Filler for medical plastic surgery and its preparation method and application

Abstract

The invention provides a filler for medical plastic surgery and a preparation method and application thereof. The preparation method comprises the steps: a swollen biomaterial is wrapped with albumin,and then the albumin is solidified through formaldehyde and glutaraldehyde; and preferably, the preparation method comprises the step that the biomaterial swollen through normal saline is sequentially treated through a human serum albumin solution, a formaldehyde solution, a glutaraldehyde solution and an ethyl alcohol solution. The filler provided by the invention is better than existing frequently-used silica gel, hyaluronic acid, creotoxin, normal saline bag, decellularized tissue and the like, the filler has good compatibility with a human body and can also continuously play a role in plastic surgery, the phenomenon of liquefaction is avoided, and side effects are avoided; and the preparation method is simple and suitable for large-scale production.

Description

technical field [0001] The invention relates to the field of medical plastic surgery, and more specifically, to a filler for medical plastic surgery and its preparation method and application. Background technique [0002] Due to the love of beauty and the development of science and technology, the medical plastic surgery and cosmetology industry has developed rapidly in recent years. The main treatment scope includes trauma, disease, congenital or acquired tissue or organ defects and deformities, and the treatment includes repair and reconstruction. , which is essential to use fillers. [0003] At present, products such as silica gel, hyaluronic acid (Restylane), botox (Botox), saline bags, autologous fillers, and decellularized tissue are commonly used in medical plastic surgery and beauty industries as fillers to be implanted in the body. Four situations will occur when these substances enter the body : The first case is that it is not integrated with the body and is alw...

AI Technical Summary

Problems solved by technology

[0003] At present, products such as silica gel, hyaluronic acid (Restylane), botox (Botox), saline bags, autologous fillers, and decellularized tissue are commonly used in medical plastic surgery and beauty industries as fillers to be implanted in the body. Four situations will occur when these substances enter the body : The first case is that it is not integrated with the body and is always in a free state. Silica gel, polymethyl methacrylate (Artecoll), and saline bags belong to this type of product; the second case is that it is effective for a short time and is difficult to last To maintain the effect, such products include hyaluronic acid, botulinum toxin, etc.; the third case is autologous fillers, such as cartilage, adipose tissue, skin and subcutaneous tissue, etc., which mainly use autologous cells and tissues in accordance with the model of tearing apart the east to make up for the west. Operation, plastic surgery can be effective for a long time, but this is a case-by-case treatment, unable to carry out quality control and mass production, it is difficult to widely promote and apply; the fourth situation is that it can be integrated with the body and can last for a long time, but after a period of time , filler liquefaction, obvious side effects, such as allogeneic decellularized tissue (Cymetra), synthetic hydroxyapatite (Radiesse), synthetic collagen, etc.