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Rosa chinensis extract, product containing rosa chinensis extract and preparation method and application of rosa chinensis extract

An extract and Chinese rose technology, which is applied in the field of Chinese rose extracts, can solve problems such as the Chinese rose extract that has not yet been seen, and achieves the effects of simple preparation method, convenient material collection and broad application prospect.

Pending Publication Date: 2019-09-06
SHANGHAI SHENG WEI BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But so far, there is no report that rose extracts can inhibit Malassezia

Method used

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  • Rosa chinensis extract, product containing rosa chinensis extract and preparation method and application of rosa chinensis extract
  • Rosa chinensis extract, product containing rosa chinensis extract and preparation method and application of rosa chinensis extract
  • Rosa chinensis extract, product containing rosa chinensis extract and preparation method and application of rosa chinensis extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] Preparation of rose extract

[0045] (1) Add 10 kg of 70% ethanol aqueous solution to 1 kg of Chinese rose, and extract by circulating percolation at 60° C. for 2 hours to obtain an extract;

[0046] (2) 100 mesh sieves filter the extract to obtain the filtrate, add 500 g of 1% chitosan solution (the solvent in the chitosan solution is 2% acetic acid aqueous solution), stir at 40° C. for 10 min, let stand for 30 min, and filter again until clarification;

[0047] (3) Pour the clarified liquid into D101 macroporous resin for adsorption, use 70% ethanol aqueous solution as the eluent to elute, and collect the eluate;

[0048] (4) Concentrating the eluate under reduced pressure, removing ethanol and water, and drying in a vacuum to obtain the rose extract.

Embodiment 2

[0050] Preparation of rose extract

[0051] Add 6 kg of 50% ethanol aqueous solution to 1 kg of Chinese rose, extract by circulatory percolation at 50° C. for 2 hours to obtain an extract; the rest of the steps are the same as in Example 1.

Embodiment 3

[0053] Preparation of rose extract

[0054] Add 15 kg of 90% ethanol aqueous solution to 1 kg of Chinese rose, extract by circulatory percolation at 70° C. for 2 hours to obtain an extract; the rest of the steps are the same as in Example 1.

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Abstract

The invention discloses a rosa chinensis extract, a product containing the rosa chinensis extract and a preparation method and application of the rosa chinensis extract. The preparation method of therosa chinensis extract includes steps: (1) extracting rosa chinensis extract liquid, wherein 50-90% ethanol aqueous solution serves as a solvent, a mass ratio of rosa chinensis to a solvent is 1: (6-15) and an extraction temperature is 50-70 DEG C; (2) filtering the extract liquid to obtain filtrate; (3) after macroporous resin adsorption of the filtrate, eluting to obtain eluent; (4) concentrating the eluent, and drying to obtain the rosa chinensis extract. Convenience in material acquisition is achieved, the preparation method is simple, and the rosa chinensis extract and the product containing the rosa chinensis extract can be used for treatment of skin diseases caused by malassezia and have a promising application prospect.

Description

technical field [0001] The invention relates to a rose extract, a product containing it, a preparation method and application thereof. Background technique [0002] Malassezia is a resident flora on the skin of humans and warm-blooded animals, belonging to the genus Lipophilic Basidiomycetes. As early as decades ago, three species of Malassezia had been found on the skin of warm-blooded animals: Malassezia furfur, Malassezia pachyderm, and Malassezia symphysis. Then in people's research, it was found that there are 7 kinds of Malassezia, that is, in addition to the above 3 kinds, there are Malassezia globosa, Malassezia obtuse, Malassezia restrictive and Malassezia slofi bacteria. Malassezia mainly grows in the stratum corneum of human beings. It is a lipophilic flora. It mainly uses triacylglycerol and free fatty acid on the skin surface as nutrition, and affects the secretion of triacylglycerol and free fatty acid less. reduce. Malassezia grows in yeast phase and hypha...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/738A61P17/00A61P17/08A61P17/06A61P31/10A61K8/9789A61Q5/00A61Q19/00
CPCA61K36/738A61K2236/333A61K2236/51A61K2236/55A61Q5/00A61Q19/00A61K8/9789A61P17/00A61P17/06A61P17/08A61P31/10
Inventor 翟春涛金敏蓉郑木创
Owner SHANGHAI SHENG WEI BIOTECHNOLOGY CO LTD