Drug Application of Epimedin C in Treating Diabetic Liver Injury

A technology of diabetes and epimedin, which is applied in the application field of preparing drugs for the treatment of diabetic liver damage, and can solve the problem of not fully considering the taste and bioavailability of drugs, and it is difficult to reveal the substances of Epimedium used in the treatment of diabetes and its complications Fundamental and other issues to achieve the effect of improving liver oxidative stress, alleviating lipid metabolism disorders, and increasing HDL-C levels
CN111494360BActive Publication Date: 2021-02-12陕西新修本草健康产业有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
陕西新修本草健康产业有限公司
Publication Date
2021-02-12

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Abstract

The invention discloses the drug application of epimedin C for treating diabetic liver injury, and belongs to the technical field of biomedicine. The present invention discloses for the first time that epimedin C can increase the level of high-density lipoprotein cholesterol in the liver of diabetic model animals, reduce the level of low-density lipoprotein cholesterol in the liver, alleviate the problem of lipid metabolism disorder, reduce liver index, and enhance superoxide dismutase in the liver , Glutathione peroxidase activity, reduce malondialdehyde content, improve liver oxidative stress state, maintain normal shape and structure of liver cells and tissues, reduce liver alanine aminotransferase and aspartate aminotransferase activity levels, and promote liver function repair, Therefore, it can be used to prepare medicines for treating diabetic liver damage. Epimedin C prepares a medicine for treating diabetic liver damage and uses it in the form of pharmaceutical preparations, including buccal tablets, coated tablets and hard capsules. The invention provides a basis for the treatment of diabetic liver damage, and also provides ideas for the deep development and utilization of epimedium resources.
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Description

technical field

[0001] The invention belongs to the technical field of biomedicine, and relates to the new effect of Epimedin C in treating complications of diabetic liver damage (abbreviated as diabetic liver damage), and its application in the preparation of drugs for treating diabetic liver damage. Background technique

[0002] In recent years, the incidence of diabetes has increased year by year, and it has become the third major disease that seriously endangers human life and health after cardiovascular and cerebrovascular diseases and tumors. Diabetic complications are an important cause of disability and death in patients. As an important organ of sugar and lipid metabolism, the liver has a very close relationship with diabetes. Diabetes may cause damage to the liver in many ways, leading to complications of liver damage. Due to the atypical clinical symptoms of diabetic liver injury and other reasons, it has not been paid much attention by the medical community in ...

Claims

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