Method for preparing composite sponge for treating dry socket

A composite sponge, dry socket technology, applied in the direction of drug combination, pharmaceutical formulation, medical raw materials derived from bacteria, etc., can solve the problems of taking out the gauze again, slow wound healing, etc., to avoid inflammatory reaction, good therapeutic effect, good The effect of clinical application value

Active Publication Date: 2021-01-08
XUZHOU MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] Traditionally, iodoform gauze is used to prevent wound infection, but the use of io

Method used

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  • Method for preparing composite sponge for treating dry socket
  • Method for preparing composite sponge for treating dry socket
  • Method for preparing composite sponge for treating dry socket

Examples

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[0022]In order to make the above objectives, features, and advantages of the present invention more obvious and understandable, the specific embodiments of the present invention will be described in detail below in conjunction with specific embodiments.

[0023]In the following description, many specific details are explained in order to fully understand the present invention, but the present invention can also be implemented in other ways different from those described here, and those skilled in the art can do it without departing from the connotation of the present invention. Similar promotion, therefore, the present invention is not limited by the specific embodiments disclosed below.

[0024]Secondly, the “one embodiment” or “embodiment” referred to herein refers to a specific feature, structure, or characteristic that can be included in at least one implementation of the present invention. The appearances of "in one embodiment" in different places in this specification do not all ref...

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Abstract

The invention discloses a method for preparing a composite sponge for treating the dry socket. The method comprises the steps of: mixing staphylococcus aureus bacterial walls with sodium alginate solution, carrying out pre-freezing, and carrying out freeze-drying in a freeze dryer to obtain a staphylococcus aureus bacterial wall sponge; preparing mixed solution from gelatin, chitosan and calcium lactate; and adding the mixed solution into the staphylococcus aureus bacterial wall sponge, and carrying out freeze-drying after pre-freezing. According to the invention, the composite sponge is constructed by utilizing the typing change of immune cells after bacterial infection, adopting the bacterial walls of staphylococcus aureus and taking the chitosan, the gelatin and sodium alginate as matrices; research finds that the composite sponge prepared by the method disclosed by the invention not only can effectively regulate and control typing transformation of the local immune cells such as macrophages and the like to promotion of tissue repair, but also can effectively avoid the inflammatory reaction caused by bacterial infection, so that a good treatment effect is achieved on the dry socket; and the composite sponge has high clinical application value.

Description

technical field [0001] The invention belongs to the technical field of dry socket treatment, and in particular relates to a method for preparing a composite sponge for treating dry socket. Background technique [0002] Dry socket is one of the common complications after tooth extraction in oral surgery. It is more common in mandibular posterior teeth, especially after extraction of impacted mandibular third molars. Under normal circumstances, even with flap bone removal and tooth extraction, The wound pain will gradually disappear after 2 to 3 days. If severe pain occurs 2 to 3 days after tooth extraction, and the pain radiates to the ear-temporal region, submandibular area or the top of the head, and cannot be relieved by general analgesic drugs, it may have occurred. Dry socket. Clinical examination shows that the alveolar socket is empty, or there are corrupted blood clots, which are grayish white. The dead matter covering the wall of the alveolar socket has an odor, an...

Claims

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Application Information

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IPC IPC(8): A61K35/74A61K9/70A61K47/36A61K47/42A61P1/02A61P31/02A61P31/04
CPCA61K9/0063A61K9/7007A61K35/74A61K47/36A61K47/42A61P1/02A61P31/02A61P31/04
Inventor 姜力群崔飞艳孟箭王子尧杨玲张咪王云
Owner XUZHOU MEDICAL UNIV
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