Fermentation method for producing N-acetylneuraminic acid

A technology of acetylneuraminic acid and fermentation method, applied in the field of fermentation for producing N-acetylneuraminic acid, can solve problems such as low yield, limited application scope, high cost, etc., and achieve the effects of increasing yield and improving synthesis rate
CN109628512AActive Publication Date: 2019-04-16HEFEI INSTITUTES OF PHYSICAL SCIENCE - CHINESE ACAD OF SCI +1
2 Cites 4 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
HEFEI INSTITUTES OF PHYSICAL SCIENCE - CHINESE ACAD OF SCI
Publication Date
2019-04-16

Smart Images

  • Figure 1
    Figure 1
Patent Text Reader

Abstract

The invention discloses a fermentation method for producing N-acetylneuraminic acid and relates to the technical field of N-acetylneuraminic acid production. The fermentation method for producing N-acetylneuraminic acid comprises the steps of adding supplementary feed liquid to a fermentation culture medium inoculated with N-acetyl-neuraminic acid bacteria during fermentation, wherein the feed liquid contains glycerin and an additive, the additive is selected from one or more of N-acetylglucosamine and polyphosphoric acid substances. The fermentation method improves the synthesis rate of N-acetylneuraminic acid and meanwhile improves the yield of the N-acetylneuraminic acid by optimizing the composition or use amount of the feed liquid.
Need to check novelty before this filing date? Find Prior Art

Description

Technical field

[0001] The present invention relates to the technical field of N-acetylneuraminic acid production, in particular to a fermentation method for producing N-acetylneuraminic acid. Background technique

[0002] N-acetyl neuraminic acid (N-acetyl neuraminic acid, NeuAc) is an acidic amino sugar with 9 carbon atoms and a pyranose structure. It is one of the main members of the sialic acid family. NeuAc is widely distributed in mammals and is an important part of cell membrane proteins. It participates in various physiological functions of the body: 1) anti-recognition effect; 2) improving infants’ intelligence and memory; 3) inhibiting leukocyte adhesion and anti-inflammatory; 4) anti-tumor , Anti-virus; 5) Anti-Alzheimer's, etc. NeuAc is widely used in the field of food, health products, cosmetics, pharmaceutical precursors and disease diagnosis, etc., and has significant market value.

[0003] At present, the main production methods of N-acetylneuraminic acid include:...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More