An endoscopic laser speckle blood flow imaging probe

A laser speckle and imaging probe technology, applied in blood flow measurement, medical science, diagnosis, etc., can solve the problems of inability to perform imaging, inability to measure blood flow and blood oxygen information, etc. uniform light effect

Active Publication Date: 2021-04-06
NANJING UNIV OF AERONAUTICS & ASTRONAUTICS
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, limited by the depth of light penetration, these techniques are only suitable for measuring blood flow in the cortex or retina, and cannot measure blood flow and blood oxygen information in lumens such as the digestive tract, and cannot be imaged

Method used

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  • An endoscopic laser speckle blood flow imaging probe
  • An endoscopic laser speckle blood flow imaging probe
  • An endoscopic laser speckle blood flow imaging probe

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Experimental program
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Effect test

Embodiment Construction

[0016] like figure 1 As shown, an endoscopic laser speckle blood flow imaging probe includes: eyepiece 1, focusing part 2, hose part 3, head end 4, joint adapter 5, cold light source interface 6, hose 7, transmission Like optical fiber 8, light-transmitting optical fiber 9, quartz optical fiber protective layer 10, quartz optical fiber 11, quartz optical fiber epitaxial part 12 and small lens 13; Through the adjustment of focusing part 2, a clear image is observed in the eyepiece 1 at the near end; One end of the endoscope body of the focusing part 2 is equipped with a joint adapter 5 for connecting a broadband light source, and the other end is equipped with a cold light source interface 6 for connecting a cold light source; the middle and lower part of the endoscope is a hose 7, and the hose Image transmission fiber 8 and light transmission fiber 9 for image transmission and light transmission, as well as silica fiber 11 for spectral experiments, are distributed inside. The ...

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Abstract

The invention discloses an endoscopic laser speckle blood flow imaging probe, comprising: an eyepiece, a focusing part, a hose part, a head end, a joint adapter, a cold light source interface, a hose, an image transmission fiber, and a light transmission fiber , silica fiber protective layer, silica fiber, epitaxial part of silica fiber and small lens. The invention combines the laser speckle blood flow imaging system with the endoscope to realize the blood flow detection of the digestive tract and other intracavitary organs; the number of light transmission optical fibers is increased in the probe, and four light transmission optical fibers surround the image transmission optical fibers , which increases the light-receiving area of ​​the tissue, makes the light more uniform and sufficient, and effectively avoids the appearance of spots; the invention combines laser speckle imaging and spectral detection, uses fiber lasers, provides laser light sources and broadband light sources, and realizes intracavity Simultaneous detection of organ blood flow and blood oxygen; Properly adjust the position of the image transmission fiber in the probe when designing the probe, overcome the defects of the original endoscopic detection, and realize the adherent measurement of blood flow.

Description

technical field [0001] The invention relates to the technical field of cavity endoscopy, in particular to an endoscopic laser speckle blood flow imaging probe. Background technique [0002] Blood flow and blood oxygen (SO 2 ) are two key parameters related to physiology. Measuring these parameters is important for monitoring, evaluating and understanding numerous diseases. Traditional methods of measuring blood flow are based purely on Doppler shift, OCT, ultrasound Doppler, angiography, and laser speckle contrast imaging (LASCA), which cannot measure blood oxygen saturation. SO 2 The detection of oxyhemoglobin and deoxyhemoglobin is usually based on the spectral detection method that has different absorption coefficients under different wavelengths of light, but pure multispectral imaging cannot provide blood flow velocity information. [0003] Compared with other existing blood flow monitoring methods, laser speckle blood flow imaging technology has the advantages of r...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/026A61B5/1455A61B5/00
CPCA61B5/0261A61B5/14551A61B5/14552A61B5/6847
Inventor 李韪韬赵月梅钱志余张雅檬薛彦柏
Owner NANJING UNIV OF AERONAUTICS & ASTRONAUTICS
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