44 results about "Ethanol metabolism" patented technology

The invention provides application of a lactobacillus mucus fermentation strain A21196 in preparation of a product for promoting ethanol metabolism, and belongs to the technical field of microbial preparations. The lactobacillus mucus fermentation strain A21196 has the high-yield ethanol dehydrogenase and acetaldehyde dehydrogenase, and has the effects of reducing the content of ethanol and acetaldehyde in the blood of mice suffering from acute alcoholism and shortening the central nervous inhibition time in vivo. Therefore, the invention provides the application of the fermented lactobacillus mucus strain A21196 in preparation of a product for preventing and / or treating the alcoholic liver injury or the alcoholic liver disease.

The invention discloses a Lactobacillus paracasei grx06 and an application thereof in the aspects of dispelling the effects of alcohol and protecting the liver, the strain number of the Lactobacillus paracasei is grx06, the Lactobacillus paracasei is preserved in the China General Microbiological Culture Collection Center on February 18, 2025, and the preservation number is CGMCC No: 33560. The lactobacillus paracasei obtained by screening in the invention has the capability of producing ethanol dehydrogenase and acetaldehyde dehydrogenase at high yield, and is high in ethanol tolerance. In addition, the traditional Chinese medicine composition has the effects of promoting ethanol metabolism in rats and recovering liver injury. Wide application prospects are realized in the field of anti-alcohol and liver-protecting products.

The invention provides a probiotic composition for promoting ethanol metabolism as well as a probiotic agent and application thereof, and belongs to the technical field of biological medicines. The preparation method comprises the following steps: compounding lactobacillus mucus A21252, plant lactobacillus A21352, casei paracasei A21151 and lactobacillus reuteri A21325 to obtain a probiotic composition, and matching the probiotic composition with auxiliary materials (resistant dextrin, xylooligosaccharide, erythritol, L-arabinose, lemon fruit powder and corn oligopeptide powder) to obtain the probiotic agent. The probiotic agent not only can quickly improve the hangover alleviating speed, has the effects of alleviating hangover, protecting liver and eliminating gastrointestinal dysfunction caused by alcoholism, but also can reduce discomfort caused by excessive drinking. The probiotic agent is simple and convenient to process, low in cost and wide in market prospect.

The invention discloses an application of plant starch in preparation of a product for dispelling effects of alcohol and protecting liver. The golden sweet potato starch can be effectively used for dispelling the effects of alcohol and protecting the liver for the first time, the activity of key enzymes ADH and ALDH in an ethanol metabolism path is enhanced, the in-vivo ethanol metabolism speed is increased, liver damage caused by drunkenness is relieved, the golden sweet potato starch has the body protection effect, meanwhile, the drunkenness rate can be reduced, the drunkenness time can be shortened, the content of ALT, AST, TC, TG and LDL-C in the body can be remarkably reduced, and the anti-alcohol effect is achieved. According to the invention, the content of HDL-C is increased, the activity of CAT, SOD and GSH in the liver of the organism is remarkably improved, the MDA level of the liver is reduced, the fat accumulation condition of the liver of the organism is remarkably improved, and a new direction is provided for preparation of products for dispelling the effects of alcohol and protecting the liver.

The invention belongs to the technical field of medicines, and particularly relates to a plant lactobacillus for relieving acute alcoholic liver injury as well as a metagen and application of the plant lactobacillus. The strain of the plant lactobacillus L5-13 is preserved in the China Center for Type Culture Collection on August 18, 2025, and the preservation number of the strain is CCTCC NO: M 20251835. The strain and the metagen thereof can significantly improve pathological symptoms of mice with acute alcoholic liver injury, including: reducing the levels of ALT, AST, TC, TG and LDL-C in serum of the mice with acute alcoholic liver injury, and increasing the level of HDL-C; the abnormal blood lipid level of the mouse caused by acute alcohol is regulated; the activity of antioxidant enzymes in the liver is improved, and the lipid peroxidation level is reduced; the ethanol dehydrogenase activity of the liver is improved, and the ethanol metabolism capability is enhanced. Therefore, the strain and the metagen thereof have wide application prospects in prevention or treatment of acute alcoholic liver injury.

