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Traditional Chinese medicine compound preparation with whitening effect and preparation method of traditional Chinese medicine compound preparation

A technology of compound preparation and traditional Chinese medicine, which is applied in the field of Chinese medicine compound preparation with whitening effect and its preparation, which can solve the problems of thinning of skin stratum corneum, large side effects of hydrogen, skin pigmentation, etc. Minimizes and dilutes the effect of pigmentation

Inactive Publication Date: 2019-03-29
FOSHAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, most of the existing whitening products are prepared by adding salicylic acid and other softening cuticles to promote the metabolism of cuticles, and then adding fluorescent skin brightening factors that directly whiten. Although these products can whiten the skin in a short period of time , but this way of accelerating the metabolism of the stratum corneum tends to make the stratum corneum thinner and the skin is sensitive; while the whitening effect of hydrogen kun is very good, but the side effects of hydrogen kun are too large and it is forbidden; kojic acid and its derivatives have strong whitening effect , but it is easy to decompose when exposed to light and heat. Whitening preparations containing chemical ingredients or heavy metals are likely to cause skin pigmentation after use, and the side effects are relatively large

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] A traditional Chinese medicine compound preparation with whitening effect. The traditional Chinese medicine compound preparation comprises the following components in parts by weight: 20 parts of pearl powder, 10 parts of barley, 25 parts of white fungus, 5 parts of Centella asiatica, 10-20 parts of perilla 20 parts, 20 parts of Atractylodes macrocephala, 20 parts of red dates, and the particle diameter of the pearl powder is 200-300nm.

[0027] A preparation method of a traditional Chinese medicine compound preparation with whitening effect, comprising the following steps:

[0028] (1) According to the composition ratio described in claim 1 or claim 2, take white fungus, barley, perilla, centella asiatica, atractylodes macrocephala, and red dates and grind them into fine powders for subsequent use, then add extraction solvent to reflux to extract 2 to 4 times, reflux each time for 1 to 3 hours, combine the extracts, filter, remove the filtrate, concentrate the medicina...

Embodiment 2

[0035] A traditional Chinese medicine compound preparation with whitening effect. The traditional Chinese medicine compound preparation comprises the following components in parts by weight: 30 parts of pearl powder, 25 parts of barley, 45 parts of white fungus, 15 parts of Centella asiatica, 15 parts of perilla, 25 parts of Atractylodes macrocephala, 25 parts of red dates, and the particle size of the pearl powder is 200-300nm.

[0036] The preparation method of the traditional Chinese medicine compound preparation described in Example 2 is the same as that described in Example 1.

[0037] Select 90 women aged 26 to 40 with an average age of 35. The patients showed dark, yellow, and pigmented skin on their faces; they were randomly divided into 2 groups: Example 1 and Example 2. Example 1 group used the medicament prepared in Example 1, and Example 2 group used the medicament prepared in Example 2, and applied it to the whole face every night for 28 consecutive days.

[0038...

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Abstract

The invention discloses a traditional Chinese medicine compound preparation with a whitening effect and a preparation method of the traditional Chinese medicine compound preparation. The traditional Chinese medicine compound preparation comprises the following components in parts by weight: 20-40 parts of pearl powder, 10-30 parts of coix seeds, 25-60 parts of white fungus, 5-20 parts of herba centellae, 10-20 parts of purple common perilla, 20-25 parts of bighead atractylodes rhizome and 20-25 parts of red dates. The traditional Chinese medicine compound preparation well inhibits melanin generation and weakens pigmentation. In addition, the traditional Chinese medicine compound preparation comprises various traditional Chinese medicine active ingredients, can effectively promote metabolism of skin and is low in skin irritation.

Description

technical field [0001] The technical solution belongs to the technical field of traditional Chinese medicine preparations, in particular to a compound traditional Chinese medicine preparation with whitening effect and a preparation method thereof. Background technique [0002] The mechanism of skin melanin formation is mainly as follows: the formation process of melanin, the tyrosine in melanocyte tissue passes through dopa, dopaquinone, dopachrome and dihydroxylation under the action of enzymes such as tyrosinase. Intermediates such as indole are gradually converted into eumelanin, and then the melanocyte tissue transfers the melanin to the basal layer cells of the epidermis, and is brought to the stratum corneum with the metabolism of the cells, and finally falls off with the keratinocytes. However, due to the influence of ultraviolet rays, genetics, endocrine, inflammatory mediators, improper diet and other factors, melanin metabolism is abnormal, and skin melanin grows t...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61P17/00A61K35/618
CPCA61K35/618A61K36/07A61K36/23A61K36/284A61K36/535A61K36/725A61K36/8994A61K2236/331A61K2236/39A61K2236/51A61P17/00A61K2300/00
Inventor 谢海青谢君毅
Owner FOSHAN UNIVERSITY