Stem cell ointment used for treating skin damages, and preparation method thereof

Abstract

The invention provides a stem cell ointment used for treating skin damages, and a preparation method thereof. The preparation method comprises following steps: mesenchymal stem cells with immunity adjusting and tissue regeneration promoting functions are prepared into blocks with uniform sizes under 3D suspension culture conditions, and are mixed with a biotoxicity-free active energy matrix so asto obtain the ointment. Stem cells are capable of living for as long as one week in the ointment at room temperature, and the biological activity is maintained. The stem cell ointment can be smeared onto skin damages directly, the stem cells in the ointment are capable of migrating into the wounds to inhibite inflammation, promote tissue regeneration, accelerate wound healing, improve healing status, and reducing scars; after restoration, the stem cells are eliminated by self immunity systems, no residual is left, the stem cell ointment is safe and stable, and is high in efficiency.

Description

technical field [0001] The invention relates to the field of cell biology, in particular to mixing stem cells with biologically active functions with a non-biotoxic matrix to make an ointment and a preparation method for the ointment. Background technique [0002] Acute and chronic wounds, such as various ulcers, ischemia-hypoxic wounds and burn residual wounds, endanger human health and affect the quality of life, and have become a huge problem in modern society. Due to the sharp increase in obesity, diabetes, and the aging population, the incidence of various skin injuries, especially chronic wounds, continues to rise. The treatment of these wounds consumes significant socioeconomic resources. The current means of wound treatment mainly include antibiotic intervention, surgery and negative pressure therapy. Although these treatments have made great progress, the healing rate of chronic wounds is still less than 50%. In the past two decades, stem cell research has made gr...

AI Technical Summary

Problems solved by technology

This method can partially improve wound healing, but because the low survival rate of single cells greatly affects the curative effect, how to improve the survival rate of cells after transplantation is the key to increasing the curative effect

There is an inflammatory environment in the wound, and the damaged blood vessels cause ischemia and hypoxia. It is difficult for conventionally cultured cells to adapt to such an environment. After transplantation, the high mortality rate often affects the curative effect

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