have been seriously affected. Therefore, the prevention and treatment of this disease is an important medical and social problem. [0003] At present, the common traditional Chinese medicine ointment formulations on the market are relativ...

AI Technical Summary

Problems solved by technology

[0003] At present, the common traditional Chinese medicine ointment formulations on the market are relatively greasy in texture, poor in air permeability, unable to control the sustained release of the drug, and the drug effect is not long-lasting, which is not conducive to clinical use, and will contaminate clothing and other technical defects

However, the water-extracted or alcohol-extracted external extracts of traditional Chinese medicine involved in other technical materials will volatilize too quickly, resulting in drug shedding and poor absorption.

Or in some technical materials, the published extraction method does not consider the selected extraction solvent and extraction temperature, resulting in low extraction efficiency of active ingredients

There are some existing formulas, not only the number of medicinal flavors is complex, but also most of the original medicinal materials are simply crushed into fine powder and mixed to prepare. The unit of effective drug in contact with the affected area is less, and the texture of the granular drug is not uniform and fine, which is not conducive to drug absorption.

Although there are many types of traditional Chinese medicine compound preparations and western medicines currently used to treat eczema, the clinical curative effect is not satisfactory to patients, and recurrent attacks cause physical and mental harm to patients.

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