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Traditional Chinese medicine composition for preventing or/and treating dyslipidemia and application of traditional Chinese medicine composition

A technology of dyslipidemia and composition, which is applied in the directions of drug combination, medical preparation containing active ingredients, pharmaceutical formula, etc., can solve the problem that the pathological state of "phlegm and blood stasis" in patients has not been significantly improved, and the prevention and control has not seen significant effect. Problems such as description, lack of sedative effect, etc.

Active Publication Date: 2020-12-11
GUANGANMEN HOSPITAL CHINA ACAD OF CHINESE MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, statins and fibrates are the main western medicines used clinically in Western medicine. Although these western medicines have a significant effect on improving dyslipidemia, there is no relevant description of the significant improvement in the pathological state of patients with "phlegm and blood stasis".
[0004] The existing medicines for the treatment of dyslipidemia with phlegm and blood stasis mainly include Zhibitai Capsules, Naoxintong Capsules, Yindanxinnaotong Soft Capsules and other common Chinese patent medicines. , "Red yeast rice" exerts the main effect of "activating blood circulation and removing blood stasis", but the two drugs have small blood-activating power and do not have the effect of dredging collaterals. There is no description of significant effect in the prevention and control of other complications in the next step; Naoxintong capsule focuses on "Qi deficiency and blood stasis" type cardiovascular and cerebrovascular diseases; Yindan Xinnaotong Soft Capsules focuses on "qi stagnation and blood stasis" type cardiovascular and cerebrovascular diseases. Some studies have found that it has the effect of improving hyperlipidemia, but it is not its main curative effect , and there is no significant effect description on the pathological elements of "phlegm turbidity"

Method used

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  • Traditional Chinese medicine composition for preventing or/and treating dyslipidemia and application of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for preventing or/and treating dyslipidemia and application of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for preventing or/and treating dyslipidemia and application of traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0070] Example 1 Preparation of Qilong Xuemaijian Granules

[0071] 1) Prepare raw materials according to the following weight ratio (unit: × 10g)

[0072] Coptidis 6, frankincense 9, myrrh 9, blood jellyfish 6, pinellia 9, whole melon 15, gynostemma 15, poria cocos 30, pangosaurus 15, among which frankincense is fried frankincense with vinegar; myrrh is myrrh fried with vinegar;

[0073] 2) Wash the raw materials Coptis chinensis, frankincense, myrrh, Pinellia, Trichosanthes, Gynostemma, Poria cocos, and pangosaurus, put them in a Chinese medicine multifunctional extraction kettle and mix well, add tap water to soak for 30 minutes (usually 20-90 minutes), Wherein, the ratio of the weight of tap water added to the weight (dry weight) of the medicinal material mixture is 9:1 (usually 1-15:1);

[0074] 3) Turn on the power supply of the multifunctional extraction kettle for heating, heat to 100°C, keep at this temperature for constant temperature extraction for 3 hours, and the...

Embodiment 2

[0083] Preparation of Example 2 Qilong Xuemaijian Pills

[0084] 1) Prepare raw materials according to the following weight ratio (unit: × 10g)

[0085] Coptis 3, frankincense 6, myrrh 9, blood jellyfish 9, pinellia 6, whole melon 15, gynostemma 15, poria cocos 30, pangosaurus 30

[0086] 2) After rinsing the medicinal materials Coptis chinensis, frankincense, myrrh, Pinellia, Gualou, Gynostemma pentaphyllum, Poria cocos, and pangosaurus, they were placed in a multifunctional extraction kettle of traditional Chinese medicine and mixed evenly, and then soaked in tap water for 60 minutes. The weight of the added tap water was equal to The weight (dry weight) ratio of the medicinal material mixture is 6:1;

[0087] 3) Turn on the power supply of the multi-functional extraction kettle for heating, heat to 80°C, keep at this temperature for constant temperature extraction for 5 hours, and then filter to obtain the first extraction solution for use;

[0088] 4) Then add tap water ...

Embodiment 3

[0093] Preparation of Example 3 Qilong Xuemaijian Tablets

[0094] 1) Prepare raw materials according to the following weight ratio (unit: × 10g)

[0095] Coptidis 9, frankincense 9, myrrh 6, blood dried fruit 3, pinellia 9, whole melon 9, gynostemma 30, poria cocos 15, pangosaurus 10

[0096] 2) Wash the raw materials Coptis chinensis, frankincense, myrrh, Trichosanthes, Gynostemma, Poria cocos, and mountain dragon, put them in a multi-functional extraction kettle of traditional Chinese medicine, add tap water to soak for 20 minutes (usually 20-90 minutes), wherein, the added tap water The ratio of the weight to the weight of the medicinal material mixture (dry weight) is 12:1 (usually 1-15:1);

[0097] 3) Turn on the power supply of the multifunctional extraction kettle for heating, heat to 80°C, keep at this temperature for constant temperature extraction for 5 hours, and then filter to obtain the first extraction solution for use;

[0098] 4) Then add tap water to the fi...

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Abstract

The invention discloses a traditional Chinese medicine composition for preventing or / and treating dyslipidemia and an application of the traditional Chinese medicine composition. The composition is prepared from the following raw materials: rhizoma coptidis, frankincense, myrrh, dragon's blood, processed pinellia tuber, fructus trichosanthis, fiveleaf gynostemma herbs, poria cocos and dioscorea nipponica. The traditional Chinese medicine composition is suitable for dyslipidemia conditions, especially hyperlipidemia symptoms, can be made into any common oral preparations and health-care products, has the efficacy of resolving phlegm, promoting blood circulation, reducing turbidity and dredging collaterals, improves dyslipidemia, achieves the purpose of remarkably reducing blood fat, and isespecially suitable for application of phlegm and blood stasis intermingled dyslipidemia.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and a preparation method thereof, in particular to a traditional Chinese medicine composition for treating dyslipidemia and a preparation method thereof, belonging to the field of traditional Chinese medicine. Background technique [0002] The disordered state of blood lipids can create an environment for the occurrence and development of atherosclerosis. Hyperlipidemia in adulthood increases the subsequent risk of coronary heart disease in a dose-dependent manner, and adults with long-term exposure to non-high-density lipoprotein cholesterol may increase the risk of future coronary heart disease. Multiple clinical trials of lipid-lowering drugs and epidemiological studies have also confirmed the relationship between serum cholesterol levels and the risk of coronary heart disease. At the same time, hyperlipidemia is also an important condition for the birth of diseases such as diabete...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K36/8945A61P3/06A61P9/10
CPCA61K36/718A61K36/324A61K36/328A61K36/889A61K36/896A61K36/8888A61K36/428A61K36/424A61K36/076A61K36/8945A61P3/06A61P9/10A61K2300/00
Inventor 胡元会崔翰明师帅张秋燕宋庆桥吴华芹魏艺耿彦婷
Owner GUANGANMEN HOSPITAL CHINA ACAD OF CHINESE MEDICAL SCI
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