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A composition for preventing or improving circadian rhythm disorders

A circadian rhythm and composition technology, which is applied in the field of cosmetics, pharmaceutical compositions and food compositions to prevent or improve circadian rhythm disorders, can solve problems that have not been studied before, and achieve no toxicity, side effects, and circadian rhythm disorders prevention or improvement

Pending Publication Date: 2019-03-19
韩国百鸥思特公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] However, so far, almost no studies have been conducted on the biological rhythm regulation function and the prevention and improvement or therapeutic effects of circadian disorders

Method used

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  • A composition for preventing or improving circadian rhythm disorders
  • A composition for preventing or improving circadian rhythm disorders
  • A composition for preventing or improving circadian rhythm disorders

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0060] Embodiment 1: the preparation of the extracts of Prunus edulis, iron broom and broad-leafed peduncle

[0061] The sage tree, leaf-cutting iron broom and sagebrush are produced in Jeju. The whole plant is collected from leaves to roots, dried in the air at 20°C to 35°C, and crushed so that the crushed particles are less than 1mm. Then, 1 kg of the pulverized powder was put into a 70% ethanol solvent, ultrasonic extraction was performed at 70° C. for 48 hours, and the obtained extract was filtered with filter paper (Advantes, No. 2). Then, concentration under reduced pressure is carried out to prepare the extracts of Fructus Prunebrae, Prunus chinensis and Prunus euphratica.

preparation example 1

[0068] Preparation Example 1: Cosmetic preparation

[0069] 1-1. Toner

[0070] 【Table 1】

[0071] Element

weight%

ramie extract

0.05

Glycerol

3.0

Butanediol

2.0

Propylene Glycol

2.0

carbomer

0.1

ethanol

10.0

Triethanolamine

0.1

Preservatives, trace pigments, trace spices and trace purified water

82.74

total

100.0

[0072] 1-2. Nutritious lotion

[0073] 【Table 2】

[0074]

[0075]

[0076] 1-3. Nutritional cream

[0077] 【table 3】

[0078] Element

weight%

ramie extract

0.05

yellow wax

10.0

Polysorbate 60

1.5

Sorbitan Sesquioleate

0.5

liquid paraffin

10.0

Squalane

5.0

Caprylic / Capric Glycerides

5.0

Glycerol

5.0

Butanediol

3.0

Propylene Glycol

3.0

Triethanolamine

0.2

Preservatives, trace pigments, trace spices and trace purified water...

preparation example 2

[0086] Preparation Example 2: Pharmaceutical preparation

[0087] 2-1. Preparation of powder

[0088] 【Table 6】

[0089] Element

[0090] After mixing the above ingredients, it was filled in an airtight cloth and a powder was prepared.

[0091] 2-2. Preparation of tablet

[0092] 【Table 7】

[0093] Element

[0094] After mixing the above-mentioned components, tableting was performed according to a usual method for preparing tablets to prepare tablets.

[0095] 2-3. Preparation of capsules

[0096] 【Table 8】

[0097] Element

[0098] After mixing the above-mentioned ingredients, according to the usual preparation method for preparing capsules, filling them in gelatin capsules to prepare capsules.

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PUM

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Abstract

The present invention relates to a composition used for preventing or reducing circadian rhythm disorders and comprising a Lespedeza plant extract as an active ingredient, wherein the composition enhances the biological clock rhythmicity, and can be usefully used as a composition capable of improving, preventing or treating skin damage caused by the biorhythm disorders through the action. In addition, the Lespedeza plant extract is a chemical substance derived from plants and is safe as the Lespedeza plant extract has little side effects on the human body, thereby being safely applied to cosmetics, pharmaceuticals and food compositions.

Description

technical field [0001] The present invention relates to a composition for preventing or improving circadian rhythm disorder containing an extract of a plant of the genus Lespedeza (Lespedeza sp.) as an active ingredient, and more particularly, relates to an extract of a plant of the genus Lespedeza sp. Cosmetics, pharmaceutical compositions and food compositions for preventing or improving circadian rhythm disorders. Background technique [0002] Most living organisms, including mammals, have a cycle of about 24 hours by adapting to changes in day and night, which is called a "biological clock". In order to adapt to repeated changes in the external environment, living organisms have continuously strengthened the internal cycle timing mechanism. That is, the coordination of life processes in the body can be carried out in a timely manner with changes in the external environment. The biological clock is synchronized with the external environment through external signals such...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/48A61P43/00A61Q19/00
CPCA23L33/105A61K8/97A61K36/48A61Q19/00A23V2002/00A23V2250/21A61Q19/08A61K8/9789A61P43/00A23V2200/318A61K9/0014
Inventor 廉美智郑恩先朴德勋
Owner 韩国百鸥思特公司
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