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Preparation method of radix tetrastigme wall breaking orally-taken decoction piece

A technology of Sanyeqing and decoction pieces, which is applied in the field of preparation of Sanyeqing broken oral decoction pieces, can solve the problems of loss of essential substances, insufficient wall breaking rate, shortening drying time, etc.

Inactive Publication Date: 2018-10-19
CHANGSHA XIAORU INFORMATION TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The traditional processing method of clover decoction pieces: usually slices are baked and dried, then sulfur fumigated and put into woven bags. During the baking process, the essence is lost or destroyed, which significantly reduces the efficacy and active ingredients, and cannot be ignored. The most important thing is that the sulfur fumigation method in the traditional processing of clover pieces makes the mildewed clover become white and unrecognizable, and the residual sulfur dioxide is harmful to the human body, so that the safety and quality cannot be guaranteed, let alone the efficacy and quality of the medicine. curative effect
The invention shortens the drying time, reduces energy consumption, is convenient to store, has a long shelf life and stable quality, and can preserve the medicinal components of the original drug and restore the performance of the crude drug to the greatest extent, but has the problems of insufficient wall breaking rate and cumbersome preparation method

Method used

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  • Preparation method of radix tetrastigme wall breaking orally-taken decoction piece
  • Preparation method of radix tetrastigme wall breaking orally-taken decoction piece

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preparation example Construction

[0021] In an embodiment, a method for preparing oral decoction pieces of broken-walled Clover, comprises the following steps: (1) crushing and sieving: crushing the dry raw material, passing through a sieve of 80-120 mesh after crushing, to obtain coarse raw material powder; (2) Add baking soda powder to raw material coarse powder, add distilled water, react 0.5-1 hour at 60-70 ℃ of temperature; (3) add cellulase and α-amylase in the slurry of step 2, in Fermentation at 20-25°C; (4) The fermentation liquid was ultrasonically broken for 20-40 minutes, concentrated to 1 / 2-1 / 4 of the original volume, added with auxiliary materials, stirred evenly, and microwave sterilized; (5) After sterilization, The obtained material is granulated.

[0022] In step 2, the addition ratio of raw material coarse powder, baking soda powder, and distilled water is 5-10:0.05-0.1:20-50.

[0023] The addition ratio of baking soda powder, cellulase and α-amylase in step 3 is 5-10:5-8:2-5.

[0024] The...

Embodiment 1

[0029] A preparation method for oral decoction pieces of broken-walled Clover, comprising the following steps: (1) crushing and sieving: crushing dry raw materials, and passing through a 100-mesh sieve after crushing to obtain coarse raw material powder; Add baking soda powder, add distilled water, and react at a temperature of 65°C for 0.5 hours; (3) add cellulase and α-amylase to the slurry in step 2, and ferment at 25°C; (4) ferment the fermentation broth Ultrasound to break the wall for 30 minutes, concentrate to 1 / 3 of the original volume, add auxiliary materials, stir evenly, and carry out microwave sterilization; (5) After sterilization, granulate the obtained materials, and that is ready.

[0030] In step 2, the addition ratio of raw material coarse powder, baking soda powder, and distilled water is 8:0.08:32.

[0031] The addition ratio of cellulase and α-amylase in step 3 is 8:6:3.

[0032] Fermentation time 36 hours in the step 2.

[0033] In step 4, the ultrasoni...

Embodiment 2

[0037] A preparation method for oral decoction pieces of broken-walled Clover, comprising the following steps: (1) pulverizing and sieving: pulverizing the dry raw material, passing through an 80-mesh sieve after pulverizing, to obtain raw raw powder; Add baking soda powder, add distilled water, and react at a temperature of 70°C for 0.5 hours; (3) add cellulase and α-amylase to the slurry in step 2, and ferment at 25°C; (4) ferment the fermentation broth Ultrasound to break the wall for 20 minutes, concentrate to 1 / 4 of the original volume, add auxiliary materials, stir evenly, and carry out microwave sterilization; (5) After sterilization, granulate the obtained materials, and that’s it.

[0038] In step 2, the addition ratio of raw material coarse powder, baking soda powder, and distilled water is 5:0.1:20.

[0039] The addition ratio of cellulase and α-amylase in step 3 is 5:8:2.

[0040] Fermentation time 72 hours in the step 2.

[0041] In step 4, the ultrasonic power of...

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Abstract

The invention discloses a preparation method of a radix tetrastigme wall breaking orally-taken decoction piece, and belongs to the technical field of traditional Chinese medicine. The preparation method of the radix tetrastigme wall breaking orally-taken decoction piece comprises the following steps that (1) crushing and sieving are performed; dry raw materials are crushed; after the crushing, thecrushed raw materials pass through a screen net being 80 to 120 meshes; raw material coarse powder is obtained; (2) sodium bicarbonate powder is added into the raw material coarse powder; distilled water is added; reaction is performed for 0.5 to 1h at the temperature of 60 to 70 DEG C; (3) cellulase and alpha-amylase are added into slurry in the step 2; fermentation is performed at 20 to 25 DEGC; (4) fermentation liquid is subjected to ultrasonic wall breaking for 20 to 40min; concentration is performed to reach 1 / 2 to 1 / 4 of the original volume; auxiliary materials are added to be uniformly stirred; microwave sterilization is performed; (5) after the sterilization, the obtained materials are pelleted. The sodium bicarbonate powder, the cellulase and the alpha-amylase are used as a reinforcing system, so that the wall breaking rate of the radix tetrastigme wall breaking orally-taken decoction piece is improved.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a preparation method of broken-walled oral decoction pieces of Clover. Background technique [0002] Under the guidance of the theory of traditional Chinese medicine, Chinese herbal medicines and decoction pieces have gone through the changes of the times, and great reforms have taken place. In order to meet the needs of the modernization of traditional Chinese medicine, a new type of decoction piece - Chinese medicine broken wall decoction piece came into being. It is a new type of decoction piece of Chinese medicine developed on the basis of modern ultrafine pulverization technology. The medication form of modern Chinese medicine is a new and efficient modern decoction piece. [0003] Clover is a rare plant, so far it cannot be successfully cultivated artificially, and wild resources are decreasing day by day. The traditional proc...

Claims

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Application Information

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IPC IPC(8): A61K36/87A61K36/48A61K9/00
CPCA61K9/0095A61K36/48A61K36/87A61K2236/15A61K2236/19A61K2236/51
Inventor 不公告发明人
Owner CHANGSHA XIAORU INFORMATION TECH CO LTD
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