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Anti-allergy composition as well as preparation method and application thereof

A kind of composition and seed technology, which is applied in the direction of drug combination, anti-inflammatory agent, pharmaceutical formula, etc., can solve the problems of general anti-allergic effect and failure to repair skin barrier function, achieve excellent anti-allergy, enhance skin barrier, maintain skin micro The effect of ecological balance

Pending Publication Date: 2020-12-22
中山大学深圳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the commercially available cosmetics with anti-allergic effects are usually added with inflammatory factor inhibitors (such as antihistamine anti-allergic agents), which can only simply cut off the allergic reaction without repairing the skin barrier function, and the anti-allergic effect is average. , and long-term use will also produce dependence and cause some other skin problems

Method used

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  • Anti-allergy composition as well as preparation method and application thereof
  • Anti-allergy composition as well as preparation method and application thereof
  • Anti-allergy composition as well as preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0042] An anti-allergic composition is fermented from the following components in mass percentage:

[0043] The raw material composition table of a kind of anti-allergic composition of table 1

[0044] raw material Mass percentage (%) Houttuynia cordata extract 16 Alpine Edelweiss Extract 22 Orange Peel Extract 21 Safflower Extract 12 glycerin 15 Butanediol 14

[0045] The preparation method of above-mentioned anti-allergic composition comprises the following steps:

[0046] 1) Fermentation: add Houttuynia cordata extract, Edelweiss alpine extract, orange peel extract, safflower extract, glycerol and butanediol into the fermentation tank, inoculate the brewer's yeast seed liquid, adjust the rotation speed of the fermentation tank to 220rpm, Dissolved oxygen DO value to 30%, 28 ℃ fermentation 12h;

[0047] 2) Sterilization: beat the fermented liquid in the fermenter, heat to 78°C for 35min;

[0048] 3) Filtration and concen...

Embodiment 2

[0050] An anti-allergic composition is fermented from the following components in mass percentage:

[0051] The raw material composition table of a kind of anti-allergic composition of table 2

[0052] raw material Mass percentage (%) Houttuynia cordata extract 16 Alpine Edelweiss Extract 22 Orange Peel Extract 21 Safflower Extract 12 Spring Elm Root Extract 1 glycerin 15 Butanediol 13

[0053] The preparation method of above-mentioned anti-allergic composition comprises the following steps:

[0054] 1) Fermentation: Add Houttuynia cordata extract, Edelweiss alpine extract, orange peel extract, safflower extract, spring elm root extract, glycerol and butanediol into the fermentation tank, inoculate brewer's yeast seed liquid to adjust fermentation Tank speed to 220rpm, dissolved oxygen DO value to 30%, fermentation at 28°C for 12h;

[0055] 2) Sterilization: beat the fermented liquid in the fermenter, heat to 78°C for...

Embodiment 3

[0058] An anti-allergic composition is fermented from the following components in mass percentage:

[0059] The raw material composition table of a kind of anti-allergic composition of table 3

[0060] raw material Mass percentage (%) Houttuynia cordata extract 16 Alpine Edelweiss Extract 22 Orange Peel Extract 21 Safflower Extract 12 Spring Elm Root Extract 1 Star Anise Extract 6 glycerin 15 Butanediol 7

[0061] The preparation method of above-mentioned anti-allergic composition comprises the following steps:

[0062] 1) Fermentation: Add Houttuynia cordata extract, Edelweiss alpine extract, orange peel extract, safflower extract, spring elm root extract, star anise extract, glycerol and butanediol into the fermentation tank, inoculate brewer's yeast The bacterial seed liquid was adjusted to 220 rpm in the fermentor, the DO value of dissolved oxygen was adjusted to 30%, and the fermentation was carried out at 2...

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Abstract

The invention discloses an anti-allergy composition as well as a preparation method and application thereof. The anti-allergy composition disclosed by the invention is prepared by fermenting the following components in percentage by mass of 12%-22% of a houttuynia cordata extract, 10%-25% of a leontopodium alpinum extract, 16%-26% of an orange peel extract, 8%-16% of a safflower extract, 0- 5% ofan elm root extract, 0-10% of an illicium verum extract, 0-12% of an ampelopsis grossedentata extract and the balance polyols. The preparation method of the anti-allergy composition comprises the following steps: 1) performing fermenting; 2) performing sterilizing; and 3) performing filtering and concentrating. The anti-allergy composition disclosed by the invention contains a plurality of small-weight active ingredients, is easy to absorb by skin, has excellent anti-allergy, anti-inflammatory and sedative effects, not only can be used for self-repairing and enhancing a skin barrier from a cell basal layer, but also can be used for adjusting the pH of the skin and maintaining the micro-ecological balance of the skin.

Description

technical field [0001] The present invention relates to an anti-allergic composition and its preparation method and application. Background technique [0002] With the intensification of air pollution and the increase of people's living pressure, the incidence of allergic skin diseases in humans is on the rise, and many respondents believe that they have sensitive skin. Sensitive skin is mostly found on the face, but it can also appear on other parts of the body, such as hands, feet, back, etc. Asians have thinner skin stratum corneum and are more prone to discomfort, so the most people have sensitive skin. [0003] Sensitive skin is a kind of skin with high reactivity, poor tolerance, and easy allergy. Medically, it is generally believed that sensitive skin is not a skin disease, but a skin condition. In recent years, with the improvement of people's health awareness, the perception rate and attention of sensitive skin have gradually increased. Sensitive skin has no evid...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61Q19/00A61P17/00A61P37/08A61P29/00
CPCA61K8/9789A61Q19/005A61P17/00A61P37/08A61P29/00A61K2800/85
Inventor 高理钱贾艳肖奇才杨芬谢程亮
Owner 中山大学深圳
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