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Traditional Chinese medicine extract of Jindan with anti-allergic function and preparation method and application of Jindan

The technology of an extract and golden elixir is applied in the field of jindan anti-allergic traditional Chinese medicine extract and its preparation, which can solve the problems of ambiguity and poor anti-allergic effect, and achieve less irritation, which is beneficial to anti-allergic and relieves therapeutic hormones. Effects of dependent dermatitis

Pending Publication Date: 2020-02-07
上海国伊康美健康管理有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although many plant extracts are claimed to have more or less anti-allergic effects, whether these traditional Chinese medicines can extract a sufficient amount of effective anti-allergic ingredients so that they can be added to cosmetics to produce good anti-allergic effects is not sure. clearly
At the same time, most of the traditional Chinese medicine extracts added to existing cosmetics are extracts of single traditional Chinese medicines, and the anti-allergic effect is not good.
How to compound a multi-component Chinese medicine compound, and which extraction method can most effectively extract the effective anti-allergic active ingredients in the Chinese medicine compound, still need to be further studied

Method used

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  • Traditional Chinese medicine extract of Jindan with anti-allergic function and preparation method and application of Jindan
  • Traditional Chinese medicine extract of Jindan with anti-allergic function and preparation method and application of Jindan
  • Traditional Chinese medicine extract of Jindan with anti-allergic function and preparation method and application of Jindan

Examples

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Effect test

Embodiment 1

[0047] Embodiment 1, the preparation of Jindan Antiallergic Chinese Medicine Extract

[0048] In this example, Jindan Antiallergic Chinese Medicine Extract Formula 1 is used to prepare Jindan Antiallergic Chinese Medicine Extract, which includes the following steps:

[0049] (1), crush the raw materials of the formula into granules, pass through a 200-400 mesh sieve, stir and mix evenly to obtain mixed granules, then add an aqueous ethanol solution with a mass ratio of 1:10 (volume percentage of ethanol is 50%) , soaked for 2 hours to obtain the soaking solution;

[0050] (2) Ultrasonic extraction is carried out on the soaking liquid in step (1), the ultrasonic frequency is 30kHz, the ultrasonic temperature is 30°C, the ultrasonic time is 30min, the number of ultrasonic waves is 3 times, and after centrifugation (centrifugation speed 3000rpm, centrifugation time 20 minutes) ), take the supernatant clear night to obtain the ultrasonic extraction solution;

[0051] (3), the ul...

Embodiment 2

[0054] Embodiment 2, the preparation of Jindan Antiallergic Chinese Medicine Extract

[0055] In this embodiment, Jindan Antiallergic Chinese Medicine Extract Formula 2 is used to prepare Jindan Antiallergic Chinese Medicine Extract, which includes the following steps:

[0056] (1) Grind the raw materials in the formula into granules, pass through a 200-400 mesh sieve, stir and mix evenly to obtain mixed granules, then add deionized water with a mass ratio of 1:20, and soak for 3 hours to obtain a soaking solution ;

[0057] (2) Ultrasonic extraction of the soaking liquid in step (1), controlling the ultrasonic frequency to 50kHz, ultrasonic temperature: 45°C, ultrasonic time: 30min, ultrasonic times: 5 times, after centrifugal treatment (centrifugal speed 3000rpm, centrifugal time 20 minutes) to get the supernatant clear night to obtain the ultrasonic extract;

[0058] (3), the ultrasonic extraction solution of step (2) is filtered with a microporous membrane of 1 μm, and t...

Embodiment 3

[0061] Embodiment 3, the preparation of Jindan Antiallergic Chinese Medicine Extract

[0062] In this example, Jindan Antiallergic Chinese Medicine Extract Formula 3 is used to prepare the compound Chinese medicine extract, which includes the following steps:

[0063] (1), crush each raw material drug of formula quantity into granules, after passing through 200~400 mesh sieves, stir and mix evenly to obtain mixed granules, then add the ethanol aqueous solution that mass ratio is 1:20 (volume percentage of ethanol is 70%) , soaked for 1 hour to obtain the soaking solution;

[0064] (2) Ultrasonic extraction is carried out on the soaking liquid in step (1), the ultrasonic frequency is 40kHz, the ultrasonic temperature is 25°C, the ultrasonic time is 15min, the ultrasonic times: 3 times, after centrifugation (3000rpm centrifugal speed, 20 minutes centrifugal time) ), get the supernatant to obtain the ultrasonic extraction solution;

[0065] (3), the ultrasonic extraction soluti...

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Abstract

The invention discloses a preparation method of a traditional Chinese medicine extract of Jindan with anti-allergic function. The preparation method comprises the following steps: (1) pulverizing thefollowing raw material medicine in parts by weight: 15-30 parts of baikal skullcap roots, 6-15 parts of sophora flavescens, 5-10 parts of coptis rhizomes, 3-8 parts of phellodendron barks, 10-20 partsof smilax glabra rhizomes, 15-30 parts of honeysuckle flowers, 8-20 parts of peony root barks, 5-15 parts of cnidium seeds, and 5-15 parts of broom cypress fruits, then conducting mixing evenly, adding an appropriate amount of solvent to soak the mixture, and obtaining a soaking solution; (2) conducting low-temperature ultrasonic extraction of the soaking solution, obtaining an ultrasonic extraction solution, conducting centrifugal separating, filtering by a microporous membrane, and concentrating under pressure through a reverse osmosis membrane, and obtaining a refined extract; and (3) drying the refined extract into powder or adding an appropriate amount of 1, 3-propanediol, 1, 3-butanediol or glycerin. According to the present invention, the traditional Chinese medicine extract of Jindan with anti-allergic function generates significant synergistic effects on anti-inflammatory and anti-allergic effects, simultaneously effectively relieves and treats hormone-dependent dermatitis, has soothing and anti-oxidation effects, and is especially suitable for sensitive skins, weak skin barrier and people suffering from hormone-dependent dermatitis.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and relates to a Jindan anti-allergic traditional Chinese medicine extract and a preparation method and application thereof. Background technique [0002] As the largest organ of the human body, the skin plays a vital role in the health of the human body. According to domestic epidemiological surveys, the incidence of allergic diseases in my country in 2010 was 37.3%, of which the sensitive muscle population was about 3%. And increase at a rate of 23 times every 10 years. Sensitive skin (Sensitive Skin, SS) is a kind of skin with high reactivity, poor tolerance and even allergies, that is, a skin condition with subjective sensory symptoms induced by susceptibility to various factors. It is generally believed in medicine that SS is not a skin disease, but a skin condition. With the intensification of environmental pollution, the development of cosmetic diversity and the improvement of people's ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/9794A61K8/34A61Q19/00
CPCA61K8/9789A61K8/9794A61K8/345A61Q19/00A61Q19/005A61K2800/805A61K2800/82A61K2800/5922A61K2800/592
Inventor 张靖华张和平王莉娜王一宇刘畅
Owner 上海国伊康美健康管理有限公司
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