Method for preparing high-solubility full-ingredient lonicera japonica extract

A technology of honeysuckle extract and high solubility, which is applied in the directions of non-active ingredients medical preparations, medical preparations containing active ingredients, functions of food ingredients, etc. , limit the scope of application, etc., to avoid the enrichment of aroma resin, good water solubility, and good solubility

Inactive Publication Date: 2021-02-05
劲牌持正堂药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, when the chlorogenic acid or flavonoids in honeysuckle are extracted and processed, due to the low boiling point of the volatile oil, during the concentration and drying of the honeysuckle extract, the volatile oil of the honeysuckle will be lost with the volatilization of the solvent, and the prepared extract No scent of honeysuckle
However, conventional volatile oil extraction devices can only extract and enrich volatile oil components, and cannot extract and separate other natural components.
And the volatile oil components are fat-soluble components, insoluble in water, which limits its application range

Method used

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  • Method for preparing high-solubility full-ingredient lonicera japonica extract

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] refer to figure 1 The flow process of a kind of highly soluble full-component honeysuckle extract preparation method comprises the following steps:

[0031] (1) Extraction: take 10Kg of pulverized honeysuckle raw materials, pass through a 30-mesh sieve, add 20 times the volume of pure water for extraction, extract three times, each time for 3 hours, the extraction temperature is 95 ° C, and combine the extracts.

[0032] (2) Disc centrifugation: use a disc centrifuge to centrifuge the above extract, and collect the centrifugate.

[0033] (3) Membrane filtration: the above centrifugal liquid is filtered by a ceramic membrane with a pore size of 1.4 μm.

[0034] (4) Concentration: The above-mentioned filtrate is concentrated under reduced pressure to a solid content of 61.3%, and the concentration temperature is required to be 40-75°C.

[0035] (5) Resin adsorption: The condensate in the extraction process of step (1) is returned to the extraction tank through XDA-8G re...

Embodiment 2

[0041] A preparation method of a highly soluble full-component honeysuckle extract, comprising the steps of:

[0042] (1) Extraction: Get 10Kg of pulverized honeysuckle raw materials, pass through a 30 mesh sieve, add 15 times the volume of 30% ethanol to heat and reflux for extraction, extract three times, each time for 2 hours, and combine the extracts.

[0043] (2) Disc centrifugation: use a disc centrifuge to centrifuge the above extract, and collect the centrifugate.

[0044] (3) Membrane filtration: the above centrifugal liquid is filtered by a ceramic membrane with a pore size of 0.05 μm.

[0045] (4) Concentration: the above-mentioned filtrate is concentrated under reduced pressure to a solid content of 68.5%, and the concentration temperature is required to be 40-75°C.

[0046] (5) Resin adsorption: the condensate in the extraction process of step (1) is returned to the extraction tank through XDA-8G resin to enrich and recover the aroma components in the condensate,...

Embodiment 3

[0052] A preparation method of a highly soluble full-component honeysuckle extract, comprising the steps of:

[0053] (1) Extraction: Get 10Kg of pulverized honeysuckle raw materials, pass through a 30 mesh sieve, add 8 times the volume of 50% ethanol to heat and reflux for extraction, extract three times, each time for 1 to 3 hours, and combine the extracts.

[0054](2) Disc centrifugation: use a disc centrifuge to centrifuge the above extract, and collect the centrifugate.

[0055] (3) Membrane filtration: the above centrifuge is filtered by a ceramic membrane with a pore size of 0.02.

[0056] (4) Concentration: The above-mentioned filtrate is concentrated under reduced pressure to a solid content of 70.3% or more, and the concentration temperature is required to be 40-75°C.

[0057] (5) Resin adsorption: The condensate in the extraction process of step (1) is returned to the extraction tank through LX-3020 resin to enrich and recover the aroma components in the condensate...

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Abstract

The invention discloses a method for preparing a high-solubility full-ingredient lonicera japonica extract. Through extracting chlorogenic acid and flavonoid ingredients from lonicera japonica by a conventional extracting tank, meanwhile, adsorbing condensate resulting from an extraction process through resin XDA-8G or LX-3020 to recover volatile oil ingredients from the condensate and then carrying out embedding and backfilling on the recovered volatile oil, the lonicera japonica extract prepared by the method is simultaneously rich in chlorogenic acid, flavonoid and volatile oil ingredientsand is high in water solubility and rich and durable in particular fragrance of the lonicera japonica.

Description

technical field [0001] The invention relates to the technical field of extraction of medicinal active ingredients, in particular to a preparation method of a highly soluble full-component honeysuckle extract. Background technique [0002] Honeysuckle, also known as double flowers and honeysuckle, is the dry flower bud of the Lonicera plant in the family Lonicera. Honeysuckle has attracted much attention because of its effective chemical components and wide medicinal value, and has been widely used in medical, chemical and pharmacological research. It has significant effects in antipyretic, anti-inflammatory, antibacterial, anti-viral, anti-oxidation, anti-ultraviolet, liver and gallbladder protection, and immunity enhancement. Gynecological diseases and other aspects also play a certain role because of their chemical composition and pharmacological effects. Honeysuckle contains volatile oils, organic acids, flavonoids, iridoids, stigmasterol, phenylalanine, carotene, trace...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/355A61K47/69A61K47/36A61K8/9789A61K8/73A23L33/105A23L29/25
CPCA23V2002/00A61K8/73A61K36/355A61K47/36A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2236/55A23L29/25A23L33/105A61K8/9789A61K47/6951A23V2200/30A23V2300/14A23V2250/5112A23V2250/5028A23V2300/10A23V2300/50
Inventor 胡力飞徐浪陈志元袁咏红孙代华
Owner 劲牌持正堂药业有限公司
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