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Method for preparing artificial joint prosthesis by using 3D printing technology

An artificial joint and 3D printing technology, applied in 3D printing, prosthesis, manufacturing tools, etc., can solve the problems of prolonging operation time, poor shape fitting, aggravating local trauma, etc., and achieve mature preparation technology, weak stress shielding effect, Porosity controllable effect

Inactive Publication Date: 2019-09-10
SHANGHAI CHANGZHENG HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Moreover, the artificial prosthesis prepared by the traditional method has poor shape fit to the surgical site, and it is often necessary to repeatedly try various types of prostheses during the operation, which easily aggravates the local trauma and prolongs the operation time

Method used

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  • Method for preparing artificial joint prosthesis by using 3D printing technology
  • Method for preparing artificial joint prosthesis by using 3D printing technology
  • Method for preparing artificial joint prosthesis by using 3D printing technology

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1 Artificial joint prosthesis of the present invention

[0034] One, the structure of artificial joint prosthesis of the present invention

[0035] The artificial joint prosthesis with bionic function of the invention is composed of a porous layer, a compact layer and an embedded layer. Such as Figure 1-Figure 3 As shown, among them, figure 1 and figure 2 Indicates the positional relationship, proportional relationship between different layers and the internal structure of each layer, image 3 Indicates the shape of the artificial joint that is actually produced, and the size of the artificial joint can be adjusted according to the specific conditions of the patient.

[0036] 1. Porous layer

[0037] The porous layer is the contact part of the articular surface, designed as a porous structure, and the material used is nano-hydroxyapatite / polyamide 66. The porosity of the porous structure is 85% to 90%, the inner diameter of the pores is 200 to 350 μm,...

experiment example 1

[0050] Experimental Example 1: Different Pore Sizes of Porous Layers to Cultivate Chondrocyte Layers

[0051] The artificial joint prosthesis prepared by the method of the present invention is taken, inoculated with cells, and cultured.

[0052] Experimental results show that the specific porosity and inner diameter in the porous structure of the porous layer of the present invention are beneficial to the cultivation of the chondrocyte layer.

experiment example 2

[0053] Experimental Example 2 Application of Artificial Joint Prosthesis in Reconstruction of Large Segmental Bone Defect

[0054] The artificial joint prosthesis prepared by the method of the present invention is used for bone defect reconstruction.

[0055] The experimental results show that the cultivation of the chondrocyte layer on the porous structure of the present invention is beneficial to the realization of the motor function; the macroporous structure added to the dense layer is filled with autologous bone tissue, so that the artificial joint prosthesis and the surrounding bone tissue "grow" as one, which can realize Good bone tissue fusion, autologous bone tissue vascularization and better supporting function.

[0056] In summary, the present invention provides a method for preparing an artificial joint prosthesis using 3D printing technology. The present invention uses 3D printing technology to "tailor-made" the artificial joint prosthesis with bionic functions to...

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Abstract

The invention discloses a method for preparing an artificial joint prosthesis by using a 3D printing technology. The method includes the following steps: (1) a digital model of the artificial joint prosthesis is designed; and the artificial joint prosthesis comprises a porous layer, a compact layer and an embedding layer; (2) the digital model is introduced into a 3D printing device; and (3) according to the introduced digital model, a nano-hydroxyapatite / polyamide 66 powder material is fused layer by layer, and the artificial joint prosthesis is prepared by utilizing 3D printing. The artificial joint prosthesis with a special structure of the porous layer, the compact layer and the embedding layer "customized" by using the 3D printing technology is more accurate in matching with bones ofa patient, functional recovery of ill limbs is faster, and the operation time can be obviously shortened, complications of loosening and sinking of the prosthesis are reduced, and the service life ofan artificial joint is prolonged.

Description

technical field [0001] The invention relates to a method for preparing an artificial joint prosthesis by using 3D printing technology. Background technique [0002] With the development of the economy and the improvement of people's living standards, artificial joint replacement has been widely used clinically and has achieved good clinical results. It is recognized as an effective treatment method for various ultimate joint diseases. However, with the passage of time, complications such as prosthesis loosening and sinking caused by this operation have become increasingly prominent, seriously affecting the clinical efficacy of the operation and the quality of life of the patient. Once patients have these adverse outcomes, patients often need to undergo revision surgery, which not only increases the patient's surgical pain and medical expenses, but also the clinical efficacy after revision is far less ideal than the initial surgery. [0003] At present, artificial joint mate...

Claims

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Application Information

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IPC IPC(8): A61F2/30A61L27/38A61L27/46A61L27/50A61L27/56
CPCA61F2/30771A61F2/30942A61F2002/30772A61F2002/30985A61L27/3817A61L27/46A61L27/50A61L27/56A61L2430/24C08L77/06
Inventor 刘铁龙胡一为白广建高欣王静刘永刚陈广辉汪洋刘戈曹佳实刘伟波杨家祥董连峰信保全吕凯
Owner SHANGHAI CHANGZHENG HOSPITAL
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