Lactobacillus fermentum capable of reducing blood uric acid

A technology for fermenting lactobacillus and blood uric acid, applied in the field of microorganisms, can solve problems such as allergic reactions, side reactions, liver function damage, etc., and achieve the effects of inhibiting intake, lowering uric acid levels, and lowering blood uric acid levels

Active Publication Date: 2019-08-02
HANGZHOU WAHAHA TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, most drugs have side effects of varying degrees, such as severe allergic reactions, gastrointestinal reactions, bone marrow suppression, liver function damage, etc.

Method used

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  • Lactobacillus fermentum capable of reducing blood uric acid
  • Lactobacillus fermentum capable of reducing blood uric acid
  • Lactobacillus fermentum capable of reducing blood uric acid

Examples

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Embodiment 1

[0027] Example A strain of Lactobacillus fermentum that can reduce blood uric acid was obtained from traditional yogurt collected near Alashankou in Xinjiang Uygur Autonomous Region of China in the previous work of the inventor. It was identified as Lactobacillus fermentum and named as 2644 strain. It was preserved in the General Microorganism Culture Collection Center of China Microbiology Culture Collection Management Committee on November 19, 2018. The microorganism preservation number is CGMCC NO.16754. The biological properties of the strain are as follows:

[0028] Morphological characteristics: In MRS agar medium, the growth form is milky white colony, opaque, round, smooth and moist surface, neat edges, and raised in the center. Gram staining was typically positive, and under the microscope the cells were short rod-shaped, without flagella, non-spore-forming, and non-moving ( Figure 1-2 shown).

[0029] Culture characteristics: The optimum growth temperature is 37°C...

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Abstract

The invention relates to the field of microorganisms, and discloses lactobacillus fermentum capable of reducing blood uric acid. The strain is named 2644 strain, and is preserved at the China GeneralMicrobiological Culture Collection Center on 19th, November, 2018, and a microbial preservation number is CGMCC NO.16754; and the preservation authority address is NO.3 1# Courtyard, Beichen West Road, Chaoyang District, Beijing, and the microorganism is classified and named Lactobacillus fermentum. The strain can effectively reduce the content of the blood uric acid; and not only can intake of exogenous purines be reduced, but also discharge of internal uric acid from an intestinal tract can be promoted so that the blood uric acid level of a body can be more effectively controlled.

Description

technical field [0001] The invention relates to the field of microorganisms, in particular to a lactobacillus fermentum capable of reducing blood uric acid. Background technique [0002] Clinically, hyperuricemia can be diagnosed when the blood uric acid level of men is greater than 7.0 mg / dL and that of women is greater than 6.0 mg / dL. According to statistics, the prevalence of hyperuricemia in the general population in my country is about 10%, which is comparable to the prevalence of diabetes; while the prevalence of hyperuricemia in coastal and economically developed areas is above 20%. The 2017 China Gout Status Survey shows that the number of patients with hyperuricemia in my country has reached 170 million. Gout has become the second largest metabolic disease in my country after diabetes. [0003] The amount of uric acid in the circulating blood is mainly determined by the dynamic relationship between the synthesis and excretion of uric acid in the human body. The s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12N1/20A23L33/135A61K35/747A61P19/06C12R1/225
CPCA23L33/135A61K35/747A61P19/06A23V2002/00C12R2001/225C12N1/205A23V2400/143A23V2200/30
Inventor 朱珺孙盛李言郡陈作国陈苏任学良姜雄韬
Owner HANGZHOU WAHAHA TECH
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