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A kind of traditional Chinese medicine mouthwash and its preparation method and application

A technology of mouthwash and traditional Chinese medicine, which is applied in the field of preparation of oral health preparations, can solve the problems of not suitable for oral care of patients, low acceptance, turbid color, etc., and achieve the effects of slightly sweet taste, less infection, and easy preparation method

Active Publication Date: 2022-03-25
ZHEJIANG PROVINCIAL HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are traditional Chinese medicine mouthwashes on the market, but they generally have problems such as cloudy color, poor taste, or alcohol content, which makes them less acceptable and not suitable for oral care of postoperative patients.

Method used

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  • A kind of traditional Chinese medicine mouthwash and its preparation method and application
  • A kind of traditional Chinese medicine mouthwash and its preparation method and application
  • A kind of traditional Chinese medicine mouthwash and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment 1, prepare 100g Chinese medicine mouthwash

[0021] 1. Recipe

[0022]

[0023] Vitamin B complex is a compound preparation (commercially available), containing vitamin B1, vitamin B2, vitamin B6, niacinamide, and calcium pantothenate.

[0024] The sweetener is xylitol, the preservative is sorbic acid, and the active ingredient stabilizer is Tween 20.

[0025] 2, a preparation method of Chinese medicine mouthwash, the steps are as follows:

[0026] (1) Preparation of each selected single-flavor traditional Chinese medicine extract: place the selected traditional Chinese medicines (mint leaves, Radix Radix, Salvia miltiorrhiza, Scutellaria baicalensis) in a container, add 3 times the weight of water, soak at 4°C for 4h; boil again 1h, let stand, filter, and take the filtrate to obtain the extract of each single Chinese medicine;

[0027] (2) Mix the traditional Chinese medicine extract obtained in (1) according to the formula amount, add the ultrapure wa...

Embodiment 2

[0028] Embodiment 2, prepare 100g Chinese medicine mouthwash

[0029] 1. Recipe

[0030]

[0031] The vitamin B complex is a compound preparation (commercially available), containing vitamin B1, vitamin B2, vitamin B6, niacinamide, and calcium pantothenate.

[0032] The sweetener is aspartame (C 14 H 18 N 2 O 5 , Mr=294.30), the preservative is sodium benzoate, and the active ingredient stabilizer is Tween 20.

[0033] 2. The preparation method of a traditional Chinese medicine mouthwash is the same as in Example 1.

Embodiment 3

[0034] Embodiment 3. Determination of the antibacterial effect of mouthwash

[0035] (1) Preparation of agar plates

[0036] The mouthwashes prepared in Example 1 and Example 2 were added to the agar medium that was melted and cooled to about 60°C according to the volume ratio of 3:7, and the same amount of sterilized water was used as a negative control under the same conditions. The composition of agar medium: tryptone 1.0g, yeast extract 0.5g, sodium chloride 1.0g, agar 1.5g, dilute to 100mL with deionized water, sterilize under high pressure for 20 minutes, pour the plate to become an agar plate.

[0037] (2) Inoculate bacteria

[0038] E. coli (ATC8099) was grown to OD at 37°C, 180rpm 600 =0.6-0.8, obtain Escherichia coli bacterial liquid. After the agar plate prepared in step (1) was completely condensed, 0.05 mL of Escherichia coli bacterial liquid was taken and evenly spread on the above plate, and cultured at 37°C overnight.

[0039] The results showed that a larg...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine mouthwash and its preparation method and application. The traditional Chinese medicine mouthwash is made of the following raw materials in the weight ratio: mint leaf extract 0.1-0.3%, Patrinia extract 0.2-0.4%, Salvia miltiorrhiza extract 0.1‑0.2%, Scutellaria baicalensis extract 0.02‑0.05%, vitamin B complex 0.01‑0.02%, sweetener 1‑3%, preservative 0.1‑0.2%, active ingredient stabilizer 0.01‑0.02%, balance It is ultrapure water; the traditional Chinese medicine mouthwash of the present invention can be used for oral care of postoperative patients, reducing the chance of infection caused by oral ulcers in postoperative patients and improving the success rate of rehabilitation. The invention has simple materials, easy-to-operate preparation method, low cost, strong pertinence, aromatic taste and slightly sweet taste, and is a beneficial supplement to oral care products.

Description

(1) Technical field [0001] The invention belongs to the technical field of preparation of oral health care preparations, in particular to a traditional Chinese medicine mouthwash and a preparation method thereof. (2) Background technology [0002] In China, oral health is receiving unprecedented attention. With the development of the economy and the improvement of living standards, people's awareness of oral health care has also been greatly enhanced. With the improvement and change of market demand and consumption concept, the pattern of oral care products has gradually upgraded from the initial domination of toothpaste to a group of products such as toothpaste, dental floss, tooth paste, mouthwash, and electric toothbrush. At present, dental caries is one of the most common diseases of the oral cavity. The average caries rate is about 50%. It is the main common disease of the oral cavity and one of the most common diseases of human beings. Three key diseases for human be...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K8/67A61Q11/00A61P1/02
Inventor 叶宝东沈一平林婉冰俞青宏高燕婷张圆圆于芬芬陈甜
Owner ZHEJIANG PROVINCIAL HOSPITAL OF TRADITIONAL CHINESE MEDICINE