The invention relates to the technical field of traditional Chinese medicines, in particular to a hangover-alleviating, liver-protecting and stomach-protecting agent and a preparation method thereof. The alcohol effect dispelling, liver protecting and stomach protecting agent is prepared from the following raw material components in parts by mass: 1-10 parts of peristrophe japonica, 1-10 parts of penthorum chinense pursh, 1-10 parts of flos puerariae, 1-10 parts of radix puerariae, 1-10 parts of lalang grass rhizome, 1-10 parts of hovenia dulcis thunb and 1-5 parts of taurine. The traditional Chinese medicine composition has better hangover-alleviating and liver-protecting effects, obviously shortens the hangover-alleviating and sobering time, is taken before drinking, takes effect faster, has the effects of alleviating hangover, inducing resuscitation, strengthening the spleen and stomach, calming the adverse-rising energy, arresting vomiting and protecting the liver, reduces AST and ALT in human serum, can enhance the activity of ethanol dehydrogenase and acetaldehyde dehydrogenase in the human liver, and promotes ethanol metabolism.

The invention discloses a construction method and application of Kluyveromyces marxianus capable of producing succinic acid, and belongs to the technical field of biology. According to the invention, an ethanol metabolism pathway gene PDC1 is knocked out, succinic acid reduction synthesis pathway related genes are overexpressed in cells, the PDC1 gene is knocked out by adopting a CRISPR-Cas9 technology, overexpression of the pathway gene in the cells is realized by adopting an NHEJ technology, and an excellent strain for high yield of succinic acid is constructed. After the strain constructed by the invention is subjected to fed-batch fermentation culture in a 5L fermentation tank, the yield of succinic acid reaches 42.9 g / L, and the conversion rate reaches 0.37 g / g glucose. The strain constructed by the invention has a good application prospect in the fields of chemical engineering, degradable materials and food.

The invention relates to the technical field of pharmaceutical compositions, and particularly discloses a proteolipid composite supplement with synergistic hangover alleviating and liver protecting functions and a preparation method thereof. The health-care food comprises the following components in percentage by mass: 10-25% of a Pu'er tea extract, 15-30% of glucose syrup, 5-15% of a hovenia acerba extract, 5-15% of a radix puerariae extract, 8-20% of corn peptide, 5-15% of oyster peptide, 3-10% of earthworm peptide, 1-5% of malic acid, 2-8% of multivitamins, 1-5% of an electrolyte compound, 3-10% of prebiotic fibers and 0.5-3% of gamma-aminobutyric acid. The compound vitamins comprise B1, B2, B6, B12, folic acid and vitamin C; the electrolyte compound is a nanoscale electrolyte compound and is an organic chelate containing potassium, magnesium and zinc; the prebiotic fiber is prepared by compounding galactooligosaccharide and resistant dextrin; through compounding design of active peptide components, plant active ingredients and functional factors, the active peptide improves the activity of key enzymes in ethanol metabolism in a targeted manner, and alcohol decomposition is accelerated.

The invention relates to the technical field of microorganisms, in particular to application of lactobacillus paracasei ZJUIDS05 (CGMCC (China General Microbiological Culture Collection Center) NO.20515) in preparation of a medicine for improving alcohol metabolism and alcoholic liver diseases. When the ZJUIDS05 is used for improving alcohol metabolism, the ZJUIDS05 can be used for reducing the ethanol content, ALT and AST in plasma; the metabolic capability and the oxidation resistance of the ethanol are enhanced; when the ZJUIDS05 intervention is used for improving alcoholic liver diseases, liver injury (ALT and AST levels are remarkably reduced) caused by alcohol can be remarkably improved, the content of ethanol in plasma is reduced, and the metabolic capacity and the antioxidant capacity of ethanol are enhanced.

The invention relates to the technical field of health food, in particular to a selenium tea ethanol dehydrogenase activating peptide composition as well as a preparation method and application thereof. A response surface method is adopted to optimize a TSE-PP preparation process, affinity ultrafiltration and LC-MS / MS technologies are utilized to screen ADH binding peptides, and the action mechanism of the ADH binding peptides is researched through molecular docking and animal experiments. Experiments prove that the TSE-PP can promote ethanol metabolism, relieve liver cell injury, inhibit inflammatory response, relieve oxidative stress and improve liver lipid accumulation, the high-dose use effect is more remarkable, and a scientific basis is provided for application of the TSE-PP in the food with the function of dispelling the effects of alcohol and the nutrition fortified product. The invention discloses the preparation process of the TSE-PP and the anti-alcohol and liver protection effects of the TSE-PP, meanwhile, the TSE-PP has good food processing characteristics, and a theoretical basis and an experimental support are provided for production and application of the TSE-PP in functional foods.

