Application of lanthanum-modified chiral nematic mesoporous silicon catalyst in synthesis of borneol

Abstract

The invention discloses an application of a lanthanum-modified chiral nematic mesoporous silicon catalyst in synthesis of borneol, and lanthanum-modified chiral nematic mesoporous silicon can catalyzeand synthesize borneol with high selectivity in catalyzing an esterification-saponification reaction of alpha-pinene. According to the method, the problems that in the prior art, alpha-pinene is usedas a raw material for the esterification-saponification reaction, the yield of borneol is low, the catalyst selectivity is poor, and the catalyst is difficult to reuse are solved; according to the present invention, with the catalyst, the borneol can be directly obtained, the difficulty of the borneol separation is avoided, and the preparation process is simple, and is suitable for industrial production and market promotion and application.

Description

technical field [0001] The invention relates to the application of a lanthanum-modified chiral nematic mesoporous silicon catalyst in the selective synthesis of borneol, which belongs to the field of chemical industry. Background technique [0002] Turpentine is a renewable essential oil that contains a variety of terpenes, the main components of which are α-pinene and β-pinene, which are isomers of each other, and the content of α-pinene is more than 90%. Turpentine can be directly used in medicine and as a solvent, but more importantly, it is used in fine chemistry, such as synthesizing daily chemical fragrances, pharmacologically active substances, agricultural and household biologically active substances and functional materials, etc. Turpentine can be processed through esterification-saponification Obtain high-value borneol; borneol has isomers, divided into orthoborneol and isoborneol, because the side effects of isoborneol are far greater than those of orthoborneol, a...

AI Technical Summary

Problems solved by technology

Turpentine can be directly used in medicine and as a solvent, but more importantly, it is used in fine chemistry, such as synthesizing daily chemical fragrances, pharmacologically active substances, agricultural and household biologically active substances and functional materials, etc. Turpentine can be processed through esterification-saponification Obtain high-value borneol; borneol has isomers, divided into orthoborneol and isoborneol, because the side effects of isoborneol are far greater than those of orthoborneol, and due to the properties of these two substances and their Similar, there is no effective separation method, which is not conducive to the application of orthoborneol, so the use value of orthoborneol greatly exceeds that of isoborneol; orthoborneol can be used for medicine, fine spices, etc.

[0003] At present, in the research on the synthesis of borneol from α-pinene, boric anhydride and metaboric acid catalysts are the most commonly used in industry, and the production technology is mature, but the reaction process Medium heat exotherm is violent, is not easy to control, and the productive rate of borneol is unsatisfactory, and isoborneol accounts for a higher proportion in borneol total amount, generates a large amount of isoborneols

According to current literature reports, the solid superacid S2O82- / ZrO2 prepared by precipitation method -NiO catalyst, using anhydrous oxalic acid as esterification agent, synthesize borneol by esterification-saponification two-step method, the yield of borneol is as high as 55.8%, and the content of orthoborneol in the total borneol can reach 77.01%. This method Although a high proportion of orthoborneol has been obtained, the reaction is stable, and the catalyst is easy to separate, but there is still isoborneol in the product, which still faces the problem of separation, and S2O8 sub>2- is an active component that has potential safety hazards and is prone to explosion, which is not conducive to industrialization; in the application number 201910589375.9, Al2O3 / CNMS-SO3H is a catalyst for esterification and saponification to generate borneol. The highest yield of borneol is 53.94%, and the content of orthoborneol is 70.5%, but it still needs to face isoborneol Separation problem, not conducive to the recycling of orthoborneol

Images