Micro-channel device processing technology

Abstract

The invention relates to a micro-channel device processing technology. The micro-channel device processing technology sequentially comprises the following steps: a three-dimensional data model of a micro-channel device to be processed is established in a computer; a photocuring printer is used for printing a concave plate and a plane plate according to the obtained three-dimensional data model, amicro-channel groove of the micro-channel device is printed in the surface of the concave plate, and the surface of the plane plate is flat and free of grooves; the concave plate and the plane plate are cleaned and dried; the processed concave plate and the processed plane plate are subjected to vacuum attaching, and the face, printed with the groove, of the concave plate is an attaching face; andafter vacuum attaching, UV curing treatment is carried out. Compared with the prior art, the technology adopting the low-cost photocuring printer for surface molding has the characteristics of beinggood in substrate flatness, high in manufacturing efficiency, easy to operate and low in cost, can be directly used for rapid manufacturing of single-piece or small-batch micro-channel devices, reduces the production cost of the micro-channel device, and is very efficient for single-piece or small-batch production of the micro-channel device.

Description

technical field [0001] The invention relates to the field of micro-channel device processing, in particular to a micro-channel device processing technology. Background technique [0002] Microchannel devices, also known as microfluidic chips, are important devices for biochemical analysis and medical diagnosis. They can integrate basic operating units such as sample preparation, reaction, separation, and detection in biological, chemical, and medical analysis processes into a micron-scale chip. , automatically complete the whole process of analysis. In terms of materials, it mainly includes glass chips, polymer chips, and metal chips, among which PDMS (polydimethylsiloxane) chips are the most common among polymer chips. [0003] The existing processing methods of micro-channel devices mainly include wet etching, photolithography and mold inversion, CNC (numerical control machine tool) equipment processing, mold opening and injection molding. Wet etching is mainly used to m...

AI Technical Summary

Problems solved by technology

Wet etching is mainly used to make glass chips. The processing accuracy of this process can reach 10-25 microns, but it usually needs to be processed in combination with photolithography and other processes. The processing cost is high and the operation is cumbersome.

Photolithography and inversion molding are mainly used in the processing of PDMS chips, and the processing accuracy can reach several microns, but this process requires the use of photoresist to make molds, the process is complicated, and the cost of molds is high

CNC equipment processing can be used to process polymer chips and metal chips. The minimum limit of the processing channel width is about 100 microns, but the price of CNC equipment itself is high

The mold opening and injection molding process is limited by the processing technology of the mold, which has restrictions on the shape of the channel, and it is difficult to process more complex structures, and using this method requires processing the mold first, which takes a long time and the mold is expensive, poor in flexibility, and chip structure changes It is necessary to re-open the mold, and the mold cost is relatively high

[0004] None of the above four types of processing techniques can take into account processing flexibility and low cost. The processing process is complicated and the configuration cost is high. It is mainly suitable for the batch production of micro-channel devices. The processing efficiency is low and the processing technology is cumbersome, so it is difficult to reduce the cost on the premise of meeting the needs of personalized customization

Images