The invention discloses a rosa roxburghii tratt fruit composite beverage with a hangover alleviating effect and a preparation method and application thereof, and belongs to the technical field of biology. The roxburgh rose beverage disclosed by the invention comprises the following raw materials in parts by weight on the basis of 100 parts by weight: 8-16 parts of roxburgh rose concentrated juice, 5-15 parts of crystalline fructose, 0.8-2.5 parts of soybean peptide powder, 0.8-1.8 parts of yeast extract and the balance of water. Experiments prove that the formula product has the advantages of moderate taste, aromatic flavor, good stability and the like, and can keep stable taste and flavor during long-term storage. Animal experiments verify that the roxburgh rose beverage has an obvious hangover alleviating effect by improving ALDH activity, accelerating ethanol metabolism and reducing blood ethanol mass concentration, can improve liver injury caused by drinking by increasing liver SOD, GSH-Px, CAT activity and GSH content, reducing MDA content, enhancing body antioxidant ability and inhibiting lipid peroxidation reaction, and has a liver protection effect.

The invention discloses a medicinal and edible composition which is characterized by comprising the following components in parts by weight: 15-20 parts of a hovenia dulcis thunb extract, 10-15 parts of a turmeric extract, 8-12 parts of a schisandra chinensis extract, 5-8 parts of a globe artichoke extract, 6-10 parts of a ganoderma lucidum spore powder extract and 0.5-1 part of a silibinin extract. According to the composite composition prepared by the invention, ethanol metabolism key enzyme (ADH / ALDH) is activated by multiple targets, acetaldehyde removal is accelerated, and a hepatocyte repairing function is supplemented, so that alcohol metabolism after drinking is accelerated, and damage of alcohol to a human body is reduced.

The invention provides application of lactobacillus brevicornu and a fermentation composition thereof in hangover alleviating and liver protection, and relates to the technical field of biological fermentation, the lactobacillus brevicornu is lactobacillus brevicornu, the strain number of the lactobacillus brevicornu is KMHD10-222, and the registration number of the lactobacillus brevicornu in the China General Microbiological Culture Collection Center is CGMCC No. 32358. Traditional Chinese medicine substrates can be fermented, and the hangover-alleviating and liver-protecting effects of fermentation products are enhanced. The content of rare ginsenoside, total polysaccharide, total flavone, total phenol, puerarin, daidzein and dihydromyricetin of the lactobacillus brevis KMHD10-222 fermentation substrate extracting solution is increased, the effects of promoting ethanol metabolism and improving the alcoholic liver disease can be improved, and the effects of dispelling the effects of alcohol and protecting the liver are achieved.

The invention relates to the technical field of medicines, in particular to a composition for relieving headache after drinking and a preparation method thereof. Comprising the following raw materials in parts by weight: 5-10 parts of curcumin composite particles, 20-30 parts of a chitosan stable fermentation liquid, 10-15 parts of a radix puerariae extract, 5-10 parts of an emblic leafflower fruit extract, 10-15 parts of Chinese wolfberry fruits, 5-10 parts of cassia seeds, 5-10 parts of smoked plums, 5-10 parts of a roselle extract, 10-15 parts of a sweetening agent and 5-8 parts of a stabilizer. Wherein the curcumin composite particles are prepared through nano-liposome embedding and tannic acid and polyethylene glycol functionalization treatment, the chitosan stable fermentation liquor is prepared by compounding chitosan and red pitaya fermentation liquor, and the composition is prepared through the processes of plant component extraction, mixing and blending, sterilization treatment and the like. Ethanol metabolism can be accelerated, and the antioxidant capacity of the liver is enhanced, so that damage of alcohol to the liver is relieved, and headache after drinking is effectively relieved.

The invention provides a polypeptide and application thereof. The polypeptide with the amino acid sequence as shown in SEQ ID NO: 1 not only can remarkably remove ABTS free radicals and DPPH free radicals and play a role in resisting oxidation, but also can activate ADH enzyme and ALDH enzyme and play a role in promoting ethanol metabolism, so that the alcoholic liver disease is effectively resisted.

