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Compound recipe cyclocarya paliurus leaf preparation

A technology of compound Qingqian and Qingqianliu, which is applied in pharmaceutical formulations, medical preparations containing active ingredients, plant raw materials, etc., can solve the problems of substandard blood pressure control, low awareness rate of diabetes, low treatment rate, etc. Fasting blood sugar level, improving symptoms of polydipsia, improving insulin resistance

Pending Publication Date: 2020-08-25
湖南清雅健康服务有限公司 +1
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AI Technical Summary

Problems solved by technology

In stark contrast to the huge population of people with diabetes, the status quo of diabetes treatment in my country is very worrying: the awareness rate of diabetes is low, the treatment rate is low, the treatment compliance rate is low, and the complications are high
Not only the compliance rate of blood sugar is low, but also the compliance rate of body weight and blood pressure is not satisfactory: 52.3% of patients fail to control blood sugar, 58.3% of patients are overweight, and 71.6% of patients fail to control blood pressure

Method used

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  • Compound recipe cyclocarya paliurus leaf preparation
  • Compound recipe cyclocarya paliurus leaf preparation
  • Compound recipe cyclocarya paliurus leaf preparation

Examples

Experimental program
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Effect test

Embodiment 1

[0026] 1.1 Drugs

[0027] 1.1.1 Qingqian Liuye (QQL) is tan dry extract powder, content: 8.83g crude drug / g dry extract powder; pueraria root (GG) is tan dry extract powder, content: 8.83g crude drug / g dry extract powder Extract powder; Compound Cyclocarya paliurus (HRLYQ-1, proportioning QQL:GG=1:0.25; HRLYQ-2, proportioning QQL:GG=1:0.5; HRLYQ-3, proportioning QQL:GG=1:1 ; HRLYQ-4, proportioning QQL:GG=1:2) is tan dry extract powder, content: 8.83g crude drug / g dry extract powder, batch number: 20161201, valid until December 01, 2018, from Hunan Provided by Heran Biotechnology Development Co., Ltd.

[0028] 1.1.2 Positive control drug: metformin hydrochloride tablets, produced by Sino-US Shanghai Bristol-Myers Squibb Pharmaceutical Co., Ltd., specification: 0.25g / tablet, batch number: 201511039, valid until April 2018. Indications: For patients with type 2 diabetes who are unsatisfied with simple diet control, especially those who are obese and accompanied by hyperinsuline...

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Abstract

The invention relates to a compound recipe cyclocarya paliurus leaf preparation. The compound recipe cyclocarya paliurus leaf preparation consists of cyclocarya paliurus leaf and radix puerariae, preferably, 8 parts by weight of the compound recipe cyclocarya paliurus leaf preparation contains 4 parts by weight of the cyclocarya paliurus leaf and 4 parts by weight of the radix puerariae. The invention also provides an application of the compound recipe cyclocarya paliurus leaf preparation to preparation of medicines for clinical treatment of type 2 diabetes. Through contrast of medicine administration effects between different kinds of medicine groups, the effects of the compound recipe cyclocarya paliurus leaf preparation for reducing blood sugar level, improving impaired sugar tolerance,reducing insulin level and improving insulin resistance indexes are obviously better than effects of single use of the cyclocarya paliurus leaves and effects of single use of the radix puerariae, comprehensive effects are notable, synergistic reactions are achieved when the cyclocarya paliurus leaves and the radix puerariae are united, and a new selection and a new thinking are provided for controlling diabetes.

Description

technical field [0001] The invention relates to a compound preparation for clinical treatment of type 2 diabetes. Background technique [0002] Diabetes mellitus (DM) is a chronic endocrine metabolic disease characterized by increased blood sugar caused by insufficient insulin secretion in the body or decreased sensitivity of target cells to insulin (insulin resistance). Diabetes and its complications have brought serious harm to human health, and have become the third leading cause of death after tumors and cardiovascular and cerebrovascular diseases. According to the ninth edition of the Diabetes Map released by the International Diabetes Federation (IDF) in 2019, the number of people with diabetes worldwide continues to rise, with an average global growth rate of 51%. Currently, 463 million adults aged 20-79 suffer from diabetes (11 1 in 1 individual is a diabetic), and it is estimated that by 2030, the number of diabetics will reach 578.4 million. Statistics show that ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/52A61P3/10
CPCA61K9/0095A61K36/488A61K36/52A61P3/10A61K2300/00
Inventor 徐康平吴建平姜德健陈祖辉孙惠惠刘学武李静黄露露欧赛玉常熙雯
Owner 湖南清雅健康服务有限公司
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