Composition capable of reducing halitosis and application thereof

A composition and technology of bad breath, which are applied in the fields of medicine, microbiology and nutrition, can solve the problems such as oral bad breath or bad breath outside the mouth that are difficult to be completely treated, so as to improve the inflammation of the gastric mucosa, solve the problem of bad breath, and alleviate the problem of bad breath. The effect of gastritis

Active Publication Date: 2018-12-21
珠海中科先进技术研究院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, halitosis is usually caused by bacteria inside and outside the mouth, and it is difficult to obtain a thorough treatment effect if only a single treatment of oral halitosis or halitosi...

Method used

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  • Composition capable of reducing halitosis and application thereof
  • Composition capable of reducing halitosis and application thereof
  • Composition capable of reducing halitosis and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040]A probiotic composition for improving bad breath, containing 2 billion Lactobacillus salivarius, 1 billion Bifidobacterium bifidobacterium, 2 billion Lactobacillus johnsonii, 4 billion Lactobacillus rhamnosus, and Lactobacillus acidophilus per gram of the composition 2 billion, Lactobacillus reuteri 2 billion, Streptococcus salivarius 2 billion, Lactobacillus brevis 2 billion, xylitol content 280 mg, green tea powder 50 mg, yam powder 50 mg. The composition is in the form of buccal tablets and can be released in the oral cavity in a relatively short time.

[0041] human trials

[0042] Test process: 20 patients with true halitosis (12 males and 8 females; average age 42.3±8.9 years old, between 25 and 55 years old) were selected. These patients came to the clinic for the first time because of bad breath, and all patients voluntarily participated in the test. And did not take any antibiotics within three months before participating in the trial.

[0043] Test method: Th...

Embodiment 2

[0055] A probiotic composition for improving bad breath, containing 2.2 billion Lactobacillus salivarius, 1.3 billion Bifidobacterium bifidobacterium, 2.5 billion Lactobacillus johnsonii, 4.1 billion Lactobacillus rhamnosus, and Lactobacillus acidophilus per gram of the composition 2.5 billion, Lactobacillus reuteri 2 billion, Streptococcus salivarius 2 billion, Lactobacillus brevis 2 billion, xylitol content 300 mg, green tea powder 40 mg, yam powder 60 mg. The composition is in the form of buccal tablets and can be released in the oral cavity in a relatively short time.

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PUM

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Abstract

The invention discloses a composition capable of reducing halitosis and application thereof. The composition comprises composite probiotics, the composite probiotics comprise lactobacillus salivarius,bifidobacteria, lactobacillus rhamnosus, lactobacillus acidophilus, lactobacillus reuteri, streptococcus salivarius and lactobacillus johnsonii, wherein each gram of composition at least contains 2 billions of lactobacillus salivarius, 1 billions of bifidobacteria, 2 billions of lactobacillus johnsonii, 4 billions of lactobacillus rhamnosus, 2 billions of lactobacillus acidophilus, 2 billions oflactobacillus reuteri and 2 billions of streptococcus salivarius. The composition can also be widely applied in the preparation of drugs for treating halitosis, oral care products, cosmetic compositions, food or health-care products. Compared with the prior art, the composition disclosed by the solution of the invention can treat both intra-oral halitosis and extra-oral halitosis, and has the advantages of good therapeutic effect, broad application prospect and the like.

Description

technical field [0001] The invention relates to the fields of medicine, microbiology and nutrition, in particular to a composition capable of alleviating bad breath and its application. Background technique [0002] Bad breath is an unpleasant problem that can be caused by poor physical health or poor mental health. Halitosis patients usually dare not communicate with other people in close quarters, which has seriously affected people's normal social interaction and emotional communication. In addition, the World Health Organization (World Health Organization, WHO) has also regarded halitosis as a disease. According to relevant surveys, the prevalence of halitosis in China ranges as high as 22%-50%. [0003] Bad breath is usually caused by bacteria, which often release volatile sulfur compounds (Volatile Sulfur Compounds, VSCs) after decomposing sulfur-containing amino acids, including hydrogen sulfide, dimethyl sulfide, and methyl mercaptan. The occurrence of bad breath ...

Claims

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Application Information

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IPC IPC(8): A61K35/747A61K36/8945A61K8/99A61K8/9789A61K8/9794A61K8/9728A61K9/20A61K9/68A23L33/00A23G4/12A23G4/10A23G4/06A61P1/02A61P31/04A61Q11/00A61K35/744A61K35/745
CPCA61K36/8945A61P1/02A61P31/04A61Q11/00A23G4/068A23G4/10A23G4/123A23L33/00A61K8/9728A61K8/9789A61K8/9794A61K8/99A61K9/0056A61K9/0058A61K35/744A61K35/745A61K35/747A61K36/064A61K36/284A61K36/82A23V2400/151A23V2400/181A23V2400/113A23V2400/173A23V2400/245A23V2400/175A23V2400/51A61K2300/00
Inventor 谢苍桑
Owner 珠海中科先进技术研究院有限公司
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