The invention belongs to the technical field of medicines, and particularly relates to lactobacillus rhamnosus for relieving acute alcoholic liver injury as well as a metagen and application of the lactobacillus rhamnosus. The lactobacillus rhamnosus L11-4 strain is preserved in the China Center for Type Culture Collection on August 18, 2025, and the preservation number of the lactobacillus rhamnosus L11-4 strain is CCTCC (China Center for Type Culture Collection) NO: M 20251834. The strain and the metagen thereof can significantly improve pathological symptoms of mice with acute alcoholic liver injury, and have the effects of reducing the levels of ALT, AST, TC, TG and LDL-C in serum of the mice with acute alcoholic liver injury, increasing the level of HDL-C, and regulating abnormal blood lipid level of the mice caused by acute alcohol; the activity of antioxidant enzymes in the liver is improved, and the lipid peroxidation level is reduced; in addition, the ethanol dehydrogenase activity of the liver can be improved, and the ethanol metabolism capability is enhanced. Therefore, the strain and the metagen thereof have wide application prospects in prevention or treatment of acute alcoholic liver injury.

The invention discloses a pyruvic acid gene loop mediated saccharomyces cerevisiae ethanol metabolism redirection method. Comprising the following steps: constructing a pyruvic acid response gene loop in saccharomyces cerevisiae host bacteria to obtain modified saccharomyces cerevisiae; the growth of saccharomyces cerevisiae cells, the synthesis of by-product ethanol and the synthesis of products are dynamically regulated and modified by controlling glucose feeding. A low-concentration glucose environment is maintained in the early stage of growth, so that cell growth and ethanol metabolism related genes are normally expressed, and cell growth is recovered; high-concentration glucose is supplemented in the later stage of fermentation, expression of cell growth related ethanol metabolism genes is inhibited, the ethanol synthesis flux is reduced, sufficient pyruvic acid precursors are provided for product synthesis, and the product synthesis flux is maximized. According to the method, the yield of the byproduct ethanol is reduced, the production efficiency of the product is improved, and meanwhile, the fermentation period is shortened.

The invention belongs to the technical field of medicines, and particularly relates to application of agastache rugosus stomach-soothing powder in hangover alleviating and preparation of products for preventing and / or treating liver-stomach injury caused by alcohol. The wrinkled gianthyssop herb stomach-soothing powder has a remarkable protection effect on alcohol-induced acute drunkenness and related liver and stomach injuries, and the protection effect is related to ethanol metabolism enhancement, oxidation resistance improvement, lipid peroxidation reduction and inflammatory reaction inhibition of the wrinkled gianthyssop herb stomach-soothing powder. The composition of the agastache rugosus stomach-soothing powder has relatively high dosage efficiency and synergistic effect, plays a role in multiple aspects, and provides more comprehensive protection.

The present invention relates to the use of fermented lactobacillus grx08 in the preparation of food, functional food and medicine with the effect of alleviating alcoholic liver damage and related symptoms thereof, and the preservation number of the fermented lactobacillus grx08 is CGMCC No: 7695. The fermented lactobacillus grx08 has the effect of reducing alcohol dehydrogenase and alleviating and restoring the balance of ethanol metabolism. The fermented lactobacillus grx08 has the effect of reducing alanine aminotransferase, reducing liver lipid accumulation, reducing liver lipid peroxidation products, and alleviating liver damage. Animal experiments have shown that fermented lactobacillus grx08 (CGMCC No: 7695) can restore the metabolic balance of rat alcohol dehydrogenase, reduce the level of alanine aminotransferase, reduce lipid accumulation and lipid peroxides in the liver, and alleviate liver damage. In addition, fermented lactobacillus grx08 can also alleviate kidney damage, enhance the tight connectivity of rat intestines, reduce inflammatory factors in the body, and alleviate the increase in blood sugar caused by acute alcohol intervention.

The invention provides pentapeptide and application thereof in preparation of a medicine for preventing and / or treating alcoholic liver injury. The pentapeptide with the amino acid sequence shown as SEQ ID NO: 1 not only can remarkably remove DPPH free radicals and ABTS free radicals and play an anti-oxidation role, but also can activate ADH enzyme and ALDH enzyme and play a role in promoting ethanol metabolism, so that the alcoholic liver injury is effectively prevented and / or treated, and the pentapeptide is very suitable for preparing the medicine for preventing and / or treating the alcoholic liver injury.

