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A kind of preparation device and preparation method of dha algae oil nano liposome

A technology for preparing nano-liposomes and devices, applied in liposome delivery, chemical instruments and methods, food ingredients containing gas, etc., can solve problems such as complex exhaust process, device pressure imbalance, and affecting work process Good storage stability, reduced oxidation, and protection from oxidation

Active Publication Date: 2021-06-22
上海丰晟健康科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the traditional micro-fluidic devices are single-channel, and air bubbles must be strictly prevented from entering during use, otherwise the internal pressure of the device will be out of balance, affecting the normal working process. Once the instrument enters the air bubbles, the exhaust process will be quite complicated

Method used

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  • A kind of preparation device and preparation method of dha algae oil nano liposome
  • A kind of preparation device and preparation method of dha algae oil nano liposome
  • A kind of preparation device and preparation method of dha algae oil nano liposome

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preparation example Construction

[0022] A kind of preparation method of DHA algal oil nano liposome, concrete steps are as follows:

[0023] In the first step, mix 100kg soybean lecithin and 50-55kg DHA algae oil, stir until completely dissolved, and obtain phospholipid phase feed liquid; dissolve 10-12kg sodium caseinate in 5000-5200L drinking water, stir at medium temperature until completely dissolved , to obtain the aqueous phase feed solution;

[0024] In the second step, the carbon dioxide is introduced into the jet reaction chamber through the inlet channels 2 and 21, and the inlet valves 3 and 31 can control the inlet pressure and speed; at the same time, the phospholipid phase material liquid is introduced into the gas-assisted jet reaction chamber by using a high pressure of 80-90Mpa In the feed splitting area 1, a high pressure of 80-90Mpa is used to introduce the aqueous phase feed liquid into the feed splitting area 9; driven by the high pressure, the gas and the liquid pass through the microporo...

Embodiment 1

[0026]1. Weigh 100kg of soybean lecithin and 50kg of DHA algae oil, heat and stir until completely dissolved to obtain the phospholipid phase feed solution. Measure 5000L of drinking water, add 10kg of sodium caseinate, stir and heat until completely dissolved to obtain an aqueous phase feed solution. 2. Introduce carbon dioxide into the jet reaction chamber through the intake channels 2 and 21, and the intake valves 3 and 31 can control the intake pressure and speed; at the same time, the phospholipid phase feed liquid is introduced into the feed diversion area of ​​the gas-assisted jet reaction chamber with a high pressure of 80Mpa 1. Use 80Mpa high pressure to introduce the aqueous phase feed liquid into the feed splitting area 9 to obtain DHA algae oil nano-liposomes, and detect the physical and chemical properties.

Embodiment 2

[0028] 1. Weigh 100kg of soybean lecithin and 50kg of DHA algae oil, heat and stir until completely dissolved to obtain the phospholipid phase feed liquid. Measure 5000L of drinking water, add 10kg of sodium caseinate, stir and heat until completely dissolved to obtain an aqueous phase feed solution. 2. Use 80Mpa high pressure to introduce the phospholipid phase feed liquid into the feed split area 1 of the gas-assisted jet reaction chamber, and use 80Mpa high pressure to introduce the water phase feed liquid into the feed split area 9 to prepare DHA algae oil nano liposomes and detect the physical and chemical properties .

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Abstract

The invention relates to a preparation device and a preparation method of DHA algae oil nano-liposome. The gas-assisted jet flow reaction chamber includes a feeding pipeline, a gas pipeline, a hard material, a diversion pipeline, a fluid collision chamber, and a collision chamber. Chamber, diffuser tube. The gas-assisted jet reaction device provided by the invention can prepare DHA algae oil nano-liposomes in combination with the melting method, which greatly shortens the preparation time of nano-liposomes, does not introduce organic reagents, and can realize continuous production of liposomes, and the product It is stable in nature and can be used as a food-grade DHA supplement.

Description

Technical field: [0001] The invention relates to a preparation device and a preparation method of DHA algae oil nano-liposome, which belong to the fields of food processing, medicine and chemical industry. Background technique: [0002] Algae oil is directly extracted from artificially cultivated marine single-cell algae. It is mostly a light yellow liquid with a slight fishy smell at room temperature. It has not been passed through the food chain and does not interfere with the marine environment at all. It does not contain any pigments and is safe and pollution-free. . Algae oil is rich in polyunsaturated fatty acids. Algae oil is rich in omega-3 polyunsaturated fatty acids, mainly including docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA). DHA and EPA are important fatty acid components in brain, nerve and visual cells. These two unsaturated fatty acids are not only important components of higher animal cells, but also have functions such as anti-inflammation...

Claims

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Application Information

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IPC IPC(8): A61K31/202A61K9/127A61P29/00A61P35/00A61P3/06A61P3/08A61P37/04A61P9/00A23L33/115A23L29/00B01F15/02B01F5/06
CPCA61P3/06A61P3/08A61P9/00A61P29/00A61P35/00A61P37/04A23L29/015A23L33/115A61K9/127A61K31/202A23V2002/00B01F25/41B01F35/716B01F35/712A61K2300/00A23V2200/30A23V2250/1868A23V2250/11
Inventor 刘伟邹立强付冬文
Owner 上海丰晟健康科技有限公司
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