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Ginseng glycopeptide injection medicine composition as well as preparation method and application thereof

A technology for injection and composition, applied in the field of ginseng glycopeptide injection pharmaceutical composition and preparation thereof, can solve the problems of slow application research of ginseng polysaccharide and ginseng polypeptide drug and the like

Inactive Publication Date: 2018-09-21
JILIN BAINIAN HANKE PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Many studies have shown that ginseng also has a hypoglycemic effect. The ginseng polysaccharides and ginseng polypeptides contained in it are the active ingredients for hypoglycemia, which play an important role in the regulation of blood sugar in the human body. However, the research on the drug application of ginseng polysaccharides and ginseng polypeptides is still relatively slow.

Method used

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  • Ginseng glycopeptide injection medicine composition as well as preparation method and application thereof
  • Ginseng glycopeptide injection medicine composition as well as preparation method and application thereof
  • Ginseng glycopeptide injection medicine composition as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A ginseng glycopeptide injection pharmaceutical composition, comprising the following raw materials in parts by weight: 120 parts of ginseng glycopeptide, 150 parts of soybean oil for injection, 20 parts of lecithin for injection, 30 parts of glycerin for injection, and 3 parts of sodium chloride , 20 parts of Tween 80 and 800 parts of water for injection.

[0024] A preparation method of the above-mentioned ginseng glycopeptide injection pharmaceutical composition, comprising the following steps:

[0025] S1. Weigh the prescribed amount of ginseng glycopeptide, add an appropriate amount of water for injection to dissolve it, add 0.01% (W / V) activated carbon and stir for 25 minutes, filter and decarbonize and cool to room temperature;

[0026] S2. Dissolving glycerin for injection, sodium chloride, and Tween 80 in water for injection to obtain an aqueous phase;

[0027] S3. dissolving lecithin for injection in soybean oil for injection to obtain an oil phase;

[0028]...

Embodiment 2

[0032] A ginseng glycopeptide injection pharmaceutical composition, comprising the following raw materials in parts by weight: 180 parts of ginseng glycopeptide, 170 parts of soybean oil for injection, 35 parts of lecithin for injection, 35 parts of glycerin for injection, and 5 parts of sodium chloride , 18 parts of Tween 80 and 950 parts of water for injection.

[0033] A preparation method of the above-mentioned ginseng glycopeptide injection pharmaceutical composition, comprising the following steps:

[0034] S1. Weigh the prescribed amount of ginseng glycopeptide, add an appropriate amount of water for injection to dissolve it, add 0.03% (W / V) activated carbon and stir for 35 minutes, filter and decarbonize and cool to room temperature;

[0035] S2. Dissolving glycerin for injection, sodium chloride, and Tween 80 in water for injection to obtain an aqueous phase;

[0036] S3. dissolving lecithin for injection in soybean oil for injection to obtain an oil phase;

[0037]...

Embodiment 3

[0041] A ginseng glycopeptide injection pharmaceutical composition, comprising the following raw materials in parts by weight: 250 parts of ginseng glycopeptide, 200 parts of soybean oil for injection, 45 parts of lecithin for injection, 50 parts of glycerin for injection, and 8 parts of sodium chloride , 25 parts of Tween 80 and 1100 parts of water for injection.

[0042] A preparation method of the above-mentioned ginseng glycopeptide injection pharmaceutical composition, comprising the following steps:

[0043] S1. Weigh the prescribed amount of ginseng glycopeptide, add an appropriate amount of water for injection to dissolve it, add 0.04% (W / V) activated carbon and stir for 50 minutes, filter and decarbonize and cool to room temperature;

[0044] S2. Dissolving glycerin for injection, sodium chloride, and Tween 80 in water for injection to obtain an aqueous phase;

[0045] S3. dissolving lecithin for injection in soybean oil for injection to obtain an oil phase;

[0046...

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Abstract

The invention concretely discloses a ginseng glycopeptide injection medicine composition as well as a preparation method and application thereof. The injection medicine composition is prepared from the following raw materials in parts by weight: 100 to 300 parts of ginseng glycopeptide, 100 to 250 parts of soybean oil for injection, 10 to 50 parts of lecithin for injection, 20 to 60 parts of glycerin for injection, 2 to 10 parts of sodium chloride, 10 to 30 parts of Tween 80 and 700 to 1200 parts of water for injection. Experiments show that hepatic glycogen of each mouse in a ginseng glycopeptide injection group is more similar to a glycogen original numerical value of the mouse of a blank control group; the result also shows that an important effect is also achieved for regulating the hepatic glycogen of the mouses through continuous ginseng glycopeptide injection; an obvious inhibition effect can also be achieved on the increase of the mouse hepatic glycogen.

Description

technical field [0001] The invention relates to the technical field of ginseng extracts, in particular to a pharmaceutical composition of ginseng glycopeptide injection and its preparation method and application. Background technique [0002] Ginseng has been known as the "king of all herbs" since ancient times. It contains a variety of saponins and polysaccharides. Ginseng belongs to Araliaceae, a common medicinal material in Asia, and American ginseng is also widely used in North and Central America. It is mainly used for recovery after recovery, strengthening physical strength, regulating hormones, lowering blood sugar and controlling blood pressure, and controlling liver index and liver function. Ginseng contains a chemical substance called ginsenoside, which has obvious effects on regulating the central nervous system, strengthening the heart, anti-fatigue, regulating substance metabolism, etc., so it is effective in treating the nervous system, cardiovascular system, e...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K47/44A61K38/14A61P3/10
CPCA61K9/0019A61K9/08A61K38/14A61K47/44A61P3/10
Inventor 费青张丹张恒张戈
Owner JILIN BAINIAN HANKE PHARM CO LTD