Processing technology of radix bupleuri traditional Chinese medicine decocotion pieces

A technology for Chinese herbal decoction pieces and processing technology, which is applied in the directions of pharmaceutical formulations, medical preparations with non-active ingredients, plant raw materials, etc., can solve the problems of reducing the efficacy of Bupleurum chinensis, the loss of active ingredients, and the difference in the content of active ingredients, so as to improve the effective ingredients. The effect of content and side effect rate

Inactive Publication Date: 2019-03-08
CHANGSHA QIUDIANBING INFORMATION TECH CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] According to the Pharmacopoeia, Bupleurum must be made into decoction pieces before it can be used as a medicine. Therefore, the quality of Bupleurum decoction has a direct and significant impact on the curative effect and indications of the prescription, and the quality of Chinese patent medicines containing Bupleurum; long-term Since then, my country's traditional Chinese medicine processing market has been mixed with good and bad people, and the processing procedures for medicinal materials are also different, which has led to a gap in the content of active ingredients in the decoction pieces. Modern medicine has proved that the main active ingredients in Bupleurum include saikosaponin, Bupleurum volatile oil, Bupleurum flavonoids and stigmasterol and other substances, while the traditional processing of Bupleurum decoction pieces will lead to unnecessary loss of active ingredients and reduce the efficacy of Bupleurum
[0004] The Chinese patent with the application number CN201810370270.X discloses a method for making Bupleurum decoction pieces, including the steps of material selection, cleaning, soaking, slicing and drying, adding ingredients and stewing, continuous drying, sorting and packaging; the Bupleurum decoction pieces of the present invention The production method improves the content of active ingredients in traditional Bupleurum decoction pieces, reduces the residue of invalid impurities, enhances the quality of Bupleurum decoction pieces, and ensures the therapeutic effect of Bupleurum decoction pieces. However, the active ingredient content and performance of Bupleurum decoction pieces are still There is room for further improvement

Method used

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  • Processing technology of radix bupleuri traditional Chinese medicine decocotion pieces
  • Processing technology of radix bupleuri traditional Chinese medicine decocotion pieces

Examples

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Embodiment 1

[0025] A processing technology of Bupleurum traditional Chinese medicine decoction pieces, comprising: (1) selecting fresh Bupleurum plucked, removing residual stems and impurities, washing with clear water, and draining for later use; (2) adding the above-mentioned drained Bupleurum to EDTMPS aqueous solution After soaking for 2.5 hours, take out Bupleurum and rinse it repeatedly with running water for 3 times; (3) slice the above-washed Bupleurum, put it into a drying box and dry it for 35 minutes after slicing; (4) dry the dried Bupleurum Add 0.2 times the mass of rice vinegar to the Hu slices, then add 0.1 times the mass of ethanol solution, and simmer until the solution is completely absorbed; (5) continue to add 0.1 times the mass of rice wine to the above-mentioned Bupleurum slices, and then add Hawthorn juice, enzyme stock solution, and carbonic acid in a total amount of 0.2 parts by mass continue to be boiled until the solution is fully absorbed; the mass ratio of the ...

Embodiment 2

[0028]A processing technology of Bupleurum traditional Chinese medicine decoction pieces, comprising: (1) selecting fresh Bupleurum plucked, removing residual stems and impurities, washing with clear water, and draining for later use; (2) adding the above-mentioned drained Bupleurum to EDTMPS aqueous solution After soaking in water for 2 hours, take out Bupleurum and rinse it with running water for 4 times; (3) slice the washed Bupleurum into slices, and put them in a drying box to dry for 30 minutes; (4) dry the dried Bupleurum Add 0.2 times the weight of rice vinegar to the slices, then add 0.1 times the weight of ethanol solution, and cook until the solution is completely absorbed; Measure the hawthorn juice, enzyme stock solution, and carbonic acid of 0.2 parts by mass, and continue to stew until the solution is fully absorbed; the mass ratio of the hawthorn juice, enzyme stock solution, and carbonic acid is 00.06:0.01:0.05; (6) combine the above steps (5) Take out the Bup...

Embodiment 3

[0031] A processing technology of Bupleurum traditional Chinese medicine decoction pieces, comprising: (1) selecting fresh Bupleurum plucked, removing residual stems and impurities, washing with clear water, and draining for later use; (2) adding the above-mentioned drained Bupleurum to EDTMPS aqueous solution After soaking in water for 3 hours, take out Bupleurum, and rinse it repeatedly with running water for 3 times; (3) slice the washed Bupleurum, put it into a drying box and dry it for 40 minutes after slicing; (4) dry the dried Bupleurum Add 0.2 times the weight of rice vinegar to the slices, then add 0.1 times the weight of ethanol solution, and cook until the solution is completely absorbed; Measure the hawthorn juice, enzyme stock solution, and carbonic acid of 0.2 parts by mass, and continue to stew until the solution is fully absorbed; the mass ratio of the hawthorn juice, enzyme stock solution, and carbonic acid is 0.04:0.02:0.03; (6) combine the above steps (5) Ta...

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Abstract

The invention discloses a processing technology of radix bupleuri traditional Chinese medicine decocotion pieces. The processing technology comprises the following steps: (1) selecting and picking fresh radix bupleuri; (2) soaking the radix bupleuri in an EDTMPS (Ethylenediamine Tetramethylphosphonate Sodium) water solution for 2 to 3 hours; (3) slicing the radix bupleuri, and drying; (4) adding the dried radix bupleuri pieces in rice vinegar accounting for 0.2 time of the dried radix bupleuri in parts by mass, then adding an ethanol solution accounting for 0.1 time in parts by mass, and braising until completely absorbing the solution; (5) continuously adding yellow rice wine accounting for 0.1 time in parts by mass, then adding haw juice, ferment stoste and carbonic acid accounting for 0.2 time of the total amount in parts by mass, and continuously braising until completely absorbing the solution; wherein a mass ratio of the haw juice to the ferment stoste to the carbonic acid is (0.04 to 0.06):(0.01 to 0.02):(0.03 to 0.05); (6) drying and sorting, and packaging, thus obtaining a finished product-radix bupleuri decoction pieces. According to the processing technology disclosed bythe invention, by adopting the haw juice, the ferment stoste and the carbonic acid as a reinforcement system, the content and the side effect rate of effective components of the radix bupleuri traditional Chinese medicine decocotion pieces can be increased.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a processing technology for decoction pieces of Bupleurum bupleuri. Background technique [0002] Bupleurum, also known as Dixun, Shancai, Mushroom, and Firewood, is a traditional Chinese medicinal material. The medicinal part is the dried root of Bupleurum or Bupleurum narrow leaves, which has the effect of reconciling the exterior and interior, soothing the liver and promoting yang. For cold and fever, alternating cold and heat, malaria, liver depression and Qi stagnation, sternocostal pain, anal prolapse, uterine prolapse, and irregular menstruation. [0003] According to the Pharmacopoeia, Bupleurum must be made into decoction pieces before it can be used as a medicine. Therefore, the quality of Bupleurum decoction has a direct and significant impact on the curative effect and indications of the prescription, and the quality of Chinese patent...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/233A61K47/04A61K36/734A61K125/00
CPCA61K36/233A61K36/73A61K36/734A61K47/02A61K2236/13A61K2236/15A61K2236/17A61K2300/00
Inventor 不公告发明人
Owner CHANGSHA QIUDIANBING INFORMATION TECH CO LTD
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