Preparation technology and application of weight-reducing hypolipidemic microbial agent and derivative thereof

A technology of compound microbial inoculants and microbial flora, applied in the fields of medicine and health, personalization of health products or medicines, and natural micro-ecological health food, can solve the problems of inability to meet the needs of micro-ecological products, large side effects, and general curative effect, etc. The effect of inhibiting reproduction and the formation of corrupt substances, promoting proliferation, and protecting original functions

Inactive Publication Date: 2019-07-09
银川尧玥生物科技有限公司 +1
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  • Abstract
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Problems solved by technology

[0003] However, most of the hypolipidemic drugs currently on the market are chemically synthesized drugs, with general curative effects and large side effects.
There are also some single strains or blind (for different individuals, the proportion of the flora remains unchanged) compound strains for fermentation, and the ingredients are relatively fixed, which cannot meet the microecological products of different races and individuals

Method used

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  • Preparation technology and application of weight-reducing hypolipidemic microbial agent and derivative thereof
  • Preparation technology and application of weight-reducing hypolipidemic microbial agent and derivative thereof
  • Preparation technology and application of weight-reducing hypolipidemic microbial agent and derivative thereof

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[0036] Implementation case (animal experiment)

[0037] Internationally, a large number of experiments have verified that the method of using rats to conduct blood lipid regulation health food and / or drug function evaluation experiments is very mature and reliable. The standard method "Health Food Functional Evaluation Procedures and Test Methods" promulgated by the Ministry of my country has clearly stipulated that rats can be used as experimental materials for screening, precise detection and evaluation experiments of blood lipid-lowering health food and / or drug efficacy. Therefore, the present invention is designed to reduce blood fat and body weight. In order to customize the microbial agent that meets their individual needs, firstly, a normal rat microbial database was constructed, and the distribution ratio information of the microbial composition in the stool samples of the 30 Wistar male rats was obtained through high-throughput 16S rRNA gene sequencing (the process is...

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Abstract

The invention discloses a preparation method of an active compound microbial agent and a derivative microecological product thereof and application of healthcare food, healthcare products or drug having functions of lowering blood lipid and assisting in weight reduction in lowering blood lipid and preventing and treating related diseases like obesity and cardiovascular and cerebrovascular diseases. Active compound microbial strains are all from various natural strains of healthy people. According to a biological information analysis and management platform, an active compound microbial strainformula is optimized and improved to obtain the high-quality active compound microbial agent and a derivative thereof; harm caused by adding chemical reagents is avoided; the active compound microbialagent has efficacy of retaining diverse symbiotic flora functions of intestinal tract and regulating flora balance and fat metabolism; the problem of conventional unitary production processes is solved, a new path is provided fir high-value production of micro-ecological products, industrial blank is filled, and the active compound microbial agent has good application prospect; scientific conclusions closely related to diseases like gastrointestinal micro-ecological disorder and obesity and cardiovascular and cerebrovascular diseases are applied and improved.

Description

technical field [0001] The invention belongs to the technical field of personalized customization of natural micro-ecological health food, health care products or medicines, and more specifically relates to the formulation method and precise application of micro-ecological personalized formula for weight loss and blood fat reduction in the field of medicine and health. Background technique [0002] Human beings have entered the 21st century, and living standards have been significantly improved. Diseases related to lifestyles such as obesity and cardiovascular and cerebrovascular diseases seriously threaten human health. A large number of epidemiological surveys and studies have shown that hyperlipidemia is an important risk factor for these diseases. [0003] However, most of the hypolipidemic drugs currently on the market are chemically synthesized drugs, which have general curative effects and large side effects. There are also some single strains or blind (for different...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12N1/20A61K35/747A61K35/741A61K35/745A61K35/744A61P3/06A61P3/04A61P9/00A23L33/135C12R1/23C12R1/25C12R1/245C12R1/01C12R1/46
CPCC12N1/20A61K35/747A61K35/741A61K35/745A61K35/744A61P3/06A61P3/04A61P9/00A23L33/135A61K2236/19A61K2236/11A23V2002/00A23V2400/125A23V2400/113A23V2400/249A23V2400/51A23V2400/169A61K2300/00A23V2200/3262A23V2200/332A23V2200/326
Inventor 尹星胡建中
Owner 银川尧玥生物科技有限公司
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