The present invention provides a kombucha fortified lactic acid bacteria beverage and a preparation method thereof, and the kombucha fortified lactic acid bacteria beverage comprises the following raw materials by weight: 3%-6% of white granulated sugar, 0.4%-1.0% of dry tea leaves, 3%-7% of microorganisms, 0.1%-0.3% of a stabilizer, 0.1%-0.3% of citric acid, and the balance purified water. The kombucha beverage added with the lactic acid bacteria can generate more healthy organic acids, improves the flavor of the beverage, is softer in smell, reduces the irritant sour taste, and improves the probiotic efficacy of the beverage at the same time. In the fermentation process, the white granulated sugar is a main carbon source and energy, the kombucha utilizes a white granulated sugar metabolism principle that yeast hydrolyzes the white granulated sugar into glucose and fructose through invertase, ethanol is generated through glycolysis, and metabolites are used as substrates for producing organic acids through metabolism of acetic bacteria and lactic acid bacteria; and meanwhile, the yeast can synthesize volatile acidic esters and fruity aromatic compounds which are very important for developing the aroma of black tea, so that the flavor and quality of the kombucha beverage are improved.

The invention discloses a brain tissue ethanol metabolism rate evaluation method. The method comprises the following steps: converting the ethanol content of a brain tissue by using serum; and calculating the area (AUC) under the drug-time curve of the brain tissues of the mice in each experimental group, and grading the metabolic capability of the wine body after drinking. According to the present invention, the influence of the alcohol beverage on the ethanol metabolism rate is represented by the ethanol content change of the brain tissue, such that the accumulation degree of the ethanol in the brain can be visually evaluated, the data reference is provided for the research of the relationship between the ethanol concentration and the after-drinking comfort level of the body, and the use of the experimental animal can be reduced through the method;

The invention provides an application of an active peptide in preparation of a product for preventing and treating ALD (Atomic Lymphosis Disease). The amino acid sequence of the active peptide is as shown in SEQ ID NO: 1, and the active peptide can activate ADH enzyme and ALDH enzyme to play a role in promoting ethanol metabolism, can also remarkably remove DPPH free radicals and ABTS free radicals to play an anti-oxidation role so as to effectively prevent and / or treat ALD, and is very suitable for preparing products for preventing and treating ALD.

The invention discloses application of elaeagnus angustifolia polysaccharide in preparation of a product for preventing and / or treating alcoholic liver injury, and belongs to the technical field of polysaccharide. The invention provides an application of elaeagnus angustifolia polysaccharide in preparation of a product for preventing and / or treating alcoholic liver injury, which verifies the prevention / treatment effect of the elaeagnus angustifolia polysaccharide on the alcoholic liver injury by adopting a mouse alcoholic liver injury model through pathological histological observation, liver function indexes, oxidative stress indexes, inflammatory factors and ethanol metabolism related enzymes. Results show that the elaeagnus angustifolia polysaccharide can improve the level of enzymes related to alcohol metabolism, improve redox imbalance caused by alcoholic liver injury, enhance the antioxidant ability of a body and relieve inflammatory injury of liver tissues by regulating and controlling an NF-kappa B pathway and regulating oxidative stress related indexes, inhibit overexpression of inflammatory factors, improve the level of enzymes related to alcohol metabolism, and can be used for preventing and treating liver injury. Therefore, the toxic effect of alcohol on the liver is remarkably reduced, and the effect of preventing and / or treating the alcoholic liver injury is achieved.

The invention provides cordyceps militaris corn peptide fermentation liquor as well as a preparation method and application thereof, and belongs to the technical field of corn peptide deep processing. The preparation method of the cordyceps militaris corn peptide fermentation liquor comprises the following steps: firstly, performing enzymolysis on a corn peptide powder solution by adopting alpha-amylase, and then adding saccharifying enzyme for performing enzymolysis to obtain enzymatic hydrolysate; glucose is added into the enzymatic hydrolysate, the pH is adjusted to be 5-7, then cordyceps militaris C.LSG-1 is added for fermentation, and cordyceps militaris corn peptide fermentation liquor is obtained. The corn peptide is subjected to enzymolysis treatment, so that the utilization efficiency of the raw materials in a fermentation system is improved, and subsequent cordyceps militaris fermentation can be smoothly carried out; cordyceps militaris is utilized to ferment corn peptide, so that the flavor is improved, and the functional characteristics of the corn peptide can be enhanced and improved. An in-vivo model verifies that the cordyceps militaris corn peptide fermentation liquor prepared by the preparation method disclosed by the invention has better functions of promoting ethanol metabolism and preventing and treating alcoholic liver injury.

