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Composition for hangover including milk thistle, turmeric, and glycyrrhizae radix and Cassiae Semen

A composition, the technology of milk thistle, applied in the field of hangover digestion composition, can solve the problems of low activity, health problems, low alcohol decomposition efficiency, etc., and achieve the effect of liver toxicity protection and excellent inhibition effect

Active Publication Date: 2019-04-05
주식회사하이웰디앤에이치
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In particular, it is well known that Asians such as Koreans, Chinese, or Japanese have lower activity of alcohol-decomposing enzymes than Westerners, so the efficiency of alcohol-decomposing alcohol is low, and it is true that the health problems caused by non-metabolized alcohol are serious

Method used

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  • Composition for hangover including milk thistle, turmeric, and glycyrrhizae radix and Cassiae Semen
  • Composition for hangover including milk thistle, turmeric, and glycyrrhizae radix and Cassiae Semen
  • Composition for hangover including milk thistle, turmeric, and glycyrrhizae radix and Cassiae Semen

Examples

Experimental program
Comparison scheme
Effect test

experiment example

[0039] Experimental example: evaluation of ethanol and acetaldehyde decomposition effect

[0040] (1) Experimental materials

[0041] In order to evaluate the effects of various test substances in the process of ethanol metabolism associated with hangovers, the following experiments were carried out. As experimental materials, ethanol (Merck; Item code: 1.00983.0511-500ML) and acetaldehyde (Source: Sigma; Cat No.: 402788-5ML) were used.

[0042] As the experimental animals, 8 male Wistar rats (Albi no Wistar rats, Rattus norvegicus) with a body weight of 245-260 g were used in each group. Experimental animals were acclimatized to the experimental conditions for one week before being administered ethanol.

[0043] Initial random selection was based on recent body weight. Only animals with individual body weights within ±20% of the group mean were used. Animals are identified by dilute picric acid solution and caged cards. Animals were identified by cage cards and animal id...

manufacture example

[0079] Production example: Production of composition for hangover relief

[0080] In order to manufacture the hangover resolving composition, milk thistle, turmeric, licorice, and cassia seeds were prepared as active ingredients by the following methods, respectively.

[0081] Extract and filter Cassia tora leaves with water at 90-95° C., wash the filtrate, and concentrate with 25-30% T.S at NMT 70° C. under vacuum at 450-550 mmHg. Thereafter, after spray-drying at an inlet (Inlet) temperature of 160° C. to 175° C. and an outlet (Outlet) temperature of 105° C. to 115° C., it was pulverized and sieved (sieve). Glycyrrhiza glabra roots were also extracted by the same method as Cassia cotyledons.

[0082] The curcuma longa rhizomes (Curcuma longa rhizomes) were extracted and filtered by ethanol at 75-80°C, and the filtrate was washed and then concentrated by 50-60% T.S at NMT 70°C under vacuum at 450-550mmHg. Thereafter, at a temperature of NMT 80° C., vacuum drying was perform...

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PUM

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Abstract

The present invention relates to the composition for hangover including the milk thistle, turmeric, and the glycyrrhizae radix and Cassiae Semen, and the disassembly effect of ethanol and acetaldehydeis remarkably excellent among blood and the composition for hangover of the invention exhibits the synergistic effect in hangover. Moreover, the function improvement effect which effectively protectsthe cell going about the hepatotoxicity in which the compound for improving liver function of the invention is caused by ethanol is remarkably excellent.

Description

technical field [0001] The present invention relates to a composition for hangover containing Silybum marianum, Curcumalonga, Glycyrrhiza glabra and Cassia tora, which has a remarkably excellent hangover resolution effect by decomposing acetaldehyde and ethanol in blood. Background technique [0002] According to clinical symptoms, alcoholic liver disease can be divided into alcoholic fatty liver, alcoholic hepatitis, and alcoholic cirrhosis, which generally occurs when 60-80g of alcohol is consumed daily for about 10 years. Alcoholic fatty liver is caused by the accumulation of cholesterol and neutral fat in the liver cells due to excessive intake of alcohol. It can be recovered immediately as long as you stop drinking, but if you continue to drink, it will develop into hepatitis. Alcoholic hepatitis is a state in which necrosis and inflammation of liver cells occur, and various symptoms such as fatigue, loss of appetite, weight loss, jaundice, fever, or pain in the upper r...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P1/16A61P39/02
CPCA61K36/9066A61P1/16A61P39/02A61K36/28A61K36/482A61K36/484A23L33/105A23V2200/334A23V2002/00
Inventor 尹大重
Owner 주식회사하이웰디앤에이치
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