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Compound amino acid dipeptide injection and preparation method thereof

A compound amino acid and injection technology, applied in the field of biomedicine, can solve the problems of poor wound healing promotion effect, etc., and achieve the effect of speeding up the recovery time, better effect, and promoting healing effect.

Inactive Publication Date: 2020-01-17
天津金耀集团湖北天药药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The present invention proposes a compound amino acid dipeptide injection and its preparation method to solve the problem of poor wound healing promotion effect on patients raised in the above-mentioned background technology

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] The present invention proposes a compound amino acid dipeptide injection, the weight of which is in the following proportions:

[0023] 4 parts alanine, 2 parts arginine, 0.7 parts aspartic acid, 0.9 parts glutamic acid, 1 part histidine, 0.9 parts isoleucine, 1.6 parts leucine, 2.5 parts lysine acetate , 0.9 parts methionine, 1.2 parts phenylalanine, 1 part proline, 0.8 parts serine, 0.9 parts threonine, 0.3 parts tryptophan, 0.85 parts valine, 8 parts glycyl glutamine Amide, 0.75 parts of glycyltyrosine, 0.5 parts of pH regulator, 20 parts of water, 0.1 part of adsorbent.

[0024] The mass ratio of glutamic acid, isoleucine, methionine and threonine is 1:1:1:1.

[0025] The mass ratio of histidine to proline is 1:1.

[0026] The pH regulator is citric acid.

[0027] The adsorbent is medicinal charcoal.

[0028] The present invention also proposes a preparation method of compound amino acid dipeptide injection, comprising the steps of:

[0029] S1: Add injection w...

Embodiment 2

[0037] The present invention proposes a compound amino acid dipeptide injection, the weight of which is in the following proportions:

[0038] 5 parts alanine, 3 parts arginine, 1.2 parts aspartic acid, 1 part glutamic acid, 2 parts histidine, 1 part isoleucine, 2.6 parts leucine, 3.5 parts lysine acetate , 1 part methionine, 2.2 parts phenylalanine, 2 parts proline, 1.3 parts serine, 1 part threonine, 0.8 parts tryptophan, 0.95 parts valine, 10 parts glycyl glutamine Amide, 1.25 parts of glycyltyrosine, 1 part of pH regulator, 24 parts of water, 0.15 parts of adsorbent.

[0039] The mass ratio of glutamic acid, isoleucine, methionine and threonine is 1:1:1:1.

[0040] The mass ratio of histidine to proline is 1:1.

[0041] The pH regulator is citric acid.

[0042] The adsorbent is medicinal charcoal.

[0043] The present invention also proposes a preparation method of compound amino acid dipeptide injection, comprising the steps of:

[0044] S1: Add injection water to th...

Embodiment 3

[0052] The present invention proposes a compound amino acid dipeptide injection, the weight of which is in the following proportions:

[0053]6 parts alanine, 4 parts arginine, 1.7 parts aspartic acid, 1.1 parts glutamic acid, 3 parts histidine, 1.1 parts isoleucine, 3.6 parts leucine, 4.5 parts lysine acetate , 1.1 parts methionine, 3.2 parts phenylalanine, 3 parts proline, 1.8 parts serine, 1.1 parts threonine, 1.3 parts tryptophan, 1.05 parts valine, 12 parts glycyl glutamine Amide, 1.75 parts of glycyltyrosine, 1.5 parts of pH regulator, 30 parts of water, 0.2 parts of adsorbent.

[0054] The mass ratio of glutamic acid, isoleucine, methionine and threonine is 1:1:1:1.

[0055] The mass ratio of histidine to proline is 1:1.

[0056] The pH regulator is citric acid.

[0057] The adsorbent is medicinal charcoal.

[0058] The present invention also proposes a preparation method of compound amino acid dipeptide injection, comprising the steps of:

[0059] S1: Add injectio...

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Abstract

The invention discloses a compound amino acid dipeptide injection. The compound amino acid dipeptide injection is prepared from the following components in pats by weight: 4-8 parts of alanine, 2-6 parts of arginine, 0.7-2.7 parts of aspartic acid, 0.9-1.3 parts of glutamic acid, 1-5 parts of histidine, 0.9-1.3 parts of isoleucine, 1.6-5.6 parts of leucine, 2.5-6.5 parts of lysine acetate, 0.9-1.3parts of methionine, 1.2-5.2 parts of phenylalanine, 1-5 parts of proline, 0.8-2.8 parts of serine, 0.9-1.3 parts of threonine, 0.3-2.3 parts of tryptophan, 0.85-1.35 parts of valine, 8-16 parts of glycylglutamine, 0.75-2.75 parts of glycyltyrosine, 0.5-2.5 parts of a PH regulator, 20-38 parts of water and 0.1-0.3 part of an adsorbent. The invention further provides a preparation method of the compound amino acid dipeptide injection. Glutamine is generated by the glycyltyrosine, the generated glutamine repairs a postoperative wound, compound amino acid has a better effect of promoting wound healing, the healing time of a postoperative patient is shortened, and the healing promoting effect is better.

Description

technical field [0001] The invention relates to the technical field of biomedicine, in particular to a compound amino acid dipeptide injection and a preparation method thereof. Background technique [0002] Amino acid is the basic unit of protein molecules in organisms. It is closely related to the life activities of organisms. It is one of the essential nutrients in organisms. The digestion and absorption of protein in the body is completed through amino acids. The need for amino acids is actually the need for amino acids. A variety of amino acids (including dipeptides, etc.) are properly proportioned to form a compound amino acid preparation, which can improve protein metabolism in the body and correct negative nitrogen balance. The existing amino acid nutrient solution is beneficial to wound healing of patients. The promotion effect is poor. Contents of the invention [0003] The present invention proposes a compound amino acid dipeptide injection and a preparation met...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K31/198A61K31/4172A61K31/401A61K31/405A61P17/02
CPCA61K9/0019A61K9/08A61K31/198A61K31/401A61K31/405A61K31/4172A61P17/02A61K2300/00
Inventor 曹琦
Owner 天津金耀集团湖北天药药业股份有限公司
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