Pinctadafucata glycosaminoglycan containing effervescent tablet and preparation method thereof
A technology of Hepu Pinctada glycosamine and Pinctada glucosamine, applied in the field of Hepu Pinctada glycosaminoglycan effervescent tablets and its preparation, which can solve the problem of low utilization rate of high-value Hepu Pinctada shellfish problem, to achieve the effect of promoting sustainable and healthy development, mild effect, and no toxic side effects
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Embodiment 1
[0050] An effervescent tablet of Hepu Pinctada glycosaminoglycan that helps maintain normal immune function, the weight of the effervescent tablet is 202.3mg±2.8mg, containing 25% of Hepu Pinctada glycosaminoglycan and a disintegrant 36%, binder 2.5%, lubricant 2%, flavoring agent 3%, and the balance is lactose.
[0051] In the present embodiment, the preparation method of Hepu pearl oyster glycosaminoglycan effervescent tablet comprises the following steps:
[0052] (1) Take 2568g of Hepu pearl oyster meat tissue, after homogenization, add water to extract with a material-liquid ratio of 1:2, put it in a constant temperature water bath at 50°C for 5 hours under the action of a magnetic stirrer, and adjust the solution with 0.1mol / L sodium hydroxide pH to 7.6; add 15 mg of neutral protease and trypsin to hydrolyze per gram of Hepu pearl oyster shell meat (the mass ratio of neutral protease to trypsin is 7:8), and put it in a 50°C water bath for 4 hours under the action of a ma...
Embodiment 2
[0060] An effervescent tablet of Hepu Pinctada glycosaminoglycan that helps maintain normal immune function, the weight of the effervescent tablet is 198.6mg±2.4mg, containing 20% of Hepu Pinctada glycosaminoglycan and a disintegrant 33%, binder 2%, lubricant 2%, flavoring agent 3%, and the balance is lactose.
[0061] In the present embodiment, the preparation method of Hepu pearl oyster glycosaminoglycan effervescent tablet comprises the following steps:
[0062] (1) Take 2714g of Hepu pearl oyster meat tissue, after homogenization, extract with water at a material-liquid ratio of 1:2, place in a constant temperature water bath at 55°C for 4 hours under the action of a magnetic stirrer, and adjust the solution with 0.1mol / L sodium hydroxide pH to 7.2; add 12 mg of neutral protease and trypsin per gram of Hepu pearl oyster shell meat for hydrolysis (the mass ratio of neutral protease and trypsin is 7:8), and put it in a water bath at 55°C for 4 hours under the action of a m...
Embodiment 3
[0070] An effervescent tablet of Hepu Pinctada glycosaminoglycan that helps maintain normal immune function. The effervescent tablet weighs 205.1mg±4.0mg and contains 20% of Hepu Pinctada glycosaminoglycan and a disintegrant. 39%, binder 3%, lubricant 3%, flavoring agent 4%, and the balance is lactose.
[0071] In the present embodiment, the preparation method of Hepu pearl oyster glycosaminoglycan effervescent tablet comprises the following steps:
[0072] (1) Take 2618g of Hepu pearl oyster meat tissue, after homogenization, add water to extract with a material-liquid ratio of 1:2, put it in a constant temperature water bath at 50°C for 6 hours under the action of a magnetic stirrer, and adjust the solution with 0.1mol / L sodium hydroxide pH to 7.4; add 10 mg of neutral protease and trypsin to each gram of Hepu pearl oyster for hydrolysis (the mass ratio of neutral protease to trypsin is 7:8), and put it in a water bath at 50°C for 4 hours under the action of a magnetic stirr...
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