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A preparation method of whole powder compression tablet of Yiqiweixue Tablet

A technology of all-powder tableting and benefiting Qi, which is applied in the field of medicine, can solve problems such as difficult granulation, long process flow, and large loss, and achieve the effects of low disintegration, shortened process flow, and moderately low hardness

Active Publication Date: 2021-10-22
GUANGDONG HONGSHANHU PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the preparation method of wet granulation is not easy to granulate after adding a binder, and it needs to be dried twice before it can be further made into Yiqiweixue Tablets. The process is long and the loss is large.

Method used

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  • A preparation method of whole powder compression tablet of Yiqiweixue Tablet
  • A preparation method of whole powder compression tablet of Yiqiweixue Tablet
  • A preparation method of whole powder compression tablet of Yiqiweixue Tablet

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A preparation method for whole powder tableting of Yiqiweixue Tablets, comprising the following steps:

[0025] (S1), take 12 parts of lubricant powder by weight and pass through a 100-mesh sieve to obtain the processed lubricant powder for subsequent use;

[0026] (S2), take 452 parts of Yiqi Weixue extract dry powder, 103 parts of binder powder and 3 parts of talcum powder by weight, pass through 80 mesh sieve respectively, then mix evenly, and then pass 40 mesh sieve to obtain mixed powder;

[0027] (S3), mix the treated lubricant powder obtained in step (S1) and the mixed powder obtained in step (S2), pass through a 40-mesh sieve, and press into tablets to obtain Yiqiweixue Tablets.

[0028] The lubricant powder is prepared by mixing silicon dioxide and magnesium stearate in a weight ratio of 9:3.

[0029] The binder powder is prepared by mixing microcrystalline cellulose, hydroxypropyl cellulose and sodium carboxymethyl cellulose in a weight ratio of 57:34:12.

...

Embodiment 2

[0034] A preparation method for whole powder tableting of Yiqiweixue Tablets, comprising the following steps:

[0035] (S1), take 10 parts by weight of the lubricant powder and pass through a 90-mesh sieve to obtain the treated lubricant powder for subsequent use;

[0036] (S2), take 450 parts of Yiqi Weixue extract dry powder and 99 parts of binder powder by weight, respectively pass through a 70-mesh sieve, then mix evenly, and then pass through a 30-mesh sieve to obtain a mixed powder;

[0037] (S3), mix the treated lubricant powder obtained in step (S1) and the mixed powder obtained in step (S2), pass through a 30-mesh sieve, and press into tablets to obtain Yiqiweixue Tablets.

[0038] The lubricant powder is prepared by mixing silicon dioxide and magnesium stearate in a weight ratio of 7:2.

[0039] The binder powder is prepared by mixing microcrystalline cellulose, hydroxypropyl cellulose and sodium carboxymethyl cellulose in a weight ratio of 55:32:10.

[0040] The m...

Embodiment 3

[0043] A preparation method for whole powder tableting of Yiqiweixue Tablets, comprising the following steps:

[0044](S1), take 14 parts of lubricant powder by weight and pass through a 110-mesh sieve to obtain the treated lubricant powder for subsequent use;

[0045] (S2), take 468 parts of Yiqi Weixue extract dry powder, 117 parts of binder powder and 4 parts of talcum powder by weight, respectively pass through a 90-mesh sieve, then mix evenly, and then pass through a 50-mesh sieve to obtain a mixed powder;

[0046] (S3), mix the treated lubricant powder obtained in step (S1) and the mixed powder obtained in step (S2), pass through a 50-mesh sieve, and press into tablets to obtain Yiqiweixue Tablets.

[0047] The lubricant powder is prepared by mixing silicon dioxide and magnesium stearate at a weight ratio of 10:4.

[0048] The binder powder is prepared by mixing microcrystalline cellulose, hydroxypropyl cellulose and sodium carboxymethyl cellulose in a weight ratio of 6...

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Abstract

The present invention relates to the field of medical technology, in particular to a preparation method of full powder tableting of Yiqiweixue Tablets, comprising the following steps: (S1), taking 10-14 parts of lubricant powder in parts by weight and passing through a 90-110 mesh sieve, Obtain the lubricant powder after treatment, standby; (S2), take 450-468 parts of Yiqi Weixue extract dry powder, 99-117 parts of binder powder and 0-4 part of talcum powder by weight, pass 70-46 parts respectively 90 mesh sieve, then mix evenly, and then pass through a 30-50 mesh sieve to obtain a mixed powder; (S3), mix the treated lubricant powder and mixed powder and pass through a 30-50 mesh sieve, and tablet to obtain Qiwei blood sheet. The preparation method can reduce the production process of the Yiqiwei Blood Tablets, shorten the technical process, improve production efficiency, thereby reducing the production cost, and at the same time solve the problems of long technical process and large loss of the existing wet method of Yiqiwei Blood Tablets.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a method for preparing whole powder compressed tablets of Yiqiweixue Tablets. Background technique [0002] Iron deficiency anemia is one of the nutritional deficiency diseases with a relatively high incidence rate, and its incidence rate is significantly increased in developing countries, economically underdeveloped areas, infants, and women of childbearing age. Whether in urban or rural areas, children, adults or the elderly can occur. Iron-deficiency anemia is often characterized by sallow or pale complexion, dizziness, fatigue, lack of breath, loss of appetite, spontaneous sweating, pale lips and tongue, thin and weak pulse, growth retardation in children, and susceptibility to the disease due to reduced immune function Various diseases seriously affect the physical fitness, and the prevention and treatment of malnutrition and iron deficiency anemia has become the focus of ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K47/04A61K47/02A61K47/12A61K47/38A61K36/725A61P7/06A61K35/14
CPCA61K9/2009A61K9/2013A61K9/2054A61K9/2095A61K35/14A61K36/481A61K36/725A61P7/06A61K2300/00
Inventor 方燕秋
Owner GUANGDONG HONGSHANHU PHARM CO LTD