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Traditional Chinese medicine compound composition for treating chronic atrophic gastritis and gastric precancerous lesions and application thereof

A technology for atrophic gastritis and precancerous lesions of gastric cancer, which is used in drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients to reduce morbidity and mortality, improve cure rates, and reduce economic and psychological burdens. Effect

Active Publication Date: 2019-09-03
大连市中医医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is still a lack of suitable effective drugs and therapies to reverse or block the occurrence of this disease

Method used

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  • Traditional Chinese medicine compound composition for treating chronic atrophic gastritis and gastric precancerous lesions and application thereof
  • Traditional Chinese medicine compound composition for treating chronic atrophic gastritis and gastric precancerous lesions and application thereof
  • Traditional Chinese medicine compound composition for treating chronic atrophic gastritis and gastric precancerous lesions and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A traditional Chinese medicine composition for treating chronic atrophic gastritis and gastric precancerous lesions, which is made of the following raw materials in parts by weight: Codonopsis 15g, Stir-fried Atractylodes Rhizoma Atractylodes Rhizome 10g, Jiang Pinellia 10g, Scutellaria baicalensis 15g, Coptis chinensis 5g, Gallus chinensis 20g, sea octopus 20g, Muxiang 5g, Smilax smilax 30g, Paojiang 5g, Hedyotis diffusa 20g, Salvia miltiorrhiza 10g, Tangerine peel 15g, Magnolia officinalis 10g; Take the above raw materials, add 800mL of water, decoct for 1 hour, filter; filter residue Add 300mL of water, decoct and extract for 0.5 hours, filter; combine the filtrates from two times, and heat and concentrate the filtrate to a 200mL concentrate.

Embodiment 2

[0030]A traditional Chinese medicine composition for treating chronic atrophic gastritis and gastric precancerous lesions, which is made of the following raw materials in parts by weight: Codonopsis 12g, Stir-fried Atractylodes macrocephala 9g, Jiang Pinellia 9g, Scutellaria baicalensis 12g, Coptis chinensis 3g, Gallus gallus chinensis 12g, and squid octopus 18g servings, 3g Muxiang, 25g Smilax, 5g Paojiang, 15g Hedyotis diffusa, 6g Salvia, 10g Tangerine Peel, 6g Magnolia officinalis; take the above raw materials, add 700mL of water, decoct for 1 hour, filter; Add 200 mL of water to the filter residue, decoct and extract for 0.5 hour, and filter; combine the filtrates from two times, and heat and concentrate the filtrate to 200 mL of concentrate.

Embodiment 3

[0032] A traditional Chinese medicine composition for treating chronic atrophic gastritis and gastric precancerous lesions, which is made of the following raw materials in parts by weight: Codonopsis 18g, Stir-fried Atractylodes macrocephala 15g, Jiang Pinellia 15g, Scutellaria baicalensis 18g, Coptis chinensis 6g, Gallus chinensis 20g, Sea slug octopus 25g, Muxiang 10g, Smilax smilax 40g, Paojiang 9g, Hedyotis diffusa 25g, Salvia miltiorrhiza 15g, Tangerine peel 10g, Magnolia officinalis 15g; Take the above raw materials, add 950mL of water, decoct and extract for 1.5 hours, filter; Add 400mL of water, decoct and extract for 0.8 hours, and filter; combine the filtrates twice, and heat and concentrate the filtrate to a 200mL concentrate.

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Abstract

The invention belongs to the field of traditional Chinese medicine, and in particular, relates to a traditional Chinese medicine compound composition for treating chronic atrophic gastritis and gastric precancerous lesions and an application thereof. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: codonopsis pilosula, roasted rhizoma atractylodis macrocephalae, ginger processed pinellia, radix scutellariae, coptis chinensis, endothelium corneum gigeriae galli, cuttlebone, radix aucklandiae, rhizoma smilacis glabrae, baked ginger, oldenlandia diffusa, radix salviae miltiorrhizaea, pericarpium citri reticulatae and magnolia officinalis. The traditional Chinese medicine composition has the functions of invigorating qi, invigorating spleen, eliminating ruffian and eliminating stagnation, is suitable for syndromes of weak spleen and stomach, and stagnation of turbid phlegm poison, and can be used for treating chronic atrophic gastritis with intestinal metaplasia or dysplasia.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, in particular to a compound traditional Chinese medicine composition for treating chronic atrophic gastritis and gastric precancerous lesions and an application thereof. Background technique [0002] Gastric cancer is considered to be a malignant disease that threatens human health. It is also a very common malignant tumor in my country, and its mortality and morbidity rank first among digestive tract cancers in China. [1-2] . Gastric cancer is the gradual development from chronic atrophic gastritis to gastric precancerous lesions, and then to cancer [3] . Gastric carcinogenesis pattern Cornea pattern [4] Is: normal gastric mucosa - chronic superficial gastritis - chronic atrophic gastritis - intestinal metaplasia - dysplasia (moderate to severe) - gastric cancer (intestinal type). Precancerous lesions of gastric cancer (PLGC) are an important process in the process of gradual tra...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P1/04A61P35/00A61K35/57A61K35/618
CPCA61K35/57A61K35/618A61K36/284A61K36/285A61K36/344A61K36/537A61K36/539A61K36/575A61K36/718A61K36/748A61K36/752A61K36/8888A61K36/896A61K36/90A61K36/9068A61K2236/331A61K2236/39A61P1/04A61P35/00A61K2300/00
Inventor 李吉彦沈会
Owner 大连市中医医院
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