Nano porous gold enzyme-free flexible sensing electrode for detecting glucose through sweat, and preparation method and application thereof

Abstract

The invention provides a nano porous gold enzyme-free flexible sensing electrode for detecting glucose through sweat, and a preparation method and application thereof. The invention provides a three-electrode coplanar integrated enzyme-free glucose sensing electrode, nano porous gold with high catalytic activity is combined with a fine interdigital electrode through electrodeposition, and a feasible method for electrodeposition of a nano material in a microelectrode area is provided. The nano porous gold modified flexible sensing electrode provided by the invention has higher sensitivity, extremely low detection limit, wider detection range and excellent stability and anti-interference performance, wherein the detection limit is 0.55 micrometers, in the detection ranges of 0.001-2.50mM and2.50-10.0mM, the electrode respectively has high sensitivity of 1297 mu A / mM.cm2 AND 854.7 mu A / mM.cm2.

Description

technical field [0001] The invention belongs to the field of sensors for glucose detection, and relates to a preparation method of a nanoporous gold (NPG) flexible sensing electrode for non-enzyme detection of glucose, in particular to the application of the sensing electrode in rapid glucose detection. Background technique [0002] Diabetes is a disease caused by the lack of insulin secreted by the human pancreas or the ineffective use of insulin. In recent decades, the incidence of diabetes has been increasing, and it has been listed as one of the four major non-communicable diseases. Diabetes is a chronic disease that can cause various complications such as vision loss, renal failure, retinopathy, and stroke. Therefore, the effective detection and treatment of diabetes has attracted widespread attention from the society. [0003] Studies have shown that strict control of blood sugar can protect the life and health of diabetic patients and effectively prevent complication...

AI Technical Summary

Problems solved by technology

However, this method needs to be prepared at high temperature, and the process conditions are complicated, the preparation cost is high, and the method of blood detection is more cumbersome than in vitro detection.

[0008] Moreover, the complex structure of interdigitated electrodes poses a great challenge to the loading of active materials. At present, the preparation of active material slurry and interdigitated electrodes by screen printing is a common method. However, this method has limitations on the slurry. And it is difficult to control the line width and distance of the interdigitated electrodes, and it is easy to cause electrode damage. Therefore, how to electrodeposit active materials in a small area is an urgent problem to be solved.

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