Preparation method of composition for improving sleep quality

A technology for improving sleep quality and composition, which is applied in drug combinations, medical preparations containing active ingredients, and pharmaceutical formulas, etc. It can solve the problems of insignificant sleep quality effects, difficulty in achieving drug effects, slow effects, etc., and achieve non-toxic Side effects, improvement of drug efficacy, and the effect of preventing recurrence

Inactive Publication Date: 2018-11-02
王兰亭
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Traditional Chinese medicine preparations for improving sleep quality have lower side effects than western medicines, but they are generally aimed at sleep disorders caused by yin deficiency, blood deficiency or heart fire. The effect is slow, and the effect of improving sleep quality is not obvious. make some people reluctant to take
There are also some health products that improve sleep quality, but it is difficult to achieve the effect of drugs, and the price is relatively high

Method used

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  • Preparation method of composition for improving sleep quality
  • Preparation method of composition for improving sleep quality
  • Preparation method of composition for improving sleep quality

Examples

Experimental program
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Effect test

preparation example Construction

[0023] A preparation method for improving sleep quality composition, the steps are as follows:

[0024] ①Take raw materials such as extracts of fenxin wood, acanthopanax and jujube for later use;

[0025] ②Crush the distracted wood to 100-200 mesh, then add water and soak for 30-45 minutes to obtain the distracted wood slurry;

[0026] ③ Add cellulase to the distracted wood pulp, stir evenly and ferment at 30-40°C for 3-5 days, then add sugar to it, and ferment Bacillus subtilis and Candida utilis at 35-50°C 1 to 2 days to obtain the fermentation stock solution;

[0027] ④ adding distilled water to the fermented stock solution, filtering, and freeze-drying the filtrate to obtain fermented heartwood;

[0028] Among them, the mass ratio of centipede, water, cellulase, sugar, Bacillus subtilis, Candida utilis and distilled water is 1:0.5~1:0.03~0.06:0.01~0.05:0.04~0.08:0.03~0.06 : 3 ~ 6; the activity of cellulase is 200 ~ 500U / g, the live bacteria content of Bacillus subtilis ...

Embodiment 1

[0041] A preparation method for improving sleep quality composition, the steps are as follows:

[0042] ①Take raw materials such as extracts of fenxin wood, acanthopanax and jujube for later use;

[0043] ②Crush the distracting wood to 100-200 mesh, then add water and soak for 30 minutes to obtain the distracting wood slurry;

[0044] ③ Add cellulase to the distracted wood pulp, stir evenly and ferment at 30°C for 3 days, then add sugar, Bacillus subtilis and Candida utilis to ferment at 35°C for 1 day to obtain a fermentation stock solution ;

[0045] ④ adding distilled water to the fermented stock solution, filtering, and freeze-drying the filtrate to obtain fermented heartwood;

[0046] Among them, the mass ratio of wood, water, cellulase, sugar, Bacillus subtilis, Candida utilis and distilled water is 1:0.5:0.03:0.01:0.04:0.03:3; the activity of cellulase is 200U / g, the live bacteria content of Bacillus subtilis and Candida utilis is 800 million / gram;

[0047] ⑤Add wa...

Embodiment 2

[0052] A preparation method for improving sleep quality composition, the steps are as follows:

[0053] ①Take raw materials such as extracts of fenxin wood, acanthopanax and jujube for later use;

[0054] ②Crush the distracted wood to 100-200 mesh, then add water and soak for 45 minutes to obtain the distracted wood slurry;

[0055] ③ Add cellulase to the distracted wood pulp, stir evenly and ferment at 40°C for 5 days, then add sugar, Bacillus subtilis and Candida utilis to ferment at 50°C for 2 days to obtain a fermentation stock solution ;

[0056] ④ adding distilled water to the fermented stock solution, filtering, and freeze-drying the filtrate to obtain fermented heartwood;

[0057] Among them, the mass ratio of wood, water, cellulase, sugar, Bacillus subtilis, Candida utilis and distilled water is 1:1:0.06:0.05:0.08:0.06:6; the activity of cellulase is 500U / g, the live bacteria content of Bacillus subtilis and Candida utilis is 1.2 billion / gram;

[0058] ⑤Add water...

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Abstract

The invention discloses a preparation method of a composition for improving sleep quality. A raw material diaphragma juglandis used in the composition prepared by the method is used for tonifying spleen and reinforcing kidney, and inducing astringency and enhancing vital essence, acanthopanax root is used for strengthening the middle warmer and boosting essence, tonifying primordial qi, promotingthe secretion of saliva, and soothing the nerves, and a jujube extract is used for tonifying spleen and harmonizing stomach, enhancing qi while engendering saliva, and detoxifying drug poisons. Each raw material composition prepared by the method has a good synergistic and enhanced effect, and has the effects of strengthening the middle warmer and boosting essence, tonifying spleen and reinforcingkidney, soothing the nerves, and tonifying spleen and harmonizing stomach, and achieves a good effect on improving sleep. The composition prepared by the method has a slightly sweet taste and high safety, can achieve a good purpose of improving sleep, has no toxic and side effects, does not cause dependence, can be taken for a long time, and can achieve the same improvement effect on sleep as western medicine. Relapse is not easy to occur after the composition is stopped from being taken.

Description

technical field [0001] The invention relates to the technical field of biological fermentation, and relates to a preparation method of a composition for improving sleep quality. Background technique [0002] People often have sleep disorders due to various events in their work and life. Except for pathological sleep disorders, most people with sleep disorders can achieve better sleep effects by taking sleeping pills orally. However, long-term oral sleeping pills are likely to cause dependence on the human body, and then affect health. People who take western medicine orally to improve sleep usually develop drug resistance, and then gradually increase the dose. Long-term oral administration of large amounts of western medicine is likely to cause certain damage to liver and kidney functions. Traditional Chinese medicine preparations for improving sleep quality have lower side effects than western medicines, but they are generally aimed at sleep disorders caused by yin deficie...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/725A61P25/20
CPCA61K36/52A61K36/254A61K36/725A61K2236/19A61K2236/331A61K2236/51A61P25/20A61K2300/00
Inventor 王兰亭
Owner 王兰亭
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