A kind of preparation method and application of sensing electrode modified by graphene-single-wall carbon nanotube-nanometer cerium composite

Abstract

The invention relates to a graphene-single-wall carbon nano tube-nano cerium compound modified sensing electrode which comprises an electrode body and a modification article covering the electrode body, wherein the modification article comprises a compound of graphene, a single-wall carbon nano tube and nano cerium. The invention further relates to a preparation method and an application of the sensing electrode. An electrochemical sensor is assembled by replacing a conventional electrode with the graphene-single-wall carbon nano tube-nano cerium compound modified sensing electrode; and when metronidazole and ciprofloxacin in a solution is determined, two oxidation peaks with a very good separation degree can be obtained and have better peak shapes. Therefore, the preparation can be used for improving electrochemical determination accuracy.

Description

technical field [0001] The invention relates to a chemical quantitative determination technology, in particular to a sensing electrode of a high-sensitivity electrochemical sensor and its application. Background technique [0002] Metronidazole is a synthetic nitroimidazole derivative with broad-spectrum antibacterial activity and is effective in the treatment of diseases caused by anaerobic bacteria and protozoa. Ciprofloxacin is a synthetic third-generation quinolone antibacterial drug with broad-spectrum antibacterial activity and good bactericidal effect. It is widely used for infections of the respiratory system, urogenital system, digestive system and skin tissue structure. In recent years, metronidazole and ciprofloxacin have been gradually used in the human body, cosmetics, and livestock to achieve the functions of disease prevention, treatment, and health care and prevention. However, long-term low-dose use not only makes the drug remain in food, animals or the env...

AI Technical Summary

Problems solved by technology

But the sensing electrode of the electrochemical sensor used at present is the common glassy carbon electrode, carbon paste electrode etc. that the surface is not modified, there are following disadvantages when using these conventional electrodes to measure (see figure 1 shown): (1) Low sensitivity and poor resolution: when the electrochemical sensor with a conventional electrode is used to simultaneously measure metronidazole and ciprofloxacin in solution, the two oxidation peaks of metronidazole and ciprofloxacin occur partly Overlap phenomenon, the two peaks are not completely separated; (2) The peak shape is poor and the peak is not obvious: the oxidation peaks of metronidazole and ciprofloxacin have poor peak shape and poor peak shape symmetry, such as peak climbing before the peak and trailing after the peak and so on, which lead to inaccurate measurement results and large measurement errors

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