The invention discloses semen cassia and radix puerariae anti-inebriation tea and a preparation method thereof. The semen cassia and radix puerariae anti-inebriation tea comprises the following raw materials in parts by weight: 70-80 parts of semen cassia, 60-70 parts of radix puerariae, 40-50 parts of honeysuckle, 30-40 parts of mulberry leaves, 30-40 parts of tangerine peel, 30-40 parts of granulated sugar, 4-5 parts of cicada pupa powder, 6-7 parts of tomatoes, 8-9 parts of codfish, 5-6 parts of freeze-dried kelp powder, 10-12 parts of white onion juice, 10-12 parts of rice soup, 4-5 parts of preserved plum, 3-4 parts of salted cucumbers, 5-6 parts of deep-fried tofu, 2-3 parts of wheat germ oil, 4-5 parts of water bamboo, 0.5-1 part of cordyceps sinensis, 0.5-1 part of safflower seeds, 1-2 parts of plantain, 1-2 parts of bamboo shavings, 1-2 parts of cucumber leaves, an appropriate amount of water and 40-50 parts of nutritional additives. The anti-inebriation tea has unique technology, delicious taste and rich nutrients, and the added traditional Chinese medicine has the efficiencies of regulating immune system function, suppressing tumor, preventing fatigue, invigorating lung and kidney, stop bleeding, reducing phlegm, promoting the production of body fluid, supplementing qi, whitening skin and removing black.