Traditional Chinese medicine ultrasonic targeted drug-delivery coupling paster for treating rheumatic ostealgia and preparation process thereof
A technology for targeted drug delivery and rheumatic bone pain, which is applied in drug combinations, medical preparations containing active ingredients, etc. To solve the problem, achieve scientific and reasonable extraction process, reduce the interference of impurities, and achieve the effect of high effective concentration
Inactive Publication Date: 2019-07-02
辽宁蓝色海豚医疗科技有限公司
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Problems solved by technology
In 2009, it was officially listed as a national medical insurance fee; now there is also a method of ultrasonic transdermal targeted drug delivery to treat patients with rheumatic bone pain, but its treatment effect is poor, and the cost is high, and the production steps are cumbersome, which is not conducive to effective promotion
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[0026] Reflux extraction of active ingredients: grind 30-90g Panax notoginseng, 4-17g velvet antler and 7-54g cinnamon into coarse powder, mix with 30-100g safflower, 25-80g fennel and 20-85g schisandra, and add 6-12 times the total weight of 70% ethanol solution, soak for 50min-2.5h, reflux extraction at 50-100℃ for 40min-2.5h, filter; then add 6-12 times the amount of 70% ethanol solution, continue to reflux and extract for 30min to 2h, combine the filtrates and weigh them for later use, and separate the filter residue for later use;
[0027]Extract active ingredients by decocting: 70-185g Angelica, 15-90g Chuanxiong, 60-140g Drynaria, 30-95g Epimedium, 55-160g Cnidium, 70-140g Dipsacus, 25-95g Eucommia, 80- 170g aconite, 85-170g Caulis Spatholobus, 40-105g licorice, 60-130g Angelica dahurica, 55-130g psoralen, 45-130g Achyranthes bidentata, 30-100g Cistanche deserticola, 120-210g honeysuckle vine, 50-130g Qingfeng vine , 40-100g of solitary, 30-100g of notopterygium, 20-90...
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The invention relates to the technical field of treating rheumatic ostealgia, in particular to a traditional Chinese medicine ultrasonic targeted drug-delivery coupling paster for treating rheumatic ostalgia and a preparation process thereof, the clinical application effect is good, the cost is low, the production is convenient, and the popularization is easy. The paster comprises the following ingredients: safflower, pseudo-ginseng, pilose antler, cinnamon, common fennel fruit, Chinese magnoliavine, achyranthes root, Chinese angelica, Ligusticum wallichii, Rhizoma Drynariae, epimedium, commoncnidium fruit, Himalayan teasel root, eucommia, aconitum carmichaelii, spatholobus stem, licorice, dahurian angelica root, psoralea corylifolia, Cistanche, Lonicera japonica, orienavine, radix angelicae pubescentis, notopterygium root, Artemisia argyi, Radix Astragali and deer blood; The preparation process comprises the following steps: S1, reflux extraction of active ingredients; S2, decoctionextraction of active ingredients; S3, decompression concentration treatment; S4, deer blood treatment; and S5, mixing treatment. The paster has unique formula and scientific and reasonable extractionprocess, and the obtained paster has a good transdermal rate, so that the drug has a high effective concentration in the lesion, and more obvious clinical effects can be ensured.
Description
technical field [0001] The invention relates to the technical field of treating rheumatic ostalgia, in particular to a traditional Chinese medicine ultrasonic targeted drug delivery coupling patch for treating rheumatic ostealgia and a preparation process thereof. Background technique [0002] Rheumatic bone pain disease is caused by the invasion of the human body by wind, cold and dampness. After the wind, cold and dampness invades the human body, it will block the tendons and arteries. It is a general term for orthopedic pain-related diseases. It is a disease with pathological hyperplasia and deformation of bone, inflammation or joint wear leading to local joint, muscle and ligament movement disorders, accompanied by pain as the main symptom. Can occur in the cervical spine, lumbar spine, joints and calcaneus, including arthritis, synovitis, tenosynovitis, cervical spondylosis, lumbar spondylosis, etc. The disease is prone to occur in middle-aged and elderly people over 4...
Claims
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IPC IPC(8): A61K36/79A61K36/714A61K9/70A61K47/10A61K47/22A61K47/44A61P29/00A61P19/08A61P19/02A61P21/00A61P19/04A61K35/14A61K35/32
CPCA61K9/0004A61K9/0014A61K9/7023A61K35/14A61K35/32A61K36/126A61K36/185A61K36/21A61K36/232A61K36/234A61K36/235A61K36/236A61K36/237A61K36/258A61K36/282A61K36/286A61K36/296A61K36/355A61K36/46A61K36/481A61K36/484A61K36/486A61K36/487A61K36/54A61K36/57A61K36/59A61K36/64A61K36/714A61K36/79A61K47/10A61K47/22A61K47/44A61K2236/333A61K2236/39A61P19/02A61P19/04A61P19/08A61P21/00A61P29/00A61K2300/00
Inventor 朴永南
Owner 辽宁蓝色海豚医疗科技有限公司