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Traditional Chinese medicine composite, and preparation method and application thereof

A technology of composition and traditional Chinese medicine, which is applied in the direction of drug combination, medical formula, plant raw materials, etc., can solve the problems of dominance impact, etc., and achieve the effect of improving utilization, short time and high efficiency

Pending Publication Date: 2019-09-17
广东合威制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current situation of traditional Chinese medicine is not optimistic. Not only the traditional dominant position has been impacted in the competition with foreign natural medicines, but also the living space of traditional Chinese medicine in the domestic market has also been challenged.

Method used

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  • Traditional Chinese medicine composite, and preparation method and application thereof
  • Traditional Chinese medicine composite, and preparation method and application thereof
  • Traditional Chinese medicine composite, and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0089] The composition of raw materials (parts by weight) is the preparation of a pharmaceutical composition comprising 120 parts of Astragalus membranaceus, 110 parts of Rehmannia glutinosa, 110 parts of Rhizoma Polygonatum and 10 parts of leeches.

[0090] The Chinese medicine composition is prepared according to the following method:

[0091] S1. Treatment of medicinal materials: fresh astragalus, rehmannia root, sealwort and leeches were washed, sterilized, and freeze-dried respectively. The freeze-drying temperature was -50°C and the freezing time was 20 minutes to obtain 6% water content. Medicinal materials;

[0092] The medicinal materials were pulverized with a pulverizer to obtain a coarse powder, which was fed into an airflow pulverization device through an electromagnetic feeder, the speed of the classifier was 2300r / min, the feeding speed was 8kg / h, and pulverized for 20 minutes to obtain a traditional Chinese medicine powder.

[0093] Then freeze-dry the medicin...

Embodiment 2

[0096] Composition of raw materials (parts by weight): 150 parts of astragalus, 120 parts of rehmannia glutinosa, 130 parts of sealwort and 20 parts of leeches.

[0097] The Chinese medicine composition is prepared according to the following method:

[0098] S1. Treatment of medicinal materials: Wash the fresh astragalus root, rehmannia glutinosa, sealwort and leech, freeze-dry them respectively, grind the medicinal materials with a pulverizer to obtain a coarse powder, and add it to the airflow pulverization device through the electromagnetic feeder, and the speed of the classifier is 2300r / min, the feed rate is 8kg / h, pulverized for 3h, the particle size of the obtained Chinese medicine powder is less than 10 μm, and it is set aside; the powders are mixed in proportion to be called Chinese medicine powder 2.

[0099] S2. Tablet pressing: add ethanol-water solution and microcrystalline cellulose to the broken wall powder of traditional Chinese medicine prepared in step S1, t...

Embodiment 3

[0101] Composition of raw materials (parts by weight): 130 parts of astragalus, 112 parts of rehmannia glutinosa, 117 parts of Polygonatum and 14 parts of leech.

[0102] The Chinese medicine composition is prepared according to the following method:

[0103] S1. Treatment of medicinal materials: Wash the fresh astragalus root, rehmannia glutinosa, sealwort and leech, freeze-dry them respectively, grind the medicinal materials with a pulverizer to obtain a coarse powder, and add it to the airflow pulverization device through the electromagnetic feeder, and the speed of the classifier is 2300r / min, the feeding speed is 8kg / h, pulverize for 2h to obtain Chinese medicine powder, the particle size of the medicine powder is less than 10 μm, and set aside; the powder is mixed in proportion, called Chinese medicine powder 3.

[0104] The freeze-drying temperature is -50 to -60°C, the freezing time is 20 to 40 minutes, and the medicinal material with a water content of 6% to 8% is ob...

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Abstract

The invention puts forward a traditional Chinese medicine composite, and a preparation method and an application thereof. The traditional Chinese medicine comprises 120-150 parts by weight of radix astragali powder, 110-120 parts by weight of radix rehmanniae recen powder, 110-130 parts by weight of rhizoma polygonati powder and 10-20 parts by weight of hirudo powder. The traditional Chinese medicine composite is obtained in a way that fresh radix astragali, radix rehmanniae recen, rhizoma polygonati and hirudo are independently frozen and dried and are subjected to superfine grinding and wall breaking, and the D50 of the obtained powder is smaller than 10[Mu]m. The traditional Chinese medicine composite can be used for preparing medicines capable of treating or preventing diabetes mellitus and complications thereof, has good efficacies on supplementing Qi, nourishing Yin, strengthening the body resistance, consolidating, promoting blood circulation to remove blood stasis and activating meridians to stop pain, can effectively treat diabetes mellitus and complications thereof and can realize the effects on lowering blood glucose and blood fat, improving microcirculation and addressing both symptoms and root causes.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating or preventing diabetes and its complications, a preparation method and application thereof. Background technique [0002] Diabetes is a metabolic disease characterized by hyperglycemia, which can be divided into type I diabetes and type II diabetes, manifested as symptoms of polydipsia, polyphagia, polyuria, and weight loss. Usually manifested as elevated fasting blood glucose, glycosylated serum protein, urinary protein, triglyceride, and total cholesterol, pancreatic β-cell damage, islet dysfunction, and insufficient insulin secretion. Long-term hyperglycemia will increase oxidative stress, change the structure and function of proteins and lipids, lead to glycosylation of proteins and activation of polyols, increase reactive oxygen species to promote the production of inflammatory cytokines, stimulate ...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61P3/10A61P9/00A61P13/12A61P17/02A61P27/02A61K35/62
CPCA61K36/481A61K36/804A61K36/8969A61K35/62A61P3/10A61P9/00A61P13/12A61P17/02A61P27/02A61K2300/00
Inventor 罗均锦黄深润李辉庆肖秀群赵晓静
Owner 广东合威制药有限公司
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