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A degradable bone rod implantation device and its preparation method

A technology for bone rods and devices, applied in the field of degradable bone rod implantation devices and its preparation, can solve problems such as the degradation of implant materials, implant failure, metal ion diffusion, etc., and achieve good regenerative function and repair Effects of bone damage

Active Publication Date: 2021-05-11
DONGGUAN EONTEC CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The main problem in the application of medical metal materials is the diffusion of metal ions to the surrounding tissues due to the corrosion of the physiological environment and the degradation of the properties of the implant material itself. The former may cause toxic side effects, and the latter often leads to implant failure.

Method used

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  • A degradable bone rod implantation device and its preparation method
  • A degradable bone rod implantation device and its preparation method
  • A degradable bone rod implantation device and its preparation method

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preparation example Construction

[0034] The present application also provides a preparation method of the degradable bone rod implantation device, comprising the following steps:

[0035] In-situ growth of Ca-P-Ag coating on the surface of degradable medical bone rod by micro-arc oxidation process;

[0036] The degradable medical bone-setting rod is a pure magnesium material or a magnesium alloy material, and the magnesium alloy material includes: Fe greater than 0 and less than or equal to 0.5wt%, Zn greater than 0 and less than or equal to 1wt%, greater than 0 and less than or equal to 0.6wt% of Mn, greater than 0 and less than or equal to 0.05wt% of Cu, 0.8wt% of Sr and the balance of Mg;

[0037] The coating is a Ca-P-Ag coating.

[0038] In the process of preparing the degradable bone rod implantation device, the present application prepared a Ca-P-Ag coating on the surface of the medical bone rod through a micro-arc oxidation process; the medical bone rod was prepared according to a method well known to ...

Embodiment 1

[0042] provide as figure 2 The medical bone-synthesizing rod shown, the diameter D of the bone-synthesized rod connected by the coaxial is 8mm, the height h 0 A base of 10mm with a diameter d of 4mm and a height h 1 The length W of the groove in the center of the bottom of the base is 6mm, and the height h 2 3mm; meanwhile, the bone bonding rod is a magnesium alloy material, which consists of 0.1wt% Fe, 0.6wt% Zn, 0.6wt% Mn, 0.02wt% Cu, 0.8wt% Sr and the rest of Mg;

[0043] The micro-arc oxidation process is used to in-situ grow Ca-P-Ag coating on the surface of the medical bone rod to obtain a degradable magnesium alloy bone rod implant device; the specific composition of the electrolyte in the micro-arc oxidation process is sodium silicate 40wt%+nano Hydroxyapatite powder 50wt% + sodium fluoride 5wt% + glycerin 2wt% + sodium hydroxide 2wt% + 1wt% nano-Ag powder + deionized water 2000mL, the specific process parameters are constant voltage 300V; pulse frequency 350Hz; Ra...

Embodiment 2

[0047] provide as figure 2 As shown in the medical bone rod, the bone rod is coaxially connected with a diameter D of 6 mm and a height h 0 A base of 8mm with a diameter d of 3mm and a height h 1 The length W of the groove in the center of the bottom of the base is 4mm, and the height h 2 2mm; meanwhile, the bone bonding rod is a magnesium alloy material, which consists of 0.4wt% Fe, 0.8wt% Zn, 0.4wt% Mn, 0.03wt% Cu, 0.8wt% Sr and the rest of Mg;

[0048] The Ca-P-Ag coating is grown in situ on the surface of the medical bone rod by using the micro-arc oxidation process to obtain a degradable magnesium alloy bone rod implant device; the specific composition of the electrolyte in the micro-arc oxidation process is sodium silicate 50wt%+nano HA powder 40wt% + sodium fluoride 5wt% + glycerin 2wt% + sodium hydroxide 2wt% + 1wt% nano-Ag powder + deionized water 2000mL, the specific process parameters are constant voltage 400V; pulse frequency 250Hz; duty cycle 10% , oxidation t...

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Abstract

The invention provides a device for implanting a degradable bone rod, comprising a degradable medical bone rod and a coating compounded on the surface of the medical bone rod; the medical bone rod is made of pure magnesium material or a magnesium alloy material, and the magnesium The alloy material includes: Fe greater than 0 and less than or equal to 0.5wt%, Zn greater than 0 and less than or equal to 1wt%, Mn greater than 0 and less than or equal to 0.6wt%, Cu greater than 0 and less than or equal to 0.05wt%, 0.8wt% % of Sr and the balance of Mg; the coating is a Ca-P-Ag coating. The present application also provides a preparation method of the degradable bone rod implantation device. This application adopts pure magnesium material or magnesium alloy material as the main body material of the degradable bone rod implantation device, and through the composite Ca-P-Ag coating on the surface of the main material, the degradable bone rod implantation device can induce new Bone grows in, rebuilds bone tissue, and achieves the purpose of repairing bone defects.

Description

technical field [0001] The invention relates to the technical field of medical bioimplantation materials, in particular to a degradable bone rod implantation device and a preparation method thereof. Background technique [0002] Biomedical materials are materials used to diagnose, treat, repair or replace damaged tissues and organs or enhance their functions; they are the basis for the study of artificial organs and medical devices, and have become an important branch of materials science today. Especially with the vigorous development and major breakthroughs of biotechnology, biomedical materials have become a hot spot for scientists from all over the world to research and develop. [0003] Biomedical materials can be divided into skeletal-muscular system repair materials such as bones, teeth, joints, and tendons, soft tissue materials such as skin, breast, esophagus, respiratory tract, and bladder, and cardiovascular systems such as artificial heart valves, blood vessels, ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L27/50A61L27/04A61L27/32A61L27/30A61L27/54C22C23/00C25D11/30
CPCA61L27/047A61L27/306A61L27/32A61L27/50A61L27/54A61L2300/102A61L2300/104A61L2300/112A61L2300/412A61L2430/02C22C23/00C25D11/024C25D11/026C25D11/30
Inventor 李扬德李卫荣滑有录刘芳菲
Owner DONGGUAN EONTEC CO LTD
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