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Clove compound type natural preservative, preparation method and application in cosmetics

A technology of natural preservatives and cosmetics, applied in cosmetics, cosmetic preparations, cosmetic preparations, etc., can solve the problems of human injury, high irritation of chemically synthesized preservatives, and high skin sensitization rate, reducing irritation, The effect of inhibiting the reproduction of microorganisms and the simple process

Active Publication Date: 2019-04-26
EAST CHINA UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The safety of preservatives is one of the main considerations for the safety of cosmetics, while chemically synthesized preservatives are slightly more irritating and have a high sensitization rate to the skin, and long-term use will cause harm to the human body

Method used

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  • Clove compound type natural preservative, preparation method and application in cosmetics
  • Clove compound type natural preservative, preparation method and application in cosmetics
  • Clove compound type natural preservative, preparation method and application in cosmetics

Examples

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preparation example Construction

[0032] The preparation method of the clove ethyl acetate extract: the clove raw material is dried at 45° C., crushed and passed through a 50-mesh sieve, and set aside. Weigh 10g of clove powder, add the extraction agent ethyl acetate according to the ratio of solid to liquid at 1:10g / ml, soak for 12h, then ultrasonicate at 100Hz and 60°C for 30min, then reflux in a water bath to extract, the temperature is 60°C, and the time is 4h. Filtrate while hot, add the extractant ethyl acetate according to the ratio of material to liquid at 1:8g / ml for the second extraction, ultrasonicate at 100Hz, 60°C for 30min, filter and combine the filtrates, and concentrate by distillation under reduced pressure. The concentrated solution was extracted 3 times with 5% sodium hydroxide solution, and the obtained lye layer was adjusted to pH 3.5 with 1:1 aqueous hydrochloric acid solution, then extracted 3 times with ethyl acetate, and finally the ethyl acetate in the organic phase was removed to obt...

Embodiment 1

[0035] A clove compound type natural preservative is made from the following components in mass percentage:

[0036] Clove ethyl acetate extract 12.5%,

[0037] Clove n-Hexane Extract 12.5%,

[0038] 1,2-Propanediol 75%,

[0039] A preparation method of clove compound type natural antiseptic, comprises the following steps:

[0040] Add 1.25g of clove ethyl acetate extract and 1.25g of clove n-hexane extract to 7.5g of 1,2-propanediol, and 100Hz ultrasonic for 2min until completely mixed to obtain a clove compound natural preservative, which is ready for use.

Embodiment 2

[0042] A clove compound type natural preservative is made from the following components in mass percentage:

[0043] Clove ethyl acetate extract 8.3%,

[0044] Clove n-Hexane Extract 16.7%,

[0045] 1,2-Propanediol 75%,

[0046] A preparation method of clove compound type natural antiseptic, comprises the following steps:

[0047] Add 0.83g of clove ethyl acetate extract and 16.7g of clove n-hexane extract to 7.5g of 1,2-propanediol, and 100Hz ultrasonic for 2min until completely mixed to obtain a clove compound natural preservative, which is ready for use.

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Abstract

The invention discloses a clove compound type natural preservative which is prepared from the following components by weight percent: 5-25% of clove ethyl acetate extract, 10-25% of clove hexane extract and 50-75% of solvent. The invention also discloses an application of the clove compound type natural preservative in cosmetics. The clove compound type natural preservative provided by the invention has broad-spectrum sterilizing, anti-bacterial and preservative effects, is high in stability and can be widely applied to cosmetics.

Description

technical field [0001] The invention belongs to the technical field of natural preservatives, and relates to a cosmetic additive, in particular to a clove compound natural preservative, its preparation method and its application in cosmetics. Background technique [0002] In the past 40 years, the cosmetics industry in various countries in the world has developed rapidly, and people are increasingly pursuing the multifunctionality and safety of cosmetics. The multifunctionality of cosmetics requires it to contain rich nutrients, which just provide a good material basis for the growth and reproduction of microorganisms. The safety of preservatives is one of the main considerations for the safety of cosmetics, while chemically synthesized preservatives are slightly more irritating, have a high rate of skin sensitization, and can cause harm to the human body if used for a long time. Therefore, safe and highly effective antibacterial active substances that are natural, non-toxi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61Q19/00
CPCA61K2800/10A61K2800/524A61K2800/5922A61Q19/00A61K8/9789
Inventor 张文清夏玮徐志珍娄书琴张鹏吴梦琪陈林枭
Owner EAST CHINA UNIV OF SCI & TECH