Compound pharmaceutical composition for coronary heart disease
A composition and technology for coronary heart disease, which are applied in the directions of drug combinations, cardiovascular system diseases, active ingredients of heterocyclic compounds, etc., can solve the problem that there are no reports on the combined application of atorvastatin calcium and atraliuton in the literature, and no reports in the literature. Compound pharmaceutical composition, the effect of improving inflammation is not obvious, etc., to prevent and treat thrombosis and complications of formation, reduce high-sensitivity C-reactive protein and plasma interleukin, and stabilize the size of the effect.
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Embodiment 1
[0077] prescription:
[0078]
[0079]
[0080] Preparation process: Weigh atorvastatin calcium, atrileuton, lactose, carboxymethyl starch sodium, and hypromellose, mix them evenly, add water and mix them to make a soft material, pass through a 20-mesh sieve to make wet granules, and dry at 60°C , 20-mesh sieve, adding magnesium stearate, mixing, tableting, that is.
Embodiment 2
[0082] prescription:
[0083]
[0084] Preparation process: Weigh atorvastatin calcium, atrileuton, lactose, microcrystalline cellulose, low-substituted hydroxypropyl cellulose, and hypromellose, mix them evenly, add water to mix to make a soft material, and pass through a 20-mesh sieve. Wet granules, dried at 60°C, sieved with a 20-mesh sieve, added with magnesium stearate, mixed evenly, pressed into tablets, and obtained.
Embodiment 3
[0086] prescription:
[0087]
[0088]
[0089] Preparation process: Weigh atorvastatin calcium, atrileuton, lactose, starch, sodium carboxymethylcellulose, and hypromellose, mix evenly, add water to mix to make a soft material, pass through a 20-mesh sieve to make wet granules, Dry at 60°C, sieve through a 20-mesh sieve, add talcum powder, mix well, and press into tablets to obtain the product.
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