Biological two-parameter sensor based on photonic crystal fiber
A photonic crystal fiber and dual-parameter technology, which is applied in the field of biosensing, can solve the problems of single detection parameter and low sensitivity of biosensors, and achieve the effect of safe signal transmission, high sensitivity and good stability
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Embodiment 1
[0032] Use the COMSOL Multiphysics simulation software to establish a photonic crystal fiber geometric model and perform numerical simulation and mode analysis, and record the effective refractive index neff of the core mode at different wavelengths, and the loss characteristics represented by its imaginary part Im(neff) are as follows image 3 As shown, the ambient temperature is set at 20°C, and the refractive index of the biological fluid to be tested is 1.37. Two resonant loss peaks W1 and W2 are generated in the output spectrum, and the loss peak W1 is smeared with the The result of the plasmon resonance channel on the coated gold surface of the biological fluid is used to detect the concentration of the biological fluid to be measured; the loss peak W2 is the result of the directional coupling channel of the photonic crystal fiber core filled with a temperature-sensitive medium, which is used for temperature detection .
example 2
[0034] Such as Figure 4 As shown, when the external temperature is 20°C, the loss of the core guided mode varies with the wavelength under different refractive indices of the same biological liquid to be tested. By comparison, it is found that when the refractive index of the liquid to be tested changes from 1.34 to 1.37, the resonance loss peak moves to the short wavelength direction with the increase of the refractive index, and a blue shift occurs, and the loss peak increases slightly. A, B, C, D and E represent the resonance peaks under different refractive indices of the same liquid to be measured, respectively. The resonance wavelength λr corresponding to the resonance loss peak is more sensitive to the change of the refractive index of the liquid to be tested. Therefore, by using this characteristic, the change of the refractive index of the liquid to be tested can be analyzed by comparing the drift of λr, and then the change of the concentration of the liquid to be te...
example 3
[0036] Figure 6 It shows the relationship between the resonant wavelength and the refractive index of the liquid to be measured. It can be found that the resonant wavelength and the refractive index of the liquid to be measured are in good linearity and sensitivity when the plasmon resonance of the coated gold surface coated with the liquid to be measured is 1.34 to 1.37. Sensitivity in the range of refractive index changes up to
[0037]
[0038] where S RIU is the sensitivity under the condition of refractive index, λ is the wavelength, and RIU is the refractive index.
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