The invention discloses a traditional Chinese medicine composition for promoting awakening, protecting brain and dispelling effects of alcohol for acute alcoholism and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from radix puerariae, hyacinth bean flowers, ginseng leaves, fructus amomi, hovenia dulcis thunb and fructus gardeniae. The preparation method of the traditional Chinese medicine composition comprises the following steps: S1, crushing fructus amomi, adding water for soaking, extracting volatile oil by using a steam distillation method, and collecting the volatile oil; s2, mixing hyacinth bean flowers and ginseng leaves, crushing, extracting, filtering and concentrating to obtain an extract A; s3, crushing kudzuvine root, hovenia dulcis thunb and cape jasmine, performing heating reflux extraction and filtration, combining filtrate with an aqueous solution obtained after volatile oil extraction in the step S1, and performing vacuum concentration to obtain an extract B; and S4, mixing the fructus amomi volatile oil, the extract A and the extract B, then adding sodium benzoate and vanillyl alcohol for corrosion prevention and taste modification, and performing sterilization and subpackaging. The traditional Chinese medicine composition disclosed by the invention has the effects of improving the level of ethanol metabolic enzyme in the brain, accelerating ethanol metabolism and reducing the level of central nervous monoamine neurotransmitter so as to play a role in promoting awakening, protecting the brain and dispelling the effects of alcohol.

The present invention discloses an alcohol decomposition enzyme protein capable of decomposing ethanol and acetaldehyde and its application. The alcohol decomposition enzyme protein comprises at least one protein region for decomposing ethanol and at least one protein region for decomposing acetaldehyde, wherein one protein region for decomposing ethanol is derived from human ethanol dehydrogenase, and the amino acid sequence is shown in SEQ ID NO: 1; and / or one protein region for decomposing acetaldehyde is derived from human acetaldehyde dehydrogenase, and the amino acid sequence is shown in SEQ ID NO: 2 or 3; or further comprises two protein tags, one protein tag Strep II, and the amino acid sequence is shown in SEQ ID NO: 4; and one protein tag HIS6, and the amino acid sequence is shown in SEQ ID NO: 5. The present invention obtains an alcohol decomposition enzyme protein by modern molecular biology methods, which can decompose ethanol and acetaldehyde, accelerate ethanol metabolism, and provide a new option for reducing the harm of drinking to the human body and protecting human health.

The invention discloses a freeze-drying reagent for human body ethanol metabolism gene detection and preparation and detection methods, the reagent is obtained by freeze-drying a reaction system, and the reaction system is a q-PCR detection reaction tube containing a reagent A and a reagent B. Compared with the existing liquid reagent, the freeze-drying reagent provided by the invention has the characteristics of supporting normal-temperature storage, being convenient to transport, being capable of getting rid of the problem of liquid cold chain transportation, being stored for more than 2 years, and having the positive effects of being not limited by a detection environment, getting rid of the problem of dependence on laboratory conditions, and being free from operation and interpretation of professionals; the method is convenient for non-professionals to operate, the detection result is not influenced, and the use requirement of the freeze-drying reagent is met, so that the use scene of the freeze-drying reagent can be expanded, and the method has great market competitiveness.

The present invention discloses the use of a plant polysaccharide in the preparation of a product for hangover relief and liver protection. The present invention proposes for the first time that frangipani polysaccharide can be effectively used for hangover relief and liver protection, including enhancing the activity of ADH and ALDH, key enzymes in the ethanol metabolic pathway, accelerating the rate of ethanol metabolism in the body, and reducing liver damage caused by drunkenness, having a protective effect on the body. At the same time, it can reduce the drunkenness rate, shorten the drunkenness time, significantly reduce the body's ALT, AST, TC, TG and LDL-C levels, increase the HDL-C level, significantly increase the body's liver CAT, SOD, and GSH activities, reduce the liver's MDA level, and significantly improve the body's liver fat accumulation, providing a new direction for the preparation of hangover relief and liver protection products.