Preparation method of GO (Graphene Oxide)/NiCO LDHs catalytic material for detecting glucose and electrochemical sensor

Abstract

The invention discloses a preparation method of a GO (Graphene Oxide) / NiCO LDHs catalytic material for detecting glucose and an electrochemical sensor. The preparation method comprises the following steps: firstly, dispersing graphene oxide (GO) into absolute methanol to obtain a graphene oxide dispersion solution; synthesizing GO@ZIF-67 by utilizing cobalt nitrate hexahydrate and dimethylimidazole; then carrying out hydrothermal synthesis on the GO@ZIF-67 and the nickel nitrate hexahydrate to obtain the GO / NiCO LDHs catalytic material; finally, dropwise adding a catalytic material solution onto a cleaned bare glass carbon electrode, so as to obtain a GO / NiCO LDHs modified electrochemical sensor. According to the preparation method, good electrochemical performance of the graphene oxide, and a porous structure and a regular shape of an MOFs (Metal Organic Frameworks) material are combined; ZIF-67 is used as a sacrificial template and oriented growth of the NiCO LDHs catalytic materialis realized; the stability of the glucose electrochemical sensor is enhanced, a detection range is expanded, the detection cost is reduced and the sensitivity of detection is improved. An enzyme-freeelectrochemical sensor makes a breakthrough of improving the analytical performance including high stability, high sensitivity and high catalytic performance and.

Description

technical field [0001] The present invention relates to the technical field of electrochemical sensors, in particular to the field of enzyme-free glucose detection, in particular to a GO / NiCO LDHs catalytic material for glucose detection and a method for preparing an electrochemical sensor, which has been successfully applied to the detection of blood glucose concentration in humans. The invention belongs to the technical field of functional materials and electrochemical sensors. Background technique [0002] Glucose is the most common substance in daily life. It is of great significance to quickly and accurately analyze and detect its content in many fields such as clinical testing of diabetic patients and food industry. Undoubtedly, the development of an ideal glucose sensor must become the primary issue of the sensor industry, and there are many methods for detecting glucose. For example, high performance liquid chromatography, spectrophotometry, optical rotation, gas ch...

AI Technical Summary

Problems solved by technology

[0006] In recent years, glucose sensors have been a hot topic of research by scholars. Glucose sensors are divided into enzyme sensors and enzyme-free electrochemical sensors. The stability and importance of enzyme sensors are relatively poor, mainly due to the fact that the enzyme itself is easily affected by the environment. Moreover, the price is expensive and the immobilization process is complicated. These shortcomings restrict the application range of enzyme sensors to a certain extent, making the research of enzyme-free electrochemical sensors very important, and the key to their performance lies in the development and application of electrode modification materials. The emergence of nanomaterials will play an inestimable role in the progress of sensors