Specific area boundary detection and positioning method and system for complex component sample

Abstract

The invention relates to a specific area boundary detection and positioning method and system for a complex component sample. The method particularly comprises steps: laser is shaped and emitted, andcolumnar laser shaped by a cylindrical lens is vertically irradiated to a sample horizontal placement plane; a galvomirror is adopted to change the position of the columnar laser irradiated to the horizontal placement plane of a to-be-detected sample, photoacoustic signals are acquired, a spectrum-sound power spectrum joint map of the to-be-detected sample at the position can be obtained through signal processing, and through the sound power spectrum amplitude after energy normalization on a differential spectrum-sound power spectrum joint map, the information such as the molecular chemistry and the microstructure of the to-be-detected sample at the position can be determined for further boundary detection and positioning. The system comprises a pulsed laser source, a slide glass, a needlehydrophone, an amplifier, an oscilloscope, the cylindrical lens, the galvomirror and a computer. In view of the problem that the current medical device can only perform boundary detection and positioning distinguishing from the physical point of view, a new boundary detection scheme is put forward, and the new boundary detection scheme has dual advantages of high sensitivity and deep penetrationdepth.

Description

technical field [0001] The invention relates to the technical field of medical equipment, in particular to a method and system for boundary detection and positioning of a specific area for complex component samples. Background technique [0002] One of the main reasons for the postoperative survival rate is that not all the tissue in a specific area was removed during the operation, resulting in residual positive margins. [0003] With the development of the times, how to achieve accurate and rapid identification of boundaries in specific regions during surgery has become a common goal in the medical field. At present, the existing new technologies for intraoperative auxiliary calibration of boundaries include: intraoperative ultrasound assistance, intraoperative CT, intraoperative In MRI, etc., the above technologies have their own advantages and disadvantages, and they are unable to distinguish tissues with similar physical properties but different chemical properties. A m...

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Problems solved by technology

[0004] The purpose of the present invention is to provide a specific area boundary detection and positioning method and system for complex component samples in order to overcome the above-mentioned defects in the prior art, aiming at the existing boundary detection and positioning technology can only be determined from a physical point Due to the limitation of the boundary detection and positioning of the specific area of ​​the sample, a method is proposed to analyze the tissue components from the chemical molecular level to determine the properties of the tissue, and compare the differences between different positions in the specific area of ​​​​the horizontal plane of the sample to be tested and the reference tissue through differential calculation. The difference spectrum-acoustic power spectrum joint map can distinguish the molecular chemistry, microstructure and other information of adjacent tissue regions, so as to achieve the purpose of boundary calibration

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