Preparation method of D-panthenol

A technology of panthenol and aminopropanol, which is applied in the field of D-panthenol preparation, can solve the problems of poor quality of D-panthenol, high reaction requirements, and high quality requirements, etc., and achieve less impurities, high purity, and high purity. Effect
CN112174845APending Publication Date: 2021-01-05安徽泰格生物科技有限公司

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
安徽泰格生物科技有限公司
Publication Date
2021-01-05

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Abstract

The invention provides a preparation method of dianhydrol. The preparation method comprises the following steps: carrying out acylation reaction on D-pantoic acid lactone and 3-aminopropanol in a solvent to obtain a mixed solution containing D-panthenol, wherein the reaction temperature of the acylation reaction is 10-35 DEG C. The yield of the D-panthenol obtained by the preparation method is high, and the purity is high; meanwhile, the recovered solvent can be continuously used, and is safe and environment-friendly.
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Description

technical field

[0001] The invention belongs to the technical field of chemical synthesis and relates to a preparation method of D-panthenol. Background technique

[0002] Panthenol also known as provitamin B 5 , can be divided into 3 forms of DL-type, D-type and L-type, of which only the D-type has biological activity, and the L-type has no biological activity; D-panthenol is an optically active stereoisomer of ubiquinol body.

[0003] D-panthenol is the equivalent of D-pantothenic acid, which is widely used in medicine, food, feed and cosmetic industries. In the food industry, it is used as a nutritional supplement and fortifier to promote the metabolism of human protein, fat, and sugar, maintain skin and mucous membranes, improve hair luster, improve immunity, and prevent the occurrence of diseases; in the cosmetics industry, on the skin The care function of the hair is manifested as a deeply penetrating moisturizer, which stimulates the growth of epithelial cells, pro...

